(5-Chloro-2-methoxypyridin-4-yl)boronic acid
- CAS No.
- 475275-69-5
- Chemical Name:
- (5-Chloro-2-methoxypyridin-4-yl)boronic acid
- Synonyms
- oro-2-methoxypyridine-4-boronic acid;2-methoxy-5-chloropyridine-4-boronic acid;5-CHLORO-2-METHOXY-PYRIDINE-4-BORONIC ACID;(5-Chloro-2-Methoxy-4-pyridyl)boronic acid;(5-Chloro-2-methoxypyridin-4-yl)boronicaci;(5-Chloro-2-methoxypyridin-4-yl)boronic acid;5-chlorine-2-methoxy-4-pyridine boronic acid;5-CHLORO-2-METHOXYPYRIDIN-4-YL-4-BORONIC ACID;Boronic acid, B-(5-chloro-2-methoxy-4-pyridinyl)-;Boronic acid, (5-chloro-2-methoxy-4-pyridinyl)- (9CI)
- CBNumber:
- CB4372848
- Molecular Formula:
- C6H7BClNO3
- Molecular Weight:
- 187.39
- MDL Number:
- MFCD06658398
- MOL File:
- 475275-69-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| HS Code | 2933399990 |
(5-Chloro-2-methoxypyridin-4-yl)boronic acid price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 269857 | (5-Chloro-2-methoxypyridin-4-yl)boronic acid Asreported | 475275-69-5 | 500mg | $333 | 2026-06-03 | Buy |
| Usbiological | 269857 | (5-Chloro-2-methoxypyridin-4-yl)boronic acid Asreported | 475275-69-5 | 1g | $556 | 2026-06-03 | Buy |
| Usbiological | 269857 | (5-Chloro-2-methoxypyridin-4-yl)boronic acid Asreported | 475275-69-5 | 2g | $769 | 2026-06-03 | Buy |
| Usbiological | 269857 | (5-Chloro-2-methoxypyridin-4-yl)boronic acid Asreported | 475275-69-5 | 5g | $1067 | 2026-06-03 | Buy |
| Chem-Impex | 18106 | 5-Chloro-2-methoxy-pyridine-4-boronic acid ≥95%(HPLC) | 475275-69-5 | 250MG | $72.31 | 2026-05-19 | Buy |
(5-Chloro-2-methoxypyridin-4-yl)boronic acid Chemical Properties, Uses, Production
Uses
5-Chloro-2-methoxypyridine-4-boronic acid
Synthesis
13473-01-3
121-43-7
475275-69-5
Under nitrogen protection, 300 g of anhydrous tetrahydrofuran was added to the reaction flask with stirring turned on, followed by the addition of 17 g of 2-methoxy-5-chloropyridine and cooling of the reaction system to -30 °C. Slowly 70mL of 2.0M n-butyllithium dichloromethane solution was added dropwise. After the dropwise addition was completed, stirring was continued for 30 minutes, and then 26 g of 1,4,7-trimethyl-1,4,7-triazacyclononane was slowly added dropwise. After the reaction mixture was kept at -30°C for 2 hours, 26 mL of trimethyl borate was added slowly dropwise and stirring was continued for 1 hour. Subsequently, the reaction system was slowly warmed to room temperature and stirred for 1 hour. 400 g of concentrated hydrochloric acid was added to the reaction mixture and stirred for 1 hour for hydrolysis reaction. Stirring was stopped and allowed to stand for layering. The organic layer was separated and the aqueous layer was extracted three times with 100 g of petroleum ether. All organic layers were combined, dried with 50 g of anhydrous sodium sulfate and filtered. The filtrate was concentrated to dryness under reduced pressure to give 16 g of the target product 5-chloro-2-methoxy-4-pyridineboronic acid.
References
[1] Patent: CN102718785, 2016, B. Location in patent: Paragraph 0038; 0039
(5-Chloro-2-methoxypyridin-4-yl)boronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
View Latest Price from (5-Chloro-2-methoxypyridin-4-yl)boronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | (5-CHLORO-2-METHOXYPYRIDIN-4-YL)BORONIC ACID
475275-69-5
|
$1.00 | 1KG | 97%-99% | 1kg;5kg;100kg | Career Henan Chemical Co |
-
- (5-CHLORO-2-METHOXYPYRIDIN-4-YL)BORONIC ACID
475275-69-5
- $1.00
- 97%-99%
- Career Henan Chemical Co
