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4-Aminotetrahydropyran

4-Aminotetrahydropyran Structure
4-Aminotetrahydropyran structure
CAS No.
38041-19-9
Chemical Name:
4-Aminotetrahydropyran
Synonyms
TETRAHYDRO-2H-PYRAN-4-AMINE;oxan-4-amine;TETRAHYDRO-PYRAN-4-YLAMINE;4-Aminotetrahyropyran;4-AMINOTETRAHYDROPYRAN;Tetrahydropyran-4-amine;Noe Marioni, M.D., PLLC;4-Aminotetrahydro-2H-pyran;4-Aminotetrahydropyran?New;2H-PYRAN-4-AMINE, TETRAHYDRO-
CBNumber:
CB4376785
Molecular Formula:
C5H11NO
Molecular Weight:
101.15
MDL Number:
MFCD02179436
MOL File:
38041-19-9.mol
MSDS File:
SDS
Last updated:2026-01-13 11:17:15
Product description Number Pack Size Price
4-Aminotetrahydropyran 97% 711357 1g $167
Tetrahydro-2H-pyran-4-amine min. 95.0 % A2060 5G $65
Tetrahydro-2H-pyran-4-amine min. 95.0 % A2060 25G $213
4-Aminotetrahydropyran A630040 5g $195
4-Aminotetrahydropyran 98% BP-10175 5G $215
More product size
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4-Aminotetrahydropyran Properties

Boiling point 60 °C
Density 0.977 g/cm3 at 25 °C
refractive index n20/D 1.463
Flash point 54°C
storage temp. Keep in dark place,Inert atmosphere,2-8°C
pka 9.63±0.20(Predicted)
form liquid
color Colourless
InChI InChI=1S/C5H11NO/c6-5-1-3-7-4-2-5/h5H,1-4,6H2
InChIKey AHVQYHFYQWKUKB-UHFFFAOYSA-N
SMILES C1OCCC(N)C1
CAS DataBase Reference 38041-19-9(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H226-H302-H318
Precautionary statements  P210-P233-P240-P280-P301+P312-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  10-34-41-22-37/18
Safety Statements  16-26-36/37/39-39
RIDADR  2734
WGK Germany  1
HazardClass  IRRITANT
PackingGroup  Ⅲ
HS Code  29321900
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
Flam. Liq. 3
NFPA 704
1
2 0

4-Aminotetrahydropyran price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 711357 4-Aminotetrahydropyran 97% 38041-19-9 1g $167 2026-03-19 Buy
TCI Chemical A2060 Tetrahydro-2H-pyran-4-amine min. 95.0 % 38041-19-9 5G $65 2026-03-19 Buy
TCI Chemical A2060 Tetrahydro-2H-pyran-4-amine min. 95.0 % 38041-19-9 25G $213 2026-03-19 Buy
TRC A630040 4-Aminotetrahydropyran 38041-19-9 5g $195 2021-12-16 Buy
BroadPharm BP-10175 4-Aminotetrahydropyran 98% 38041-19-9 5G $215 2021-12-16 Buy
Product number Packaging Price Buy
711357 1g $167 Buy
A2060 5G $65 Buy
A2060 25G $213 Buy
A630040 5g $195 Buy
BP-10175 5G $215 Buy

4-Aminotetrahydropyran Chemical Properties,Uses,Production

Description

4-Aminotetrahydropyran contains the tetrahydropyran ring, which is the most frequently reported three-dimensional ring system in marketed drugs, and is second only to the phenyl ring when two-dimensional rings are included. It can be used as reactant/reagent in synthesis of aminothiazole compounds for use in treatment of cancer. Its scaffold is very useful in the drug discovery for cancer treatment.

Application

4-Aminotetrahydropyran can be used as reactant/reagent in synthesis of aminothiazole compounds for use in treatment of cancer.

Synthesis

TETRAHYDRO-PYRAN-4-ONE OXIME

61128-73-2

4-Aminotetrahydropyran

38041-19-9

General procedure for the synthesis of 4-aminotetrahydropyran from dihydro-2H-pyran-4(3H)-one oxime: Raney Ni (10%) was added to a stirred solution of compound 2.2 (1.0 g, 8.7 mmol) in methanol (50 mL) and the resulting mixture was stirred for 5 hr at room temperature in a hydrogen atmosphere. The progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the catalyst was removed by filtration and the methanol solvent in the filtrate was concentrated in vacuum to afford the target product 4-aminotetrahydropyran (Compound 2.3, 0.5 g, 57% yield).

References

[1] Journal of Medicinal Chemistry, 2006, vol. 49, # 7, p. 2210 - 2221
[2] Patent: US2009/82423, 2009, A1. Location in patent: Page/Page column 23
[3] Patent: US5707989, 1998, A
[4] Patent: US5821240, 1998, A
[5] Patent: US5977102, 1999, A

4-Aminotetrahydropyran synthesis

29943-42-8
38041-19-9
Synthesis of 4-Aminotetrahydropyran from Tetrahydro-4H-pyran-4-one

4-Aminotetrahydropyran Preparation Products And Raw materials

Raw materials

Ammonium formate Tetrahydro-4H-pyran-4-one Palladium N-BENZHYDRYL-TETRAHYDRO-2H-PYRAN-4-AMINE di(tetrahydropyran-4-yl)amine
Tetrahydro-pyran-4-yl)-hydrazine TETRAHYDRO-PYRAN-4-ONE OXIME TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE Tetrahydro-4-pyranol Tetrahydro-2H-pyran-4-carboxylic acid

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Preparation Products

4-Aminotetrahydropyran hydrochloride

4-Aminotetrahydropyran Suppliers

Global( 372)Suppliers
Supplier Tel Email Country ProdList Advantage
BTC Nantong Pharmaceuticals Technology Co.,Ltd
+86-0513-81283365 Info@btcpharm.com China 251 58
BTC pharm India
+918790379245 banny.janga@btcpharm.com India 1262 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5235 58
Nanjing Fred Technology Co., Ltd 		+86-25-84696168 +86-15380713688 Austin@fredbio.com China 2428 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29640 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13815 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21592 55
Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
Supplier Advantage
BTC Nantong Pharmaceuticals Technology Co.,Ltd
58
BTC pharm India
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Nanjing Fred Technology Co., Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Nanjing Finetech Chemical Co., Ltd. 		55

View Lastest Price from 4-Aminotetrahydropyran manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Aminotetrahydropyran pictures 2026-04-17 4-Aminotetrahydropyran
38041-19-9
 US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
4-Aminotetrahydropyran pictures 2026-03-20 4-Aminotetrahydropyran
38041-19-9
 US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
4-Aminotetrahydropyran pictures 2025-11-18 4-Aminotetrahydropyran
38041-19-9
 US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited

4-Aminotetrahydropyran Spectrum

4-Aminotetrahydropyran(38041-19-9)1HNMR4-Aminotetrahydropyran(38041-19-9)FT-IR

38041-19-9(4-Aminotetrahydropyran)Related Search:

Tetrahydro-2H-pyran-4-carboxylic acid Tetrahydropyran Centchroman Tetrahydro-4H-pyran-4-one AMINOACETONITRILE HYDROGEN SULFATE
4-AMINOTETRAHYDROPYRAN, HCL,4-AMINOTETRAHYDROPYRAN HYDROCHLORIDE,4-AMINOTETRAHYDROPYRAN HYDROCHLORIDE (TETRAHYDRO-2H-PYRAN-4-AMINE HYDROCHLORIDE) tetrahydropyran-4,4-dicarboxylic acid Tetrahydropyran-4-carbaldehyde Tetrahydropyran-4-boronic acid pinacol ester TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID METHYLAMIDE
TETRAHYDRO-PYRAN-3-YLAMINE HYDROCHLORIDE 4,4,5,5-Tetramethyl-2-(tetrahydro-2H-pyran-3-yl)-1,3,2-dioxaborolane Gentamicin KANAMYCIN MEPARTRICIN
Geneticin Nystatin picromycin

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