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Tetrahydro-2H-pyran-4-carboxamide

Tetrahydro-2H-pyran-4-carboxamide structure

CAS No.: 344329-76-6

Chemical Name:: Tetrahydro-2H-pyran-4-carboxamide

Synonyms: oxane-4-carboxamide;4-CARBAMOYLTETRAHYDROPYRAN;Tetrahydropyran-4-carboxamid;4-tetrahydropyrancarboxamide;1-benzothiophen-7-ylmethanol;tetrahydropyran-4-carboxamide;4-Carbamoyltetrahydro-2H-pyran;4-Carbamoyltetrahydropyran, 98%;Tetrahydro-2H-pyran-4-carboxamide;2H-Pyran-4-carboxamide, tetrahydro-

CBNumber:: CB5311628

Molecular Formula:: C6H11NO2

Molecular Weight:: 129.16

MDL Number:: MFCD08235066

MOL File:: 344329-76-6.mol

MSDS File:: SDS

Last updated:2026-09-12 18:53:29

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Tetrahydro-2H-pyran-4-carboxamide Properties

Melting point	181-183
Boiling point	312.1±31.0 °C(Predicted)
Density	1.114
storage temp.	Sealed in dry,Room Temperature
pka	16.31±0.20(Predicted)
form	solid
color	White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P271-P280
Hazard Codes	Xi,Xn
Risk Statements	22-20/21/22
Safety Statements	24/25-36/37
Hazard Note	Irritant/Keep Cold
HazardClass	IRRITANT
HS Code	29339900

Tetrahydro-2H-pyran-4-carboxamide price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR9367	Tetrahydro-2H-pyran-4-carboxamide 98%	344329-76-6	1g	$52	2026-06-04	Buy
Apolloscientific	OR9367	Tetrahydro-2H-pyran-4-carboxamide 98%	344329-76-6	5g	$117	2026-06-04	Buy
Matrix Scientific	064403	Tetrahydro-2H-pyran-4-carboxamide	344329-76-6	500.00mg	$315	2026-05-18	Buy
Synthonix	T3714	Tetrahydro-2H-pyran-4-carboxamide 98%	344329-76-6	250mg	$63	2026-05-06	Buy
Synthonix	T3714	Tetrahydro-2H-pyran-4-carboxamide 98%	344329-76-6	1g	$68	2026-05-06	Buy

Product number	Packaging	Price	Buy
OR9367	1g	$52	Buy
OR9367	5g	$117	Buy
064403	500.00mg	$315	Buy
T3714	250mg	$63	Buy
T3714	1g	$68	Buy

Tetrahydro-2H-pyran-4-carboxamide Chemical Properties,Uses,Production

Chemical Properties

White solid

Synthesis

110238-91-0

344329-76-6

The general procedure for the synthesis of tetrahydropyran-4-carboxamide from methyl tetrahydropyran-4-carboxylate was as follows: tetrahydro-2H-pyran-4-carboxylic acid methyl ester (7 g, 48.6 mmol) was mixed with 30% ammonia (20 mL) in a closed reaction flask, and the reaction was stirred at room temperature for 18 hours. Upon completion of the reaction, the excess ammonia was removed by distillation under reduced pressure and the residue was recrystallized from ethanol to give 5.6 g (89% yield) of the target product, tetrahydro-2H-pyran-4-carboxamide. The structure of the product was confirmed by 1H NMR (401 MHz, DMSO-d6) with chemical shifts δ ppm of 7.21 (br.s, 1H), 6.73 (br.s, 1H), 3.90-3.80 (m, 2H), 3.30-3.23 (m, 2H), 2.36-2.24 (m, 1H), 1.66-1.47 (m, 4H ).

References

[1] Patent: WO2012/113774, 2012, A1. Location in patent: Page/Page column 41-42
[2] Patent: US2013/324551, 2013, A1. Location in patent: Paragraph 0326; 0327
[3] ChemMedChem, 2015, vol. 10, # 2, p. 276 - 295
[4] Patent: WO2015/62486, 2015, A1. Location in patent: Paragraph 00325
[5] Patent: US2007/111984, 2007, A1. Location in patent: Page/Page column 45

Tetrahydro-2H-pyran-4-carboxamide Preparation Products And Raw materials

Raw materials

Tetrahydro-2H-pyran-4-carbonyl chloride Tetrahydro-2H-pyran-4-carboxylic acid Methyl tetrahydropyran-4-carboxylate Ammonia

Preparation Products

4-Cyanotetrahydro-4H-pyran

Tetrahydro-2H-pyran-4-carboxamide Suppliers

Global( 123)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Ark Pharm, Inc.	847-367-3680	sales@arkpharminc.com	United States	1669	56
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Shanghai Jian Chao Chemical Technology Co., Ltd.	150-2103-5486 18017383231	983544897@qq.com	China	9336	55
9ding chemical ( Shanghai) Limited	4009209199	sales@9dingchem.com	China	18201	56
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	29985	65

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Ark Pharm, Inc.	56
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Capot Chemical Co., Ltd	66
Beijing Ouhe Technology Co., Ltd	60
Pure Chemistry Scientific Inc.	62
Shanghai Jian Chao Chemical Technology Co., Ltd.	55
9ding chemical ( Shanghai) Limited	56
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65

View Lastest Price from Tetrahydro-2H-pyran-4-carboxamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE 344329-76-6	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2024-01-08	tetrahydro-2H-pyran-4-carboxamide 344329-76-6	$25.00	1g	99.96%	500ton	Wuhan Boyuan Import & Export Co., LTD
2019-07-06	4-Carbamoyltetrahydropyran 344329-76-6	$1.00	1KG	98%	500kg	Career Henan Chemical Co

TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE
344329-76-6
$1.10
99.00%
Dideu Industries Group Limited

tetrahydro-2H-pyran-4-carboxamide
344329-76-6
$25.00
99.96%
Wuhan Boyuan Import & Export Co., LTD

4-Carbamoyltetrahydropyran
344329-76-6
$1.00
98%
Career Henan Chemical Co

Tetrahydro-2H-pyran-4-carboxamide Spectrum

TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE(344329-76-6)¹HNMR

344329-76-6(Tetrahydro-2H-pyran-4-carboxamide)Related Search:

TETRAHYDRO-2H-PYRAN-4-YLACETYL CHLORIDE Tetrahydro-4H-pyran-4-one 3,6-dihydro-2H-pyran Methyl tetrahydropyran-4-carboxylate 2-methyloxan-4-one

Tetrahydro-4-pyranol 4-BROMOMETHYLTETRAHYDROPYRAN 4-BROMO-TETRAHYDROPYRAN Tetrahydropyran-4-carbaldehyde 4-Amidinotetrahydro-2H-pyran hydrochloride

Tetrahydropyran-4-boronic acid pinacol ester Tetrahydropyranyl-4-acetic acid Tetrahydro-2H-pyran-4-carboxylic acid 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL Tetrahydro-pyran-4-yl)-hydrazine

Ethyl Tetrahydropyran-4-Carboxylate 4-(Dimethylamino)tetrahydro-2H-pyran Tetrahydro-pyran-3-carbaldehyde

1of4

Tetrahydro-2H-pyran-4-carboxamide ,98% tetrahydropyran-4-carboxamide 3,4,5,6-Tetrahydro-2H-pyran-4-carboxamide 4-CARBAMOYLTETRAHYDROPYRAN Tetrahydropyran-4-carboxamid Tetrahydro-2H-pyran-4-carboxamide 98% 4-Carbamoyltetrahydro-2H-pyran 2H-Pyran-4-carboxamide, tetrahydro- 4-tetrahydropyrancarboxamide oxane-4-carboxamide tetrahydro-pyran-4-carboxylic acid amide 1-benzothiophen-7-ylmethanol TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE ISO 9001：2015 REACH 4-Carbamoyltetrahydropyran, 98% Tetrahydro-2H-pyran-4-carboxamide - [T3714] Tetrahydro-2H-pyran-4-carboxamide 344329-76-6 blocks Carboxes Heterocycles