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2-(Trifluoromethyl)phenothiazine

2-(Trifluoromethyl)phenothiazine structure

CAS No.: 92-30-8

Chemical Name:: 2-(Trifluoromethyl)phenothiazine

Synonyms: 2 - Trifluoro Phenothiazine;TIMTEC-BB SBB003058;Trifluoromethylphenothiazine;2-Trifluomethylphenothiazine;2-TRIFLUORO-10H-PHENOTHIAZINE;2-Triflouromethylphenothiazine;2-(TRIFLOUOMETHYL) PHENOTHIAZINE;2-Trilfluoromethyl Phenothiazine;2-(trifluoromethyl)-phenothiazin;2-(TRIFLUOROMETHYL)PHENOTHIAZINE

CBNumber:: CB4383095

Molecular Formula:: C13H8F3NS

Molecular Weight:: 267.27

MDL Number:: MFCD00005018

MOL File:: 92-30-8.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:54

Product description	Number	Pack Size	Price
2-(Trifluoromethyl)phenothiazine >98.0%(GC)	T1407	25g	$132
2-(Trifluoromethyl)phenothiazine	T791370	5g	$135
2-(Trifluoromethyl)phenothiazine	T791370	25g	$185
2-(Trifluoromethyl)-10H-phenothiazine 97%	PC7694	25g	$80
2-(Trifluoromethyl)phenothiazine	J53736	100g	$100
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2-(Trifluoromethyl)phenothiazine Properties

Melting point	188-190 °C(lit.)
Boiling point	361.1±42.0 °C(Predicted)
Density	1.3491 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	-2.60±0.20(Predicted)
form	Solid
color	Pale Yellow to Light Green
BRN	226580
InChI	InChI=1S/C13H8F3NS/c14-13(15,16)8-5-6-12-10(7-8)17-9-3-1-2-4-11(9)18-12/h1-7,17H
InChIKey	RKGYJVASTMCSHZ-UHFFFAOYSA-N
SMILES	C1=C2C(SC3=C(N2)C=CC=C3)=CC=C1C(F)(F)F
CAS DataBase Reference	92-30-8(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	877S053KX3
NIST Chemistry Reference	10H-phenothiazine, 2-(trifluoromethyl)-(92-30-8)
EPA Substance Registry System	10H-Phenothiazine, 2-(trifluoromethyl)- (92-30-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P301+P312a-P330-P501a-P264-P270-P301+P312+P330-P501

Hazard Codes

Xn,Xi

Risk Statements

20/21/22-22

Safety Statements

36-37/39-26

WGK Germany

RTECS

SP5620000

Hazard Note

Irritant

TSCA

TSCA listed

HS Code

29349990

NFPA 704

	1
2		0

2-(Trifluoromethyl)phenothiazine price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	T1407	2-(Trifluoromethyl)phenothiazine >98.0%(GC)	92-30-8	25g	$132	2025-07-31	Buy
TRC	T791370	2-(Trifluoromethyl)phenothiazine	92-30-8	5g	$135	2021-12-16	Buy
TRC	T791370	2-(Trifluoromethyl)phenothiazine	92-30-8	25g	$185	2021-12-16	Buy
Apolloscientific	PC7694	2-(Trifluoromethyl)-10H-phenothiazine 97%	92-30-8	25g	$80	2021-12-16	Buy
AK Scientific	J53736	2-(Trifluoromethyl)phenothiazine	92-30-8	100g	$100	2021-12-16	Buy

Product number	Packaging	Price	Buy
T1407	25g	$132	Buy
T791370	5g	$135	Buy
T791370	25g	$185	Buy
PC7694	25g	$80	Buy
J53736	100g	$100	Buy

2-(Trifluoromethyl)phenothiazine Chemical Properties,Uses,Production

Chemical Properties

YELLOW TO GREEN POWDER

Uses

2-(Trifluoromethyl)phenothiazine is used in the synthesis of antitubercolosis pharmaceuticals as well as antiproliferatives.

Definition

ChEBI: 2-(trifluoromethyl)-10H-phenothiazine is a member of phenothiazines.

Synthesis

672-57-1

Ethanethioic acid,S-[2-(acetylamino)phenyl] ester

1204-55-3

92-30-8

GENERAL STEPS: To an oven-dried 25 mL milled-neck test tube fitted with a stirrer, S-(2-acetamidophenyl) thioacetate (0.5 mmol), 3-iodo-4-chlorobenzotrifluoride (0.6 mmol), Cs2CO3 (2.0 mmol), and DMF (3 mL) were added sequentially. The test tube was sealed with a rubber septum, evacuated and replaced with argon for three cycles. The reaction mixture was stirred at 130 °C for 10 hours. Upon completion of the reaction, it was cooled to room temperature, the reaction was quenched with deionized water (20 mL) and extracted with ethyl acetate (20 mL x 3). The organic phases were combined, dried with anhydrous MgSO4 and concentrated under reduced pressure to remove the solvent. The resulting crude product was purified by silica gel column chromatography using gradient elution (eluent: petroleum ether/ethyl acetate) to afford the target compound 2-trifluoromethyl phenothiazine.

References

[1] Synthetic Communications, 2017, vol. 47, # 7, p. 710 - 715

2-(Trifluoromethyl)phenothiazine Preparation Products And Raw materials

Raw materials

Antimicrobial Flufenamic acid Sulphur 3-Methyldiphenylamine 4-CHLORO-3-IODOBENZOTRIFLUORIDE

Ethanethioic acid,S-[2-(acetylamino)phenyl] ester N,N-Dimethylformamide Cesium carbonate

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Preparation Products

Trifluoperazine 3-(2-Trifluoromethyl-10H-phenothiazin-10-yl)propiononitrile Ftormetazine Duoperone

2-(Trifluoromethyl)phenothiazine Suppliers

Global( 246)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-17392712697	1022@dideu.com	China	3995	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52722	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Shenzhen Nexconn Pharmatechs Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
sgtlifesciences pvt ltd	58

View Lastest Price from 2-(Trifluoromethyl)phenothiazine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-12-24	2-(Trifluoromethyl)phenothiazine 92-30-8	US $0.00-0.00 / KG	1KG	99.0%	1000KG	Shaanxi Dideu Medichem Co. Ltd
	2020-01-09	2-(Triflouomethyl) phenothiazine 92-30-8	US $1.00 / KG	1KG	Min98% HPLC	g/kg/ton	Career Henan Chemical Co

2-(Trifluoromethyl)phenothiazine
92-30-8
US $0.00-0.00 / KG
99.0%
Shaanxi Dideu Medichem Co. Ltd

2-(Triflouomethyl) phenothiazine
92-30-8
US $1.00 / KG
Min98% HPLC
Career Henan Chemical Co

2-(Trifluoromethyl)phenothiazine Spectrum

2-(Trifluoromethyl)phenothiazine(92-30-8)MS 2-(Trifluoromethyl)phenothiazine(92-30-8)¹HNMR 2-(Trifluoromethyl)phenothiazine(92-30-8)¹³CNMR 2-(Trifluoromethyl)phenothiazine(92-30-8)IR1 2-(Trifluoromethyl)phenothiazine(92-30-8)IR2

92-30-8(2-(Trifluoromethyl)phenothiazine)Related Search:

(Trifluoromethyl)trimethylsilane Phenothiazine 3-Trifluoromethylphenol Trifluoromethanesulfonic acid Trifluoromethanesulfonic anhydride

4-Bromobenzotrifluoride 4-(Trifluoromethyl)benzaldehyde 3-（trifluoromethyl) Cinnamaldehyde 3-(Trifluoromethyl)benzaldehyde FLUPHENAZINE HYDROCHLORIDE

10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)phenothiazine Oxaflumazine 10-(3-(2-Hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine Fluphenazine decanoate Ciclofenazine

Flutiazin 10-[3-(4-METHYL-1-PIPERAZINYL)PROPYL]-2-TRIFLUOROMETHYL-PHENOTHIAZINE DIHYDROCHLORIDE triflupromazine

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2-(Trifluoromethyl)dibenzothiazine 2-(trifluoromethyl)-phenothiazin 2-(Trifluoromethyl)thiodiphenylamine Phenothiazine, 2-(trifluoromethyl)- Trifluoromethylphenothiazine TIMTEC-BB SBB003058 2-Trilfluoromethyl Phenothiazine 2-(TRIFLOUOMETHYL) PHENOTHIAZINE 2-TRIFLUORO-10H-PHENOTHIAZINE 2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE 2-Triflouromethylphenothiazine 10H-Phenothiazine, 2-(trifluoromethyl)- 2-(Trifluoromethyl)phenothiazine97% 2 - Trifluoro Phenothiazine 2-(TRIFLUOROMETHYL)PHENOTHIAZINEFLUPHEANZINE 2-TrifluoroMethyl-10H-phenothiazine, 98%+ 2-(TRIFLUOROMETHYL)PHENOTHIAZINE 2-(trifluoromethyl)-10h-phenothiazin 2-(Trifluoromethyl)-10H-dibenzo[b,e][1,4]thiazine (2R,5R)-2,5-bis(2,4,5-trimethoxyphenyl)oxolane 2-Trifluomethylphenothiazine 92-30-8 C13H8F3SN C13H8F3NS Trifluoperazine Fluphenazine Trifluoperzine Xanthones