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2-(Trifluoromethyl)phenothiazine

2-(Trifluoromethyl)phenothiazine structure

CAS No.: 92-30-8

Chemical Name:: 2-(Trifluoromethyl)phenothiazine

Synonyms: 2 - Trifluoro Phenothiazine;Compound PDK0397;TIMTEC-BB SBB003058;Trifluoromethylphenothiazine;2-Trifluomethylphenothiazine;2-TRIFLUORO-10H-PHENOTHIAZINE;2-Triflouromethylphenothiazine;2-(TRIFLOUOMETHYL) PHENOTHIAZINE;2-Trilfluoromethyl Phenothiazine;2-(trifluoromethyl)-phenothiazin

CBNumber:: CB4383095

Molecular Formula:: C13H8F3NS

Molecular Weight:: 267.27

MDL Number:: MFCD00005018

MOL File:: 92-30-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 01:59:49

Product description	Number	Pack Size	Price
2-(Trifluoromethyl)phenothiazine >98.0%(GC)	T1407	25g	$134
2-(Trifluoromethyl)phenothiazine Asreported	291312	2g	$333
2-(Trifluoromethyl)phenothiazine Asreported	291312	5g	$459
2-(Trifluoromethyl)phenothiazine Asreported	291312	10g	$613
2-(Trifluoromethyl)phenothiazine Asreported	291312	25g	$902
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2-(Trifluoromethyl)phenothiazine Properties

Melting point	188-190 °C(lit.)
Boiling point	361.1±42.0 °C(Predicted)
Density	1.3491 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	-2.60±0.20(Predicted)
form	Solid
color	Pale Yellow to Light Green
BRN	226580
InChI	InChI=1S/C13H8F3NS/c14-13(15,16)8-5-6-12-10(7-8)17-9-3-1-2-4-11(9)18-12/h1-7,17H
InChIKey	RKGYJVASTMCSHZ-UHFFFAOYSA-N
SMILES	C1=C2C(SC3=C(N2)C=CC=C3)=CC=C1C(F)(F)F
CAS DataBase Reference	92-30-8(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	877S053KX3
NIST Chemistry Reference	10H-phenothiazine, 2-(trifluoromethyl)-(92-30-8)
EPA Substance Registry System	10H-Phenothiazine, 2-(trifluoromethyl)- (92-30-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P301+P312a-P330-P501a-P264-P270-P301+P312+P330-P501

Hazard Codes

Xn,Xi

Risk Statements

20/21/22-22

Safety Statements

36-37/39-26

WGK Germany

RTECS

SP5620000

Hazard Note

Irritant

TSCA

TSCA listed

HS Code

29349990

REACH Registrations

Active

NFPA 704

	1
2		0

2-(Trifluoromethyl)phenothiazine price More Price(56)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	T1407	2-(Trifluoromethyl)phenothiazine >98.0%(GC)	92-30-8	25g	$134	2026-04-30	Buy
Usbiological	291312	2-(Trifluoromethyl)phenothiazine Asreported	92-30-8	2g	$333	2026-06-03	Buy
Usbiological	291312	2-(Trifluoromethyl)phenothiazine Asreported	92-30-8	5g	$459	2026-06-03	Buy
Usbiological	291312	2-(Trifluoromethyl)phenothiazine Asreported	92-30-8	10g	$613	2026-06-03	Buy
Usbiological	291312	2-(Trifluoromethyl)phenothiazine Asreported	92-30-8	25g	$902	2026-06-03	Buy

Product number	Packaging	Price	Buy
T1407	25g	$134	Buy
291312	2g	$333	Buy
291312	5g	$459	Buy
291312	10g	$613	Buy
291312	25g	$902	Buy

2-(Trifluoromethyl)phenothiazine Chemical Properties,Uses,Production

Chemical Properties

YELLOW TO GREEN POWDER

Uses

2-(Trifluoromethyl)phenothiazine is used in the synthesis of antitubercolosis pharmaceuticals as well as antiproliferatives.

Definition

ChEBI: 2-(trifluoromethyl)-10H-phenothiazine is a member of phenothiazines.

Synthesis

672-57-1

Ethanethioic acid,S-[2-(acetylamino)phenyl] ester

1204-55-3

92-30-8

GENERAL STEPS: To an oven-dried 25 mL milled-neck test tube fitted with a stirrer, S-(2-acetamidophenyl) thioacetate (0.5 mmol), 3-iodo-4-chlorobenzotrifluoride (0.6 mmol), Cs2CO3 (2.0 mmol), and DMF (3 mL) were added sequentially. The test tube was sealed with a rubber septum, evacuated and replaced with argon for three cycles. The reaction mixture was stirred at 130 °C for 10 hours. Upon completion of the reaction, it was cooled to room temperature, the reaction was quenched with deionized water (20 mL) and extracted with ethyl acetate (20 mL x 3). The organic phases were combined, dried with anhydrous MgSO4 and concentrated under reduced pressure to remove the solvent. The resulting crude product was purified by silica gel column chromatography using gradient elution (eluent: petroleum ether/ethyl acetate) to afford the target compound 2-trifluoromethyl phenothiazine.

References

[1] Synthetic Communications, 2017, vol. 47, # 7, p. 710 - 715

2-(Trifluoromethyl)phenothiazine Preparation Products And Raw materials

Raw materials

Antimicrobial Flufenamic acid Sulphur 3-Methyldiphenylamine 4-CHLORO-3-IODOBENZOTRIFLUORIDE

Ethanethioic acid,S-[2-(acetylamino)phenyl] ester N,N-Dimethylformamide Cesium carbonate

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Preparation Products

Trifluoperazine 3-(2-Trifluoromethyl-10H-phenothiazin-10-yl)propiononitrile Ftormetazine Duoperone

2-(Trifluoromethyl)phenothiazine Suppliers

Global( 258)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-17392712779	1097@dideu.com	China	3989	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10399	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +8619957148339	market18@leapchem.com	China	24569	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501	product@acmec-e.com	China	33301	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Capot Chemical Co.,Ltd.	60
Shenzhen Nexconn Pharmatechs Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
HANGZHOU LEAP CHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58

View Lastest Price from 2-(Trifluoromethyl)phenothiazine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-12-24	2-(Trifluoromethyl)phenothiazine 92-30-8		1KG	99.0%	1000KG	Shaanxi Dideu Medichem Co. Ltd
	2020-01-09	2-(Triflouomethyl) phenothiazine 92-30-8	$1.00	1KG	Min98% HPLC		Career Henan Chemical Co

2-(Trifluoromethyl)phenothiazine
92-30-8
99.0%
Shaanxi Dideu Medichem Co. Ltd

2-(Triflouomethyl) phenothiazine
92-30-8
$1.00
Min98% HPLC
Career Henan Chemical Co

2-(Trifluoromethyl)phenothiazine Spectrum

2-(Trifluoromethyl)phenothiazine(92-30-8)MS 2-(Trifluoromethyl)phenothiazine(92-30-8)¹HNMR 2-(Trifluoromethyl)phenothiazine(92-30-8)¹³CNMR 2-(Trifluoromethyl)phenothiazine(92-30-8)IR1 2-(Trifluoromethyl)phenothiazine(92-30-8)IR2

92-30-8(2-(Trifluoromethyl)phenothiazine)Related Search:

(Trifluoromethyl)trimethylsilane Phenothiazine 3-Trifluoromethylphenol Trifluoromethanesulfonic acid Trifluoromethanesulfonic anhydride

4-Bromobenzotrifluoride 4-(Trifluoromethyl)benzaldehyde 3-（trifluoromethyl) Cinnamaldehyde 3-(Trifluoromethyl)benzaldehyde FLUPHENAZINE HYDROCHLORIDE

Flutiazin Ciclofenazine Oxaflumazine Fluphenazine decanoate 10-[3-(4-METHYL-1-PIPERAZINYL)PROPYL]-2-TRIFLUOROMETHYL-PHENOTHIAZINE DIHYDROCHLORIDE

FLUPHENAZINE Trifluoperazine triflupromazine

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2-(Trifluoromethyl)dibenzothiazine 2-(trifluoromethyl)-phenothiazin 2-(Trifluoromethyl)thiodiphenylamine Phenothiazine, 2-(trifluoromethyl)- Trifluoromethylphenothiazine TIMTEC-BB SBB003058 2-Trilfluoromethyl Phenothiazine 2-(TRIFLOUOMETHYL) PHENOTHIAZINE 2-TRIFLUORO-10H-PHENOTHIAZINE 2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE 2-Triflouromethylphenothiazine 10H-Phenothiazine, 2-(trifluoromethyl)- 2-(Trifluoromethyl)phenothiazine97% 2 - Trifluoro Phenothiazine 2-(TRIFLUOROMETHYL)PHENOTHIAZINEFLUPHEANZINE 2-TrifluoroMethyl-10H-phenothiazine, 98%+ 2-(TRIFLUOROMETHYL)PHENOTHIAZINE 2-(trifluoromethyl)-10h-phenothiazin 2-(Trifluoromethyl)-10H-dibenzo[b,e][1,4]thiazine (2R,5R)-2,5-bis(2,4,5-trimethoxyphenyl)oxolane 2-Trifluomethylphenothiazine Compound PDK0397 92-30-8 C13H8F3SN C13H8F3NS Trifluoperazine Fluphenazine Trifluoperzine Xanthones