RUSCOGENIN
- CAS No.
- 472-11-7
- Chemical Name:
- RUSCOGENIN
- Synonyms
- RUSCOGENINE;HeModren;FlebopoM;Ruscogeni;RUSCOGENIN;Rectolander;Ruscorectal;RUSCOGENIN(P);Ruscogenins CRS;RUSCOGENIN USP/EP/BP
- CBNumber:
- CB4411307
- Molecular Formula:
- C27H42O4
- Molecular Weight:
- 430.63
- MDL Number:
- MFCD00210550
- MOL File:
- 472-11-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 198-202℃ |
|---|---|
| Boiling point | 563.1±50.0 °C(Predicted) |
| Density | 1.18 |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| pka | 14.56±0.70(Predicted) |
| form | Solid |
| color | White |
| Major Application |
metabolomics vitamins, nutraceuticals, and natural products |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChIKey | QMQIQBOGXYYATH-ORLFXEBYNA-N |
| SMILES | C[C@H](CC1)CO[C@]21O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC=C6C[C@@H](O)C[C@@H](O)[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@@]3([H])[C@@H]2C |
| EWG's Food Scores | 1 |
| FDA UNII | BXI92R2VUJ |
| UNSPSC Code | 41116107 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HS Code | 29389090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
RUSCOGENIN price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB00295 | Ruscogenin ≥98% (HPLC) | 472-11-7 | 5 mg | $352 | 2026-04-30 | Buy |
| Cayman Chemical | 25217 | Ruscogenin ≥95% | 472-11-7 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 25217 | Ruscogenin ≥95% | 472-11-7 | 5mg | $153 | 2026-04-30 | Buy |
| Cayman Chemical | 25217 | Ruscogenin ≥95% | 472-11-7 | 10mg | $268 | 2026-04-30 | Buy |
| Cayman Chemical | 25217 | Ruscogenin ≥95% | 472-11-7 | 25mg | $587 | 2026-04-30 | Buy |
RUSCOGENIN Chemical Properties, Uses, Production
Chemical Properties
White powder
Uses
A major steroidal sapogenin from Radix ophiopogon japonicus with robust anti-inflammatory and anti-thrombotic activities. Studies suggest that it inhibits adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-α (TNF-α) in a concentration-dependent manner.
Definition
ChEBI: Ruscogenin is a triterpenoid.
Biological Activity
Ruscogenin is a well-known compound for down-regulating nuclear factor kappa B (NF-KB), intercellular adhesion molecule-1 (ICAM-1), tissue factor (TF), inducible NO synthase (iNOS), and modulating inflammatory pathways. It displays anti-inflammatory properties by inhibiting lipopolysaccharide (LPS)-induced acute lung injury (ALI), and improving diabetic nephropathy in in vivo studies. Ruscogenin also exerts neuroprotective properties and protects the brain against ischemic injury in mouse model. It elicits anti-tumor properties by inducing ferroptosis in pancreatic cancer cells in both in vitro and in vivo studies.
target
PGE | TNF-α | NF-kB | p65 | NO | NOS | COX | ERK | JNK | Akt | p38MAPK | PKA | cAMP | IL Receptor
RUSCOGENIN Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Moqi Biological Technology Co., LTD | 13341702378 | 190129269@qq.com | China | 9998 | 58 |
| Chengdu Biopurify Ltd. | 82633860 18982077548 | cwb1@biopurify.cn | China | 4630 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Shenzhen Sungening Bio-Tech Co., Ltd | +86-0755-89668383 | sales@sungening.com | China | 1319 | 65 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
View Latest Price from RUSCOGENIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-14 | Ruscogenin
472-11-7
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-08-07 | RUSCOGENIN
472-11-7
|
$1.00-45.00 | 1KG | 99% | 2000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2023-02-24 | Ruscogenin
472-11-7
|
5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Ruscogenin
472-11-7
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- RUSCOGENIN
472-11-7
- $1.00-45.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Ruscogenin
472-11-7
- $0.00
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
