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3,5-Lutidine

3,5-Lutidine Structure
3,5-Lutidine structure
CAS No.
591-22-0
Chemical Name:
3,5-Lutidine
Synonyms
35L;Lutidine,98%;3,5-LUTIDINE;3,5-Lutidine>3,5-Lutidine,99%;3,5-LUTIDINE, 98+%;3,5-Dimetylpyridine;Nicotine Impurity 6;3,5-dimethyl-pyridin;3,5-DIMETHYLPYRIDINE
CBNumber:
CB4412061
Molecular Formula:
C7H9N
Molecular Weight:
107.15
MDL Number:
MFCD00006404
MOL File:
591-22-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-10 10:27:16
Product description Number Pack Size Price
3,5-Lutidine ≥98% L4206 100ml $74.2
3,5-Lutidine >98.0%(GC) L0068 25mL $18
3,5-Lutidine >98.0%(GC) L0068 500mL $166
3,5-Lutidine ≥98% L4206 500ml $150
3,5-Lutidine 99+% 232344 25ml $156
More product size
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3,5-Lutidine Properties

Melting point -9 °C (lit.)
Boiling point 169-170 °C (lit.)
Density 0.939 g/mL at 25 °C (lit.)
vapor pressure 1.5 mm Hg ( 20 °C)
refractive index n20/D 1.504(lit.)
FLAVIS Number 14.106 | 3,5-Dimethylpyridine
Flash point 128 °F
storage temp. 2-8°C
pka 6.15(at 25℃)
form Liquid
color Clear yellow
Water Solubility 33 g/L (20 ºC)
Sensitive Hygroscopic
BRN 105682
Henry's Law Constant 1.4×100 mol/(m3Pa) at 25℃, Andon et al. (1954)
InChI 1S/C7H9N/c1-6-3-7(2)5-8-4-6/h3-5H,1-2H3
InChIKey HWWYDZCSSYKIAD-UHFFFAOYSA-N
SMILES Cc1cncc(C)c1
LogP 1.780
Indirect Additives used in Food Contact Substances 3,5-DIMETHYLPYRIDINE
CAS DataBase Reference 591-22-0(CAS DataBase Reference)
FDA UNII 6Q4YPZ045V
NIST Chemistry Reference Pyridine, 3,5-dimethyl-(591-22-0)
EPA Substance Registry System 3,5-Dimethylpyridine (591-22-0)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS06
Signal word  Danger
Hazard statements  H226-H302-H311+H331-H314
Precautionary statements  P210-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn,F,Xi,T
Risk Statements  10-20/21/22-36/37/38-41-34-23/25-21
Safety Statements  16-26-36-36/37-45-36/37/39
RIDADR  UN 1993 3/PG 3
WGK Germany  3
F  8
Hazard Note  Irritant/Flammable
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29333999
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Eye Dam. 1
Flam. Liq. 3
Skin Corr. 1B
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
2
3 1

3,5-Lutidine price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L4206 3,5-Lutidine ≥98% 591-22-0 100ml $74.2 2026-04-30 Buy
TCI Chemical L0068 3,5-Lutidine >98.0%(GC) 591-22-0 25mL $18 2026-04-30 Buy
TCI Chemical L0068 3,5-Lutidine >98.0%(GC) 591-22-0 500mL $166 2026-04-30 Buy
Sigma-Aldrich L4206 3,5-Lutidine ≥98% 591-22-0 500ml $150 2026-04-30 Buy
Usbiological 232344 3,5-Lutidine 99+% 591-22-0 25ml $156 2021-12-16 Buy
Product number Packaging Price Buy
L4206 100ml $74.2 Buy
L0068 25mL $18 Buy
L0068 500mL $166 Buy
L4206 500ml $150 Buy
232344 25ml $156 Buy

3,5-Lutidine Chemical Properties,Uses,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

3,5-Lutidine is a reactant used in the synthesis of phthalazine and pyrazine compounds, as well as other pharmaceuticals.

Synthesis Reference(s)

Synthesis, p. 573, 1994 DOI: 10.1055/s-1994-25526

Flammability and Explosibility

Flammable

Purification Methods

Dry 3,5-lutidine with sodium and fractionally distil it through a Todd column (p 11) packed with glass helices. Dissolve (100mL) in dilute HCl (1:4) and steam distil this until 1L of distillate is collected. Excess conc NaOH is added to the residue which is again steam distilled. The base is extracted from the distillate, using diethyl ether. The extract is dried over K2CO3, and distilled. It is then fractionally crystallised by partial freezing. The hydrochloride has m 229o(sublimes at 190-231o), and the picrate has m 242-243o(dec, from H2O), 249-250o(dec, from AcOH). [Beilstein 20 II 161, 20 III/IV 2788, 20/6 V 60.]

Toxics Screening Level

The initial threshold screening level (ITSL) for 3,5-lutidine is 0.1 μg/m3 (annual averaging time).

3,5-Lutidine Preparation Products And Raw materials

Raw materials

Methyl vinyl sulfone

Preparation Products

3,5-DIMETHYLPYRIDIN-4-AMINE 5-Methylpyridin-3-amine 3,5-bis(chloromethyl)pyridine ETHYL METHYLPHOSPHONIC ACID 3-CYANO-5-METHYLPYRIDINE
METHYL 5-METHYLNICOTINATE 2,3,5-Collidine 1,3,5-Trimethyl-1,2-dihydropyridin-2-one 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-(1,1-diMethylethyl)-5-Methyl- 3,5-Dimethylpiperidine
3,5-dimethylpyridine-4-carboxylic acid

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3,5-Lutidine Suppliers

Global( 364)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
Jiangsu Zhongbang Pharmaceutical Co., Ltd. 		025-87151996 zbsales@chinaredsun.com CHINA 32 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29819 58
Shandong chuangyingchemical Co., Ltd. 		18853181302 sale@chuangyingchem.com CHINA 5906 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Richest Group Ltd 		18017061086 oled@richest-group.com CHINA 5600 58
Antai Fine Chemical Technology Co.,Limited 		18503026267 info@antaichem.com CHINA 9636 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8828 58
Jinan Qinmu Fine Chemical Co.,Ltd. 		+8618660799346 sales@qinmuchem.com China 1008 58
Supplier Advantage
Henan Tianfu Chemical Co.,Ltd. 		55
Jiangsu Zhongbang Pharmaceutical Co., Ltd. 		55
career henan chemical co 		58
Shandong chuangyingchemical Co., Ltd. 		58
Standardpharm Co. Ltd. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Richest Group Ltd 		58
Antai Fine Chemical Technology Co.,Limited 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
Jinan Qinmu Fine Chemical Co.,Ltd. 		58

View Lastest Price from 3,5-Lutidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-Lutidine pictures 2026-04-30 3,5-Lutidine
591-22-0
 US $0.00 / KG 1KG 99.0% 1000kg/month WUHAN FORTUNA CHEMICAL CO., LTD
3,5-Lutidine pictures 2025-11-18 3,5-Lutidine
591-22-0
 US $1.10 / g 1g 99.00% 100 Tons min Dideu Industries Group Limited
3,5-Lutidine pictures 2020-11-16 3,5-Lutidine
591-22-0
 US $5.00 / Kg/Bag 10Kg/Bag 99% 20 Tons Longyan Tianhua Biological Technology Co., Ltd
  • 3,5-Lutidine pictures
  • 3,5-Lutidine
    591-22-0
  • US $0.00 / KG
  • 99.0%
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • 3,5-Lutidine pictures
  • 3,5-Lutidine
    591-22-0
  • US $1.10 / g
  • 99.00%
  • Dideu Industries Group Limited
  • 3,5-Lutidine pictures
  • 3,5-Lutidine
    591-22-0
  • US $5.00 / Kg/Bag
  • 99%
  • Longyan Tianhua Biological Technology Co., Ltd

3,5-Lutidine Spectrum

3,5-Lutidine(591-22-0)MS3,5-Lutidine(591-22-0)13CNMR3,5-Lutidine(591-22-0)IR13,5-Lutidine(591-22-0)IR23,5-Lutidine(591-22-0)Raman3,5-Lutidine(591-22-0)ESR

591-22-0(3,5-Lutidine )Related Search:

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DIETHYL 2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE 5-ETHYLPYRIDINE-2,3-DICARBOXYLIC ACID PYRIDINITRIL Dimethylpyridine, 2,4-: (2,4-Lutidine),2,4-DIMETHYLPYRIDINE(2,4-LUTIDINE),2,4-LUTIDINE 98+% 3,5-DIETHYL-2-N-PROPYLPYRIDINE
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pyridine,3,5-dimethyl- Lutidine,98% 3 5-LUTIDINE STANDARD FOR GC 3,5-LUTIDINE, 98+% 3,5-DIMETHYLPYRIDINE 98+% 3,5-Dimetylpyridine 3,5-Lutidine,99% 3,5-dimethyl-pyridin 3,5-Lutidine, 98+% 100ML 3,5-LUTIDINE 3,5-DIMETHYLPYRIDINE 3,5-diMethyl pyridine cation 3,5-DIMETHYLPYRIDINE FOR SYNTHESIS 3,5-two Methyl pyridine 35L 3,5-LUTIDINE 3,5-DIMETHYLPYRIDINE Loratadine Impurity 27 3,5-Lutidine> Nicotine Related Compound 2 3,5-Lutidine ISO 9001：2015 REACH 3,5-dimethhylpyridine 3,5-LUTIDINE For Synthesis Nicotine Impurity 6 3, 5-Lutidine 98% For Synthesis 591-22-0 Reagents for Oligosaccharide Synthesis Building Blocks Analytical Standards Alphabetic Analytical Chromatography Product Catalog C7 and C8 Pyridines Heterocyclic Building Blocks Biochemistry Reagents for Oligosaccharide Synthesis Pyridines derivates Heterocyclic Compounds K00001