Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>3,5-Lutidine

3,5-Lutidine

3,5-Lutidine Structure
3,5-Lutidine structure
CAS No.
591-22-0
Chemical Name:
3,5-Lutidine
Synonyms
3,5-DIMETHYLPYRIDINE;35L;Lutidine,98%;3,5-LUTIDINE;3,5-Lutidine>3,5-Lutidine,99%;3,5-LUTIDINE, 98+%;3,5-Dimetylpyridine;Nicotine Impurity 6;3,5-dimethyl-pyridin
CBNumber:
CB4412061
Molecular Formula:
C7H9N
Molecular Weight:
107.15
MDL Number:
MFCD00006404
MOL File:
591-22-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-24 18:39:39
Request For Quotation

3,5-Lutidine Properties

Melting point -9 °C (lit.)
Boiling point 169-170 °C (lit.)
Density 0.939 g/mL at 25 °C (lit.)
vapor pressure 1.5 mm Hg ( 20 °C)
refractive index n20/D 1.504(lit.)
FLAVIS Number 14.106 | 3,5-Dimethylpyridine
Flash point 128 °F
storage temp. 2-8°C
form Liquid
pka 6.15(at 25℃)
color Clear yellow
Water Solubility 33 g/L (20 ºC)
Specific Heat Capacity Cp(liquid): 1.72 J/(g·K), at 25℃
Sensitive Hygroscopic
BRN 105682
Henry's Law Constant 1.4×100 mol/(m3Pa) at 25℃, Andon et al. (1954)
InChI 1S/C7H9N/c1-6-3-7(2)5-8-4-6/h3-5H,1-2H3
InChIKey HWWYDZCSSYKIAD-UHFFFAOYSA-N
SMILES Cc1cncc(C)c1
LogP 1.780
CAS DataBase Reference 591-22-0(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances 3,5-DIMETHYLPYRIDINE
FDA 21 CFR 177.1520
FDA UNII 6Q4YPZ045V
NIST Chemistry Reference Pyridine, 3,5-dimethyl-(591-22-0)
EPA Substance Registry System 3,5-Dimethylpyridine (591-22-0)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H302-H313-H315-H319-H226
Precautionary statements  P501-P270-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P312-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P301+P312+P330-P403+P235
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn,F,Xi,T
Risk Statements  10-20/21/22-36/37/38-41-34-23/25-21
Safety Statements  16-26-36-36/37-45-36/37/39
RIDADR  UN 1993 3/PG 3
WGK Germany  3
F  8
Hazard Note  Irritant/Flammable
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29333999
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Eye Dam. 1
Flam. Liq. 3
Skin Corr. 1B
REACH Registrations Active
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
2
3 1

3,5-Lutidine price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L4206 3,5-Lutidine ≥98% 591-22-0 100ml $74.2 2026-04-30 Buy
TCI Chemical L0068 3,5-Lutidine >98.0%(GC) 591-22-0 25mL $18 2026-04-30 Buy
TCI Chemical L0068 3,5-Lutidine >98.0%(GC) 591-22-0 500mL $166 2026-04-30 Buy
TRC TRC-L478040-5G 3,5-Lutidine 591-22-0 5g $84 2026-06-03 Buy
TRC TRC-L478040-50G 3,5-Lutidine 591-22-0 50g $145 2026-06-03 Buy
Product number Packaging Price Buy
L4206 100ml $74.2 Buy
L0068 25mL $18 Buy
L0068 500mL $166 Buy
TRC-L478040-5G 5g $84 Buy
TRC-L478040-50G 50g $145 Buy

3,5-Lutidine Chemical Properties, Uses, Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

3,5-Lutidine is a reactant used in the synthesis of phthalazine and pyrazine compounds, as well as other pharmaceuticals.

Synthesis Reference(s)

Synthesis, p. 573, 1994 DOI: 10.1055/s-1994-25526

Flammability and Explosibility

Flammable

Purification Methods

Dry 3,5-lutidine with sodium and fractionally distil it through a Todd column (p 11) packed with glass helices. Dissolve (100mL) in dilute HCl (1:4) and steam distil this until 1L of distillate is collected. Excess conc NaOH is added to the residue which is again steam distilled. The base is extracted from the distillate, using diethyl ether. The extract is dried over K2CO3, and distilled. It is then fractionally crystallised by partial freezing. The hydrochloride has m 229o(sublimes at 190-231o), and the picrate has m 242-243o(dec, from H2O), 249-250o(dec, from AcOH). [Beilstein 20 II 161, 20 III/IV 2788, 20/6 V 60.]

Toxics Screening Level

The initial threshold screening level (ITSL) for 3,5-lutidine is 0.1 μg/m3 (annual averaging time).

3,5-Lutidine Preparation Products And Raw materials

Raw materials

Methyl vinyl sulfone

Preparation Products

3,5-Dimethylpyridin-4-amine 5-Methylpyridin-3-amine 3,5-bis(chloromethyl)pyridine Ethyl methylphosphonic acid 3-Cyano-5-methylpyridine
Methyl 5-methylnicotinate 2,3,5-Collidine 1,3,5-Trimethyl-1,2-dihydropyridin-2-one 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-(1,1-diMethylethyl)-5-Methyl- 3,5-Dimethylpiperidine
3,5-dimethylpyridine-4-carboxylic acid

1of3

3,5-Lutidine Suppliers

Global Suppliers ( 371)
Supplier Tel Email Country ProdList Advantage
Changzhou KOYE Chemical Co.,LTD. 519-81882581 18602584369 Lydia@kwchem.com China 114 58
Shanghai TongYuan Chemical Co., Ltd. 021-021-69182866 13701855675 tongyuanchem@126.com China 4184 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing dtftchem Technology Co., Ltd. 010-60275820 13031183356 elainezt@sina.com China 1386 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Supplier Advantage
Changzhou KOYE Chemical Co.,LTD. 58
Shanghai TongYuan Chemical Co., Ltd. 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Beijing dtftchem Technology Co., Ltd. 62
Energy Chemical 61
Jia Xing Isenchem Co.,Ltd 66
Shanghai Hanhong Scientific Co.,Ltd. 64
Shandong Xiya Chemical Co., Ltd 57

View Latest Price from 3,5-Lutidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-Lutidine pictures 2026-09-17 3,5-Lutidine
591-22-0
 1KG 99.0% 1000kg/month WUHAN FORTUNA CHEMICAL CO., LTD
3,5-Lutidine pictures 2026-08-20 3,5-Lutidine
591-22-0
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
3,5-Lutidine pictures 2020-11-16 3,5-Lutidine
591-22-0
 $5.00 10Kg/Bag 99% 20 Tons Longyan Tianhua Biological Technology Co., Ltd
  • 3,5-Lutidine pictures
  • 3,5-Lutidine
    591-22-0
  • $0.00
  • 99.0%
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • 3,5-Lutidine pictures
  • 3,5-Lutidine
    591-22-0
  • $1.10
  • 99.00%
  • Dideu Industries Group Limited
  • 3,5-Lutidine pictures
  • 3,5-Lutidine
    591-22-0
  • $5.00
  • 99%
  • Longyan Tianhua Biological Technology Co., Ltd

3,5-Lutidine Spectrum

3,5-Lutidine(591-22-0)MS3,5-Lutidine(591-22-0)13CNMR3,5-Lutidine(591-22-0)IR13,5-Lutidine(591-22-0)IR23,5-Lutidine(591-22-0)Raman3,5-Lutidine(591-22-0)ESR

591-22-0 (3,5-Lutidine ) Related Search:

3-Aminopyridine Poly(dimethylsiloxane) 2-Chloro-3-cyanopyridine Dimethyl sulfoxide N,N-Dimethylformamide
2,6-Lutidine Diethyl pyridine-3,5-dicarboxylate Esomeprazole 2-ethyl-3,5-dimethylpyridine 2,5-LUTIDINE 98+%,2,5-DIMETHYLPYRIDINE, 2,5-LUTIDINE
5,6,7,8-tetrahydro-3-methylquinoline 3,4-Lutidine 2,4-Lutidine Diethyl 2,6-dimethyl-3,5-pyridinedicarboxylate 5-Ethylpyridine-2,3-dicarboxylic acid
Pyridinitril 3,5-Diethyl-2-n-propylpyridine 2,3-Lutidine

1of4

pyridine,3,5-dimethyl- Lutidine,98% 3 5-LUTIDINE STANDARD FOR GC 3,5-LUTIDINE, 98+% 3,5-DIMETHYLPYRIDINE 98+% 3,5-Dimetylpyridine 3,5-Lutidine,99% 3,5-dimethyl-pyridin 3,5-Lutidine, 98+% 100ML 3,5-LUTIDINE 3,5-DIMETHYLPYRIDINE 3,5-diMethyl pyridine cation 3,5-DIMETHYLPYRIDINE FOR SYNTHESIS 3,5-two Methyl pyridine 35L 3,5-LUTIDINE Loratadine Impurity 27 3,5-Lutidine> Nicotine Related Compound 2 3,5-Lutidine ISO 9001：2015 REACH 3,5-dimethhylpyridine 3,5-LUTIDINE For Synthesis Nicotine Impurity 6 3, 5-Lutidine 98% For Synthesis 3,5-DIMETHYLPYRIDINE 591-22-0 242-08-6 Reagents for Oligosaccharide Synthesis Building Blocks Analytical Standards Alphabetic Analytical Chromatography Product Catalog C7 and C8 Pyridines Heterocyclic Building Blocks Biochemistry Reagents for Oligosaccharide Synthesis Pyridines derivates Heterocyclic Compounds K00001