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5-Iodocytidine

5-Iodocytidine Structure
5-Iodocytidine structure
CAS No.
1147-23-5
Chemical Name:
5-Iodocytidine
Synonyms
5-IC;5-I-Cr;iodocytidine;5-IODOCYTIDINE;5-Iodo-D-cytidine;Cytidine, 5-iodo-;5-IODOCYTIDINE,99+%;5-lodo-cytidine(5-I-Cr);5-Iodocytidine USP/EP/BP;1-D-Ribofuranosyl-5-iodocytosine
CBNumber:
CB4422468
Molecular Formula:
C9H12IN3O5
Molecular Weight:
369.11
MDL Number:
MFCD00056070
MOL File:
1147-23-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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5-Iodocytidine Properties

Melting point >160°C (dec.)
Boiling point 565.5±60.0 °C(Predicted)
Density 2.52±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka 13.48±0.70(Predicted)
form Crystalline or Powder
color White to Off-white
Sensitive Light Sensitive
Stability Light Sensitive
InChI InChI=1S/C9H12IN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1
InChIKey LQQGJDJXUSAEMZ-UAKXSSHOSA-N
SMILES OC[C@H]1O[C@@H](N2C=C(I)C(N)=NC2=O)[C@H](O)[C@@H]1O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Safety Statements  24/25
HS Code  29389090

5-Iodocytidine price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological I8447-36 5-Iodocytidine (1-ß-D-Ribofuranosyl-5-iodocytosine) 1147-23-5 100mg $319 2026-06-03 Buy
Usbiological 296192 5-Iodocytidine Asreported 1147-23-5 1g $319 2026-06-03 Buy
Usbiological 296192 5-Iodocytidine Asreported 1147-23-5 2g $446 2026-06-03 Buy
Usbiological 296192 5-Iodocytidine Asreported 1147-23-5 5g $638 2026-06-03 Buy
Usbiological 296192 5-Iodocytidine Asreported 1147-23-5 10g $814 2026-06-03 Buy
Product number Packaging Price Buy
I8447-36 100mg $319 Buy
296192 1g $319 Buy
296192 2g $446 Buy
296192 5g $638 Buy
296192 10g $814 Buy

5-Iodocytidine Chemical Properties, Uses, Production

Chemical Properties

White powder

Uses

5-Iodocytidine is an intermediate for research in the field of nucleic acids and nucleic acid-protein interactions

Synthesis

Cytidine

65-46-3

5-Iodocytidine

1147-23-5

Synthesis of 5-iodocytidine 191: Cytidine 190 (15.0 g, 61.7 mmol) was dissolved in a mixed solvent of 225 mL of acetic acid and 225 mL of carbon tetrachloride, and heated to 40 °C. Subsequently, iodine (9.6 g, 75.7 mmol) was added. A solution prepared from iodic acid (9.6 g, 54.6 mmol) dissolved in 25 mL of water was added slowly dropwise with stirring, and the time of dropwise addition was controlled within 10 minutes. The reaction mixture was stirred continuously at 40 °C for 6 h, followed by stirring at room temperature overnight. The reaction process was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was concentrated under reduced pressure. The crude product was purified by fast chromatography on silica gel columns, using a gradient elution of dichloromethane-methanol (15:1 to 10:1 to 5:1), resulting in 19.4 g (85.1% yield) of the target product 5-iodocytidine (191).

References

[1] Patent: WO2015/196130, 2015, A2. Location in patent: Page/Page column 634; 635
[2] Patent: WO2015/196128, 2015, A2. Location in patent: Page/Page column 642
[3] Patent: EP2918275, 2015, A1. Location in patent: Paragraph 2219; 2220
[4] Patent: EP2918275, 2016, B1. Location in patent: Paragraph 2219; 2220
[5] Journal of the American Chemical Society, 2015, vol. 137, # 1, p. 34 - 37

5-Iodocytidine synthesis

65-46-3
1147-23-5
Synthesis of 5-Iodocytidine from Cytidine

5-Iodocytidine Preparation Products And Raw materials

Raw materials

Cytidine Acetic acid Carbon tetrachloride Iodic acid Water
iodine

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Preparation Products

5-Iodocytidine Suppliers

Global Suppliers ( 141)
Supplier Tel Email Country ProdList Advantage
Shanghai Xuanheng Pharmaceutical Technology Co., LTD 18202133986 wangweijun21@sohu.com China 473 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Hongene Biotech Corporation 021-64757213 info@hongene.com China 672 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
Supplier Advantage
Shanghai Xuanheng Pharmaceutical Technology Co., LTD 58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Hongene Biotech Corporation 61
Capot Chemical Co., Ltd 66
Adamas Reagent, Ltd. 59
Chemsky (shanghai) International Co.,Ltd 60
Hunan Hui Bai Shi Biotechnology Co., Ltd. 62
T&W GROUP 58
Beijing HuaMeiHuLiBiological Chemical 58

View Latest Price from 5-Iodocytidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Iodocytidine pictures 2026-09-17 5-Iodocytidine
1147-23-5
 100g 98%min 100kgs WUHAN FORTUNA CHEMICAL CO., LTD
5-Iodocytidine pictures 2026-08-13 5-Iodocytidine
1147-23-5
 1G 98% 2000 Shenzhen Nexcon Pharmatechs Ltd.
5-Iodocytidine pictures 2026-07-15 5-Iodocytidine
1147-23-5
 99.99% 10g TargetMol Chemicals Inc.

5-Iodocytidine Spectrum

5-Iodocytidine(1147-23-5)1HNMR

1147-23-5 (5-Iodocytidine) Related Search:

5-Bromocytidine Cytidine-5'-triphosphate disodium salt dihydrate 1-beta-D-Arabinofuranosylcytosine hydrochloride 5-Azacytidine Cytarabine
5-Bromouridine Cytidine 2''-DEOXY-5-IODOCYTIDINE (5-IODO-2''-DEOXYCYTIDINE: 5-IDC),2'-DEOXY-5-IODOCYTIDINE 5-Iodocytosine 2''-Deoxy-2''-fluoro-5-iodocytidine
N4-Diisobutylaminomethylidene-5'-O-(dimethoxytrityl)-5-iodo-2'-O-methylcytidine 5-Iodo-2'-O-methylcytidine N4-(Diisobutylaminomethylidene)-5-iodo-2'-O-methyl-cytidine 5-Iodocytidine 5-Iodocytidine, HPLC purified, 98% pure with HPLC UV chromatogram
5-Iodocytidine-5'-triphosphate lithium salt 2'-Deoxy-2'-methylene-5-iodocytidine 3'-Deoxy-5-iodocytidine

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1-BETA-D-RIBOFURANOSYL-5-IODOCYTOSINE 1-D-Ribofuranosyl-5-iodocytosine 5-Iodo-D-cytidine iodocytidine 5-IODOCYTIDINE,99+% 5-IC 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-iodo-pyrimidin-2-one 4-azanyl-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-pyrimidin-2-one 4-aMino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyriMidin-2-one 4-AMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-iodopyriMidin-2(1H)-one 5-IODOCYTIDINE 4-Amino-2-hydroxy-5-iodo-1β-D-ribofuranosylpyrimidine 5-I-Cr Cytidine, 5-iodo- 5-Iodocytidine USP/EP/BP 5-lodo-cytidine(5-I-Cr) 1147-23-5 C9H12IN3O5 5-FOA Bases & Related Reagents Nucleotides Nucleosides-5-I Nucleosides