Trimethyl thiazole
- CAS No.
- 13623-11-5
- Chemical Name:
- Trimethyl thiazole
- Synonyms
- 2,4,5-TRIMETHYLTHIAZOLE;FEMA 3325;Thiazole, 2,4,5-trimethyl-;2,4,5-Trimethylthiazole ,99%;219185-5G;FEMA NUMBER 3325;TRIMETHYLTHIAZOLE;Thiazole, trimethyl-;triMethyl-1,3-thiazole;2,4,5-TRIMETHYLANILINE
- CBNumber:
- CB4422716
- Molecular Formula:
- C6H9NS
- Molecular Weight:
- 127.21
- MDL Number:
- MFCD00005332
- MOL File:
- 13623-11-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | -32.4°C |
|---|---|
| Boiling point | 166-167 °C/717 mmHg (lit.) |
| Density | 1.013 g/mL at 25 °C (lit.) |
| refractive index |
n |
| FEMA | 3325 | 2,4,5-TRIMETHYLTHIAZOLE |
| FLAVIS Number | 15.019 | 2,4,5-Trimethylthiazole |
| Flash point | 133 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | pK1:4.55 (25°C,μ=0.1) |
| form | liquid |
| Specific Gravity | 1.311.013 |
| color | Light orange to Yellow to Green |
| Odor | at 1.00 % in dipropylene glycol. musty nutty vegetable cocoa hazelnut chocolate coffee |
| Odor Type | chocolate |
| biological source | synthetic |
| JECFA Number | 1036 |
| BRN | 107148 |
| Major Application | flavors and fragrances |
| InChI | 1S/C6H9NS/c1-4-5(2)8-6(3)7-4/h1-3H3 |
| InChIKey | BAMPVSWRQZNDQC-UHFFFAOYSA-N |
| SMILES | Cc1nc(C)c(C)s1 |
| LogP | 2.02 |
| CAS DataBase Reference | 13623-11-5(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | 2,4,5-TRIMETHYLTHIAZOLE |
| FDA UNII | 6393273PE0 |
| NIST Chemistry Reference | Thiazole, 2,4,5-trimethyl-(13623-11-5) |
| EPA Substance Registry System | Thiazole, trimethyl- (13623-11-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() ![]() GHS02,GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H302-H315-H318-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-37/38-41-36/37/38 | |||||||||
| Safety Statements | 26-39-37/39-36-7/9 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3.2 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Flam. Liq. 3 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
Trimethyl thiazole price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W332518 | 2,4,5-Trimethylthiazole ≥98%, FG | 13623-11-5 | 1 each | $55.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | W332518 | 2,4,5-Trimethylthiazole ≥98%, FG | 13623-11-5 | 25g | $105 | 2026-04-30 | Buy |
| Sigma-Aldrich | W332518 | 2,4,5-Trimethylthiazole ≥98%, FG | 13623-11-5 | 100g | $229 | 2026-04-30 | Buy |
| Sigma-Aldrich | W332518 | 2,4,5-Trimethylthiazole ≥98%, FG | 13623-11-5 | 1kg | $1440 | 2026-04-30 | Buy |
| Sigma-Aldrich | 219185 | 2,4,5-Trimethylthiazole 98% | 13623-11-5 | 5g | $41.9 | 2026-04-30 | Buy |
Trimethyl thiazole Chemical Properties, Uses, Production
Description
2,4,5-trimethyl thiazole has a cocoa, dark chocolate, nutty, coffee note. It is naturally found in cooked potatoes, cooked meat, coffee, black tea, and herbs. It is used as a flavor ingredient in foods.
References
[1] George A. Burdock, Encyclopedia of Food and Color Additives, Volume 3, 1997
[2] Erich Ziegler and Herta Ziegler, Flavourings: Production, Composition, Applications, Regulations, 1998
Chemical Properties
clear colourless to yellow liquid
Chemical Properties
2,4,5-Trimethyl thiazole has a cocoa, dark chocolate, nutty, coffee taste.
Occurrence
Reported found in kohlrabi, French fried potato, boiled and cooked potato, fried chicken, raw chicken, boiled and cooked beef, grilled and roasted beef, lamb and mutton liver, boiled and cooked cured pork, coffee, black tea, coriander seed, katsuobushi (dried bonito), cooked shrimp and other natural sources.
Uses
2,4,5-Trimethylthiazole was employed as internal standard in the gas chromatographic determination of aldehydes in alcoholic beverages.
Preparation
By decarboxylation of 2,4-dimethylthiazole-5-acetic acid; by reacting acetamide and phosphorous pentasulfide with methyl-α-bromoethyl ketone.
Definition
ChEBI: A 1,3-thiazole that is thiazole in which all three hydrogens are replaced by methyl groups. A Maillard reaction product, it is a flavour component in many cooked foods, including cooked meats and potatoes.
Aroma threshold values
Detection: 50 ppb
Taste threshold values
Taste characteristics at 10 ppm: nutty, cocoa and green vegetative-like with roasted earthy nuances.
General Description
2,4,5-Trimethylthiazole is a volatile oxidant and was isolated during microwave-induced L-cysteine/D-glucose Maillard model system.
Trimethyl thiazole Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| jiliang chemicals | 21-62165282 | bidingchem@163.com | China | 1395 | 60 |
View Latest Price from Trimethyl thiazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-30 | Trimethyl thiazole
13623-11-5
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
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2026-05-28 | Trimethyl thiazole
13623-11-5
|
$1.00 | 1KG | 99% | 50 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
![]() |
2025-05-23 | Trimethyl thiazole
13623-11-5
|
$50.00 | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co Ltd |
-

- Trimethyl thiazole
13623-11-5
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-

- Trimethyl thiazole
13623-11-5
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-

- Trimethyl thiazole
13623-11-5
- $50.00
- 99
- Hebei Zhuanglai Chemical Trading Co Ltd
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