Milnacipran Hydrochloride
- CAS No.
- 101152-94-7
- Chemical Name:
- Milnacipran Hydrochloride
- Synonyms
- IXEL;F 2207;TOLEDOMIN;Dalcipran;cis-(+-)-d;MIDALCIPRAN;MLNACIPRAM HCL;Chiral Reagents;Milnacipran HCI;MILNACIPRAN HCL
- CBNumber:
- CB4423243
- Molecular Formula:
- C15H23ClN2O
- Molecular Weight:
- 282.81
- MDL Number:
- MFCD00901293
- MOL File:
- 101152-94-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 179-1810C |
|---|---|
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | H2O: 19 mg/mL |
| form | solid |
| color | white |
| Water Solubility | H2O: 19mg/mL |
| Merck | 14,6194 |
| InChI | InChI=1/C15H22N2O.ClH/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12;/h5-9,13H,3-4,10-11,16H2,1-2H3;1H/t13-,15+;/s3 |
| InChIKey | XNCDYJFPRPDERF-DPKVYHSMNA-N |
| SMILES | [C@@]1(C(=O)N(CC)CC)(C[C@H]1CN)C1C=CC=CC=1.Cl |&1:0,9,r| |
| CAS DataBase Reference | 101152-94-7(CAS DataBase Reference) |
| FDA UNII | RNZ43O5WW5 |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 7-16-36/37-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GZ1014010 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29242990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral | |||||||||
| Toxicity | LD50 orally in mice: 237 mg/kg (Bonnaud) | |||||||||
| NFPA 704 |
|
Milnacipran Hydrochloride price More Price(80)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M-145 | Milnacipran hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 101152-94-7 | 1mL | $227 | 2026-04-30 | Buy |
| Sigma-Aldrich | M1318 | Milnacipran hydrochloride ≥98% (HPLC), solid | 101152-94-7 | 10mg | $267 | 2026-04-30 | Buy |
| Sigma-Aldrich | M1318 | Milnacipran hydrochloride ≥98% (HPLC), solid | 101152-94-7 | 50mg | $821.95 | 2026-04-30 | Buy |
| TCI Chemical | M2133 | Milnacipran Hydrochloride >98.0%(HPLC)(T) | 101152-94-7 | 50mg | $17 | 2026-04-30 | Buy |
| TCI Chemical | M2133 | Milnacipran Hydrochloride >98.0%(HPLC)(T) | 101152-94-7 | 500mg | $80 | 2026-04-30 | Buy |
Milnacipran Hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
Milnacipran Hydrochloride is an antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.
Definition
ChEBI: Milnacipran hydrochloride is a member of acetamides.
General Description
Milnacipran Hydrochloride, sold under the brand names Savella, Ixel, Dalcipran, or Toledomin, is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the treatment of depression. In 2009, the US Food and Drug Administration (FDA) approved milnacipran for management of the chronic pain disorder fibromyalgia, making it only the third drug approved in the US for this indication besides duloxetine and pregabalin.
Biological Activity
Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo .
Biochem/physiol Actions
Serotonin and norepinephrine reuptake inhibitor (SNRI)
storage
+4°C
Milnacipran Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Modern Pharmaceutical Co., Ltd | -- | xujin3@sinopharm.com | China | 46 | 38 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
View Lastest Price from Milnacipran Hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Milnacipran Hydrochloride
101152-94-7
|
1kg | 0.99 | 1000kg | Shaanxi Xianhe Biotech Co., Ltd | ||
 |
2026-07-27 | Milnacipran hydrochloride
101152-94-7
|
$31.00-81.00 | 99.92% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | Milnacipran hydrochloride
101152-94-7
|
$31.00-81.00 | 99.92% | 10g | TargetMol Chemicals Inc. |
-
- Milnacipran Hydrochloride
101152-94-7
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- Milnacipran hydrochloride
101152-94-7
- $31.00-81.00
- 99.92%
- TargetMol Chemicals Inc.
-
- Milnacipran hydrochloride
101152-94-7
- $31.00-81.00
- 99.92%
- TargetMol Chemicals Inc.
