DL-Homocysteinethiolactone hydrochloride
- CAS No.
- 6038-19-3
- Chemical Name:
- DL-Homocysteinethiolactone hydrochloride
- Synonyms
- DL-HOMOCYSTEINE THIOLACTONE HYDROCHLORIDE;DL-HOMOCYSTEINE THIOLACTONE HCL;DL-HCT;hctlhydrochloride;TIMTEC-BB SBB004035;DL-Homocysteinethiol;3-aminothiolan-2-one;Erdosteine Impurity 7 (HCl);1,4-thiolactone hydrochloride;DL-HOMOCYSTEIN THIOLACTONE HCL
- CBNumber:
- CB4429407
- Molecular Formula:
- C4H8ClNOS
- Molecular Weight:
- 153.63
- MDL Number:
- MFCD00012724
- MOL File:
- 6038-19-3.mol
- MSDS File:
- SDS
| Melting point | 202 °C (dec.)(lit.) |
|---|---|
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Fine Crystalline Powder |
| color | White |
| Water Solubility | 740.5 g/L (20 C) |
| Merck | 14,4734 |
| BRN | 3562103 |
| InChI | InChI=1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H |
| InChIKey | ZSEGSUBKDDEALH-UHFFFAOYSA-N |
| SMILES | C1(N)CCSC1=O.Cl |
| CAS DataBase Reference | 6038-19-3(CAS DataBase Reference) |
| FDA UNII | 5D8467GAGD |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XN1928400 | |||||||||
| F | 1-8-9 | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
DL-Homocysteinethiolactone hydrochloride price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 53530 | DL-Homocysteine thiolactone hydrochloride ≥99.0% (AT) | 6038-19-3 | 25g | $47.3 | 2024-03-01 | Buy |
| TCI Chemical | H0646 | DL-Homocysteinethiolactone Hydrochloride >98.0%(T) | 6038-19-3 | 25g | $26 | 2025-07-31 | Buy |
| Usbiological | H7001 | DL-Homocysteine Thiolactone Hydrochloride | 6038-19-3 | 25g | $312 | 2021-12-16 | Buy |
| Usbiological | 278950 | dlHomocysteine thiolactone hydrochloride | 6038-19-3 | 25g | $325 | 2021-12-16 | Buy |
| SynQuest Laboratories | 8H70-5-Z1 | DL-Homocysteine thiolactone hydrochloride | 6038-19-3 | 100g | $77 | 2021-12-16 | Buy |
DL-Homocysteinethiolactone hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Powder
Uses
DL-Homocysteine thiolactone hydrochloride is used as an intermediate of erdosteine and citiolone.
General Description
DL-Homocysteine thiolactone hydrochloride (HTL-HCl) is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.
Synthesis
454-29-5
6038-19-3
The general procedure for the synthesis of DL-homocysteine thiolactone hydrochloride from DL-homocysteine was as follows: 100 g of DL-methionine was added to a 3-liter cryogenic autoclave pre-cooled to -40°C in a dry ice-acetonitrile solvent mixture, followed by the slow addition of dry ammonia until DL-methionine in the concentrated liquid ammonia was completely dissolved. At a reaction temperature of -35 to -40°C, 60 g of chopped sodium metal was added in batches and the reaction process was followed by liquid chromatography. Upon completion of the reaction, stirring was stopped, the reaction mixture was allowed to stand, and the upper clear night layer was carefully transferred to another three-necked flask. Ammonium chloride was added to quench the reaction and the reaction mixture was allowed to warm up naturally to room temperature until ammonia was completely spilled. The resulting solid was a mixture of DL-homocysteine sodium salt, sodium chloride and ammonium chloride. Treatment by a cation exchange resin to remove sodium ions and subsequent adjustment of the eluate to pH 1 with concentrated hydrochloric acid resulted in 81 g of DL-homocysteine thiolactone hydrochloride in 79% yield.
References
[1] Patent: CN107325073, 2017, A. Location in patent: Paragraph 0018; 0019; 0020; 0021; 0022; 0023; 0024-0034
DL-Homocysteinethiolactone hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| EAST STAR BIOTECH (SUZHOU) CO., LTD. | +8617706846989 | marketing@eaststarbio.com | China | 48 | 58 |
| DONBOO AMINO ACID COMPANY | +8618051385538 | donboo@donboo.com | China | 9363 | 58 |
| Wuhan BJM Pharm Inc | 027-52341919 13545198479 | sales03@benjaminpharmchem.com | China | 584 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | sales@hbmojin.com | China | 12320 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Moxin Chemicals | +86-17320513646 +8617320513646 | anna@molcoo.com | China | 9893 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
View Lastest Price from DL-Homocysteinethiolactone hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-18 | DL-Homocysteinethiolactone hydrochloride
6038-19-3
|
US $0.00-0.00 / kg | 1kg | 98.5%min HPLC | 5000kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-09-15 | DL-Homocysteine thiolactone hydrochloride
6038-19-3
|
US $29.00 / mL | ≥95% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-08-08 | DL-Homocysteinethiolactone hydrochloride
6038-19-3
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd |
-
- DL-Homocysteinethiolactone hydrochloride
6038-19-3
- US $0.00-0.00 / kg
- 98.5%min HPLC
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- DL-Homocysteine thiolactone hydrochloride
6038-19-3
- US $29.00 / mL
- ≥95%
- TargetMol Chemicals Inc.
-
- DL-Homocysteinethiolactone hydrochloride
6038-19-3
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
