ChemicalBook >> CAS DataBase List >>eIF4A3 inhibitor 53a
eIF4A3 inhibitor 53a
- CAS No.
- 2095486-67-0
- Chemical Name:
- eIF4A3 inhibitor 53a
- Synonyms
- eIF4A3-IN-1;eIF4A3 inhibitor 53a;eIF4A3-IN-1 (compound 53a);eIF4A3 IN 1,eIF4A3IN1,eIF-4A3-IN-1;Benzonitrile, 3-[4-[[(3S)-4-(4-bromobenzoyl)-3-(4-chlorophenyl)-1-piperazinyl]carbonyl]-5-methyl-1H-pyrazol-1-yl]-
- CBNumber:
- CB44667872
- Molecular Formula:
- C29H23BrClN5O2
- Molecular Weight:
- 588.88
- MDL Number:
- MFCD32174248
- MOL File:
- 2095486-67-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-04-24 14:59:00
eIF4A3 inhibitor 53a price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | VID48667 | Eif4A3-in-1 | 2095486-67-0 | 1mg | $250 | 2026-06-05 | Buy |
| Biosynth | VID48667 | Eif4A3-in-1 | 2095486-67-0 | 5mg | $674.95 | 2026-06-05 | Buy |
| Biosynth | VID48667 | Eif4A3-in-1 | 2095486-67-0 | 10mg | $1079.9 | 2026-06-05 | Buy |
| Biosynth | VID48667 | Eif4A3-in-1 | 2095486-67-0 | 25mg | $2025 | 2026-06-05 | Buy |
| Biosynth | VID48667 | Eif4A3-in-1 | 2095486-67-0 | 50mg | $3239.5 | 2026-06-05 | Buy |
eIF4A3 inhibitor 53a Chemical Properties, Uses, Production
Uses
eIF4A3-IN-1 (compound 53a) is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM), which binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD[1].
References
[1] Ito M, et al. Discovery of Novel 1,4-Diacylpiperazines as Selective and Cell-Active eIF4A3 Inhibitors. J Med Chem. 2017 Apr 27;60(8):3335-3351. DOI:10.1021/acs.jmedchem.6b01904
eIF4A3 inhibitor 53a Preparation Products And Raw materials
Raw materials
Preparation Products
eIF4A3 inhibitor 53a Suppliers
Global Suppliers ( 26)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Suzhou Chenrui Biotechnology Co. LTD | 17625585511 | 1580084073@qq.com | China | 992 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2377 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
2095486-67-0 (eIF4A3 inhibitor 53a) Related Search:
eIF4A3-IN-1
eIF4A3 inhibitor 53a
eIF4A3-IN-1 (compound 53a)
Benzonitrile, 3-[4-[[(3S)-4-(4-bromobenzoyl)-3-(4-chlorophenyl)-1-piperazinyl]carbonyl]-5-methyl-1H-pyrazol-1-yl]-
eIF4A3 IN 1,eIF4A3IN1,eIF-4A3-IN-1
2095486-67-0
C29H23BrClN5O2
