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Remibrutinib

Remibrutinib structure

CAS No.: 1787294-07-8

Chemical Name:: Remibrutinib

Synonyms: LOU064;LOU-064;Remibrutinib (LOU064) ，S9660;N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide;Remibutinib;REMIBRUTINIB;Lou064/Remibrutinib;Remibrutinib (LOU064);Remibrutinib, 10 mM in DMSO;Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase

CBNumber:: CB44675356

Molecular Formula:: C27H27F2N5O3

Molecular Weight:: 507.53

MDL Number:: MFCD32215329

MOL File:: 1787294-07-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-27 17:00:41

Product description	Number	Pack Size	Price
Remibrutinib ≥98%	44962	5mg	$69
Remibrutinib ≥98%	44962	10mg	$117
Remibrutinib ≥98%	44962	25mg	$207
Remibrutinib 99.76%	CS-0103905	1mg	$180
Remibrutinib 99.76%	CS-0103905	5mg	$379

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Remibrutinib Properties

Boiling point	634.8±55.0 °C(Predicted)
Density	1.332±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: 125 mg/mL (246.29 mM)
pka	11.67±0.70(Predicted)
form	Solid
color	White to off-white
InChIKey	CUABMPOJOBCXJI-UHFFFAOYSA-N
SMILES	C(NC1=CC(F)=CC(C2C(OCCN(C)C(=O)C=C)=C(N)N=CN=2)=C1C)(=O)C1=CC=C(C2CC2)C=C1F
FDA UNII	I7MVZ8HDNU

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H317-H334
Precautionary statements	P304+P341-P342+P311-P302+P352-P333+P313-P321-P261-P272-P280-P261-P285-P363-P501

Remibrutinib price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	44962	Remibrutinib ≥98%	1787294-07-8	5mg	$69	2026-04-30	Buy
Cayman Chemical	44962	Remibrutinib ≥98%	1787294-07-8	10mg	$117	2026-04-30	Buy
Cayman Chemical	44962	Remibrutinib ≥98%	1787294-07-8	25mg	$207	2026-04-30	Buy
ChemScene	CS-0103905	Remibrutinib 99.76%	1787294-07-8	1mg	$180	2026-06-04	Buy
ChemScene	CS-0103905	Remibrutinib 99.76%	1787294-07-8	5mg	$379	2026-06-04	Buy

Product number	Packaging	Price	Buy
44962	5mg	$69	Buy
44962	10mg	$117	Buy
44962	25mg	$207	Buy
CS-0103905	1mg	$180	Buy
CS-0103905	5mg	$379	Buy

Remibrutinib Chemical Properties,Uses,Production

Description

Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC₅₀ value of 1 nM. Remibrutinib inhibits BTK activity with an IC₅₀value of 0.023 μM in blood. Remibrutinib has the potential for Chronic urticaria (CU) treatment.

Chemical Properties

White to off-white Solid

Uses

Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood[1]. Remibrutinib has the potential for Chronic urticaria (CU) treatment[2].

References

[1] Daniela Angst, et al. Novel amino pyrimidine derivatives. Patent WO2015079417A1.
[2] Kolkhir P, et al. New treatments for chronic urticaria. Ann Allergy Asthma Immunol. 2019 Aug 23. DOI:10.1016/j.anai.2019.08.014

Remibrutinib Preparation Products And Raw materials

Raw materials

Preparation Products

Remibrutinib Suppliers

Global( 101)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou ARTK Medchem Co., Ltd.	+86-18168183658	sales1@artkmedchem.com	China	39007	58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.	+86-18600796368	sales@sjar-tech.com	China	556	58
Zison Pharmaceutical (Shandong) Co., Ltd.	+86-0086-531-88259693 +86-18660188356	tracy.li@zisonpharm.com	China	88	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19935	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1059@dideu.com	China	29096	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6378	58
Shanghai Joiny Pharmaceutical Co.,LTD	+86-13681955282	gyd@joiny-pharma.com	China	401	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +86-15965530500	nickzhang@hangyubiotech.com	China	9935	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58

Supplier	Advantage
Suzhou ARTK Medchem Co., Ltd.	58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.	58
Zison Pharmaceutical (Shandong) Co., Ltd.	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
InvivoChem	58
Shanghai Joiny Pharmaceutical Co.,LTD	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Aladdin Scientific	58

View Lastest Price from Remibrutinib manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-18	Remibrutinib 1787294-07-8		1g	More Than 99%	100kg/Month	BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
2026-07-27	Remibrutinib 1787294-07-8	$98.00-378.00		99.74%	10g	TargetMol Chemicals Inc.
2026-07-24	Remibrutinib 1787294-07-8		1kg	98%	1000kgs	Shaanxi Dideu New Materials Co. Ltd

Remibrutinib
1787294-07-8
$0.00
More Than 99%
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Remibrutinib
1787294-07-8
$98.00-378.00
99.74%
TargetMol Chemicals Inc.

Remibrutinib
1787294-07-8
$0.00
98%
Shaanxi Dideu New Materials Co. Ltd

Remibrutinib Spectrum

Remibrutinib(1787294-07-8)¹HNMR

1787294-07-8(Remibrutinib)Related Search:

Carbamic acid, N-[2-[[4-amino-6-[3-[(4-cyclopropyl-2-fluorobenzoyl)amino]-5-fluoro-2-methylphenyl]-5-pyrimidinyl]oxy]ethyl]-N-methyl-, 1,1-dimethylethyl ester Remibrutinib Benzamide, N-[3-[6-amino-5-[2-(methylamino)ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro- AVL-292 GDC-0853

BMS-986142

1of2

REMIBRUTINIB N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide Benzamide, N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro- Remibrutinib (LOU064) Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase N-[3-[6-Amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide Remibrutinib, 10 mM in DMSO Lou064/Remibrutinib LOU064 LOU-064 N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide Remibrutinib (LOU064) ，S9660 Remibutinib 1787294-07-8 C27H27F2N5O3 chemical