ChemicalBook >> CAS DataBase List >>RGX-104 free Acid
RGX-104 free Acid
- CAS No.
- 610318-54-2
- Chemical Name:
- RGX-104 free Acid
- Synonyms
- SB742881;RGX-104 free Acid;RGX-104 (free form);RGX-104, 10 mM in DMSO;Abequolixron (RGX-104);RGX-104freeAcid/SB742881;610318-54-2 (FREE FORM) 610318-03-1 (HCL);RGX 104,inhibit,LXR,RGX-104,Liver X receptor,RGX104,Inhibitor;(R)-2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)butoxy)phenyl)acetic acid;Benzeneacetic acid, 3-[(3R)-3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]butoxy]-
- CBNumber:
- CB44808622
- Molecular Formula:
- C34H33ClF3NO3
- Molecular Weight:
- 596.08
- MDL Number:
- MFCD31726291
- MOL File:
- 610318-54-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 03:30:28
| Boiling point | 677.1±55.0 °C(Predicted) |
|---|---|
| Density | 1.246±0.06 g/cm3(Predicted) |
| storage temp. | 4°C, protect from light |
| solubility | DMSO:100.0(Max Conc. mg/mL);167.76(Max Conc. mM) |
| pka | 4.19±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| InChIKey | ZLJZDYOBXVOTSA-XMMPIXPASA-N |
| SMILES | C1(CC(O)=O)=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C2=CC=CC=C2)C2=CC=CC=C2)C)=C1 |
| FDA UNII | Q26B92650V |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
RGX-104 free Acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 42120 | RGX-104 ≥98% | 610318-54-2 | 5mg | $109 | 2026-04-30 | Buy |
| Cayman Chemical | 42120 | RGX-104 ≥98% | 610318-54-2 | 10mg | $196 | 2026-04-30 | Buy |
| Cayman Chemical | 42120 | RGX-104 ≥98% | 610318-54-2 | 25mg | $382 | 2026-04-30 | Buy |
| Cayman Chemical | 42120 | RGX-104 ≥98% | 610318-54-2 | 50mg | $545 | 2026-04-30 | Buy |
| Biosynth | KZA31854 | RGX-104 free Acid | 610318-54-2 | 25mg | $1345.25 | 2026-06-04 | Buy |
RGX-104 free Acid Chemical Properties, Uses, Production
Uses
RGX-104 is combination of a liver X receptor β agonist and GITR modulator for treatment of cancer.Liver X receptor beta agonist.
in vivo
Oral administration of RGX-104 (100 mg/kg, daily) to animals bearing palpable tumors significantly suppresses the growth of multiple cancer types. Co-administration of RGX-104 with anti-PD-1 is superior to administration of either RGX-104 or anti-PD-1 alone. Importantly, co-administration of RGX-104 with anti-PD-1 therapy is well tolerated by mice, with no overt signs of toxicity[1].
| Animal Model: | NOD SCID or RAG mice injected with 1×106 SKOV3 ovarian cancer cells[1]. |
| Dosage: | 100 mg/kg. |
| Administration: | Oral administration daily for about 60 days. |
| Result: | Robustly suppressed tumor growth and progression. |
RGX-104 free Acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 47)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| InvivoChem | 13549236410 | sales@invivochem.cn | China | 6745 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2970 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9699 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| Wuxi Donghe Pharmaceutical Technology Co., Ltd. | 63313187 15358055255 | 63313187@qq.com | China | 1982 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
610318-54-2 (RGX-104 free Acid) Related Search:
RGX-104 free Acid
610318-54-2 (FREE FORM) 610318-03-1 (HCL)
RGX-104 (free form)
SB742881
Benzeneacetic acid, 3-[(3R)-3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]butoxy]-
RGX-104freeAcid/SB742881
Abequolixron (RGX-104)
(R)-2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)butoxy)phenyl)acetic acid
RGX 104,inhibit,LXR,RGX-104,Liver X receptor,RGX104,Inhibitor
RGX-104, 10 mM in DMSO
610318-54-2
C34H33ClF3NO3
