DBCO-PEG2-amine
- CAS No.
- 2250216-96-5
- Chemical Name:
- DBCO-PEG2-amine
- Synonyms
- DBCO-PEG2-amine
- CBNumber:
- CB44849575
- Molecular Formula:
- C25H29N3O4
- Molecular Weight:
- 435.52
- MDL Number:
- MFCD31811529
- MOL File:
- 2250216-96-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| DBCO-PEG2-amine | AQD21696 | 5mg | $900 |
| DBCO-PEG2-amine | AQD21696 | 50mg | $900 |
| DBCO-PEG2-amine | AQD21696 | 2mg | $900 |
| DBCO-PEG2-amine | AQD21696 | 25mg | $900 |
| DBCO-PEG2-amine | AQD21696 | 10mg | $900 |
| Boiling point | 748.9±60.0 °C(Predicted) |
|---|---|
| Density | 1.24±0.1 g/cm3(Predicted) |
| solubility | Soluble in DMSO, DCM, DMF |
| pka | 15.14±0.46(Predicted) |
| InChI | InChI=1S/C25H29N3O4/c26-13-15-31-17-18-32-16-14-27-24(29)11-12-25(30)28-19-22-7-2-1-5-20(22)9-10-21-6-3-4-8-23(21)28/h1-8H,11-19,26H2,(H,27,29) |
| InChIKey | ILEXOUGGKQHBOX-UHFFFAOYSA-N |
| SMILES | C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCC(=O)NCCOCCOCCN |
DBCO-PEG2-amine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | AQD21696 | DBCO-PEG2-amine | 2250216-96-5 | 5mg | $900 | 2026-06-04 | Buy |
| Biosynth | AQD21696 | DBCO-PEG2-amine | 2250216-96-5 | 50mg | $900 | 2026-06-04 | Buy |
| Biosynth | AQD21696 | DBCO-PEG2-amine | 2250216-96-5 | 2mg | $900 | 2026-06-04 | Buy |
| Biosynth | AQD21696 | DBCO-PEG2-amine | 2250216-96-5 | 25mg | $900 | 2026-06-04 | Buy |
| Biosynth | AQD21696 | DBCO-PEG2-amine | 2250216-96-5 | 10mg | $900 | 2026-06-04 | Buy |
DBCO-PEG2-amine Chemical Properties,Uses,Production
Description
DBCO-PEG2-amine is a PEG linker which contains DBCO and amine moieties. The DBCO group is commonly used in copper-free Click Chemistry reactions. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases the water solubility of the compound.
Uses
DBCO-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG2-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
DBCO-PEG2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-PEG2-amine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 15616186207 | changaiwei@sinopeg.com | China | 1133 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42052 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 | |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3862 | 55 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2969 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4142 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1999 | 58 |
| Xiamen Sinopeg Biotech Co., Ltd. | 400-9189898 17359873007 | sales@sinopeg.com | China | 1003 | 58 |
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