DBCO-PEG6-amine,DBCO-PEG6-NH2
- CAS No.
- 2353409-98-8
- Chemical Name:
- DBCO-PEG6-amine,DBCO-PEG6-NH2
- Synonyms
- DBCO-PEG6-amine TFA salt;DBCO-CONH-PEG6-CH2CH2NH2?TFA;DBCO-PEG6-amine,DBCO-PEG6-NH2;Dibenz[b,f]azocine-5(6H)-butanamide, N-(20-amino-3,6,9,12,15,18-hexaoxaeicos-1-yl)-11,12-didehydro-γ-oxo-
- CBNumber:
- CB15840394
- Molecular Formula:
- C33H45N3O8
- Molecular Weight:
- 611.74
- MDL Number:
- MFCD31811530
- MOL File:
- 2353409-98-8.mol
| Product description | Number | Pack Size | Price |
| DBCO-PEG6-amine 98% | bp-29788 | 50MG | $350 |
| DBCO-PEG6-amine 98% | bp-29788 | 100MG | $530 |
| DBCO-PEG6-amine 98% | bp-29788 | 250MG | $845 |
| DBCO-PEG6-amine 98% | bp-29788 | 500MG | $1375 |
| DBCO-PEG6-amine TFA salt 98% | bp-24151 | 50MG | $350 |
DBCO-PEG6-amine,DBCO-PEG6-NH2 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | bp-29788 | DBCO-PEG6-amine 98% | 2353409-98-8 | 50MG | $350 | 2026-05-24 | Buy |
| BroadPharm | bp-29788 | DBCO-PEG6-amine 98% | 2353409-98-8 | 100MG | $530 | 2026-05-24 | Buy |
| BroadPharm | bp-29788 | DBCO-PEG6-amine 98% | 2353409-98-8 | 250MG | $845 | 2026-05-24 | Buy |
| BroadPharm | bp-29788 | DBCO-PEG6-amine 98% | 2353409-98-8 | 500MG | $1375 | 2026-05-24 | Buy |
| BroadPharm | bp-24151 | DBCO-PEG6-amine TFA salt 98% | 2353409-98-8 | 50MG | $350 | 2026-05-24 | Buy |
DBCO-PEG6-amine,DBCO-PEG6-NH2 Chemical Properties,Uses,Production
Description
DBCO-PEG6-amine is a PEG linker which contains DBCO and amine moieties. The DBCO group is commonly used in copper-free Click Chemistry reactions. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases the water solubility of the compound.
Uses
DBCO-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG6-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
DBCO-PEG6-amine,DBCO-PEG6-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-PEG6-amine,DBCO-PEG6-NH2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 15616186207 | changaiwei@sinopeg.com | China | 1133 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42052 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 | |
| Nanjing Moldeep Biochemical Co., Ltd. | +86-25-58282389 +86-17351037455 | inquiries@moldeep.com | China | 19999 | 58 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14912 | 59 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3862 | 55 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4142 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1999 | 58 |
| Xiamen Sinopeg Biotech Co., Ltd. | 400-9189898 17359873007 | sales@sinopeg.com | China | 1003 | 58 |
