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6-Nitroveratryl chloroformate

CAS No.
42855-00-5
Chemical Name:
6-Nitroveratryl chloroformate
Synonyms
NVOC-CL;NVOC CHLORIDE;6-Nitroveratryl chloroformate;6-Nitroveratrylchloroformate,97%;6-NITROVERATRYL CHLOROFORMATE 97%;6-NITROVERATRYLOXYCARBONYL CHLORIDE;((nitroveratryl)oxy)chlorocarbamate;Chloroformicacid6-nitroveratrylester;4,5-DIMETHOXY-2-NITROBENZYL CHLOROFORMATE;4,5-DiMethoxy-2-nitrobenzyl chloroforMate 97%
CBNumber:
CB4487764
Molecular Formula:
C10H10ClNO6
Molecular Weight:
275.64
MDL Number:
MFCD00143507
MOL File:
42855-00-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:51

6-Nitroveratryl chloroformate Properties

Melting point 125 °C (dec.)(lit.)
Boiling point 396.4±42.0 °C(Predicted)
Density 1.399±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form solid
color Pale yellow
Water Solubility Soluble in methanol, acetone. Reacts with water.
Sensitive Moisture & Light Sensitive
BRN 2389168
Major Application peptide synthesis
InChI InChI=1S/C10H10ClNO6/c1-16-8-3-6(5-18-10(11)13)7(12(14)15)4-9(8)17-2/h3-4H,5H2,1-2H3
InChIKey RWWPKIOWBQFXEE-UHFFFAOYSA-N
SMILES C(Cl)(OCC1=CC(OC)=C(OC)C=C1[N+]([O-])=O)=O
UNSPSC Code 12352101
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  C
Risk Statements  34-37
Safety Statements  26-36/37/39-45
RIDADR  UN 3261 8/PG 2
WGK Germany  3
10-21
HazardClass  8
PackingGroup  III
HS Code  2918999090
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
Limited Quantities 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
3 0

6-Nitroveratryl chloroformate price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 420069 4,5-Dimethoxy-2-nitrobenzyl chloroformate 97% 42855-00-5 1g $245 2026-04-30 Buy
TCI Chemical D6396 4,5-Dimethoxy-2-nitrobenzyl Carbonochloridate min. 90.0 % 42855-00-5 200MG $41 2026-04-30 Buy
TCI Chemical D6396 4,5-Dimethoxy-2-nitrobenzyl Carbonochloridate min. 90.0 % 42855-00-5 1G $141 2026-04-30 Buy
Usbiological 234811 6-Nitroveratryl chloroformate 98+% (HPLC) ≥98%(HPLC) 42855-00-5 1g $240 2026-06-03 Buy
Usbiological 234811 6-Nitroveratryl chloroformate 98+% (HPLC) ≥98%(HPLC) 42855-00-5 5g $595 2026-06-03 Buy
Product number Packaging Price Buy
420069 1g $245 Buy
D6396 200MG $41 Buy
D6396 1G $141 Buy
234811 1g $240 Buy
234811 5g $595 Buy

6-Nitroveratryl chloroformate Chemical Properties, Uses, Production

Uses

4,5-Dimethoxy-2-nitrobenzyl chloroformate is used as a reagent for protection of amines, for use in N-protection of bases in nucleotide synthesis, photochemical protecting groups in organic synthesis. It is used as pharmaceutical intermediate.

Uses

4,5-Dimethoxy-2-nitrobenzyl chloroformate (NVOC-Cl) is a photolabile protecting reagent, commonly used in peptide or nucleotide synthesis to protect amines and hydroxyl groups. General applications are:

  • Preparation of inactive, caged protein conjugates which can be activated by irradiating near-ultraviolet light.
  • Solid-phase synthesis of base-sensitive S-acylthioethyl (SATE)-prooligonucleotides.
  • Modification of surface properties by introducing photocleavable NVOC moiety into chitosan to control cell attachment.

32315-10-9
1016-58-6
42855-00-5
Synthesis of 6-Nitroveratryl chloroformate from Triphosgene and 4,5-Dimethoxy-2-nitrobenzyl alcohol

6-Nitroveratryl chloroformate Preparation Products And Raw materials

Raw materials

Preparation Products

6-Nitroveratryl chloroformate Suppliers

Global Suppliers ( 76)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanQi Biotechnology Co., Ltd. +86-2332782371 +86-18120098618 sales@adobechem.com China 1250 50
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9954 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 027-65388397 18164111589 3321478047@qq.com China 2002 55
NVOC CHLORIDE NVOC-CL ((nitroveratryl)oxy)chlorocarbamate 6-NITROVERATRYL CHLOROFORMATE 97% 6-NITROVERATRYLOXYCARBONYL CHLORIDE 4,5-DIMETHOXY-2-NITROBENZYL CHLOROFORMATE Chloroformic acid 6-nitroveratryl ester~4,5-Dimethoxy-2-nitrobenzyl chloroformate~NVOC-Cl 4,5-Dimethoxy-2-nitrobenzylchloroformate~NVOC-Cl Chloroformicacid6-nitroveratrylester 6-Nitroveratrylchloroformate,97% 6-Nitroveratryl chloroformate, 6-Nitroveratryloxycarbonyl chloride, NVOC chloride, NVOC-Cl Carbonochloridic acid,(4,5-dimethoxy-2-nitrophenyl)methyl ester 4,5-Dimethoxy-2-nitrobenzyl chloroformate 95+% 4,5-Dimethoxy-2-nitrobenzyl carbonochloridoate, 6-Nitroveratryl chloroformate 4,5-DiMethoxy-2-nitrobenzyl chloroforMate 97% 2-amino-2-methylpropanoyl chloride hydrochloride (4,5-dimethoxy-2-nitrophenyl)methyl carbonochloridate (4,5-DIMETHOXY-2-NITROPHENYL)METHYL CHLOROFORMATE 6-Nitroveratryl chloroformate 42855-00-5 ClCO2CH2C6H2OCH32NO2 C10H10ClNO6 CLCO2CH2C6H2OCH32N Synthetic Reagents Others Protection and Derivatization Protecting and Derivatizing Reagents