ChemicalBook >> CAS DataBase List >>BAY-218
BAY-218
- CAS No.
- 2162982-11-6
- Chemical Name:
- BAY-218
- Synonyms
- CPD3504;BAY-218;BAY-2335218;AHR antagonist 1;BAY-218, 10 mM in DMSO;BAY-218(AHR antagonist 1);BAY2335218;BAY-2335218;BAY 2335218;BAY218;BAY 218;BAY-218;6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-[(1S)-2-hydroxy-1-methyl-ethyl]-3-oxo-pyridazine-4-carboxamide;(S)-6-(4-Chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide;6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-[(2S)-1-hydroxypropan-2-yl]-3-oxo-2,3-dihydropyridazine-4-carboxamide
- CBNumber:
- CB44908494
- Molecular Formula:
- C20H17ClFN3O3
- Molecular Weight:
- 401.82
- MDL Number:
- MOL File:
- 2162982-11-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-27 17:00:41
| Product description | Number | Pack Size | Price |
| BAY-218 ≥98% | 37583 | 5mg | $74 |
| BAY-218 ≥98% | 37583 | 10mg | $118 |
| BAY-218 ≥98% | 37583 | 25mg | $257 |
| BAY-218 ≥98% | 37583 | 50mg | $366 |
| AHR antagonist 1 | MLD98211 | 50mg | $663 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
BAY-218 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 37583 | BAY-218 ≥98% | 2162982-11-6 | 5mg | $74 | 2026-04-30 | Buy |
| Cayman Chemical | 37583 | BAY-218 ≥98% | 2162982-11-6 | 10mg | $118 | 2026-04-30 | Buy |
| Cayman Chemical | 37583 | BAY-218 ≥98% | 2162982-11-6 | 25mg | $257 | 2026-04-30 | Buy |
| Cayman Chemical | 37583 | BAY-218 ≥98% | 2162982-11-6 | 50mg | $366 | 2026-04-30 | Buy |
| Biosynth | MLD98211 | AHR antagonist 1 | 2162982-11-6 | 50mg | $663 | 2026-06-04 | Buy |
BAY-218 Chemical Properties,Uses,Production
Uses
BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses[1].
in vivo
BAY-218 (example 23) (p.o; 30 mg/kg; bid) has good anti-tumor effect combinated with aPD-L1[1].
| Animal Model: | Balb/c mice (subcutaneously CT26 cells)[1] |
| Dosage: | 30 mg/kg |
| Administration: | p.o, bid |
| Result: | Significantly decreased tumors size combinated with aPD-L1. |
References
[1] Norbert Schmees, et al. 3-oxo-2,6-diphenyl-2,3-dihydropyridazine-4-carboxamides. WO2017202816A1.
BAY-218 Preparation Products And Raw materials
Raw materials
Preparation Products
BAY-218 Suppliers
Global( 82)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11674 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +86-15965530500 | nickzhang@hangyubiotech.com | China | 9935 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 |
2162982-11-6(BAY-218)Related Search:
BAY2335218;BAY-2335218;BAY 2335218;BAY218;BAY 218;BAY-218
BAY-218
CPD3504
BAY-2335218
AHR antagonist 1
4-Pyridazinecarboxamide, 6-(4-chlorophenyl)-2-(3-fluorophenyl)-2,3-dihydro-N-[(1S)-2-hydroxy-1-methylethyl]-3-oxo-
6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-[(2S)-1-hydroxypropan-2-yl]-3-oxo-2,3-dihydropyridazine-4-carboxamide
(S)-6-(4-Chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide
BAY-218(AHR antagonist 1)
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6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-[(1S)-2-hydroxy-1-methyl-ethyl]-3-oxo-pyridazine-4-carboxamide
BAY-218, 10 mM in DMSO
2162982-11-6







