2-HYDROXYADENOSINE
- CAS No.
- 1818-71-9
- Chemical Name:
- 2-HYDROXYADENOSINE
- Synonyms
- ISOGUANOSINE;CROTONOSIDE;iso-Gr;2-Hydroxydenosine;6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one;NSC 12161;CROTONOSID;lsoguanosine;2-Oxoadenosine;ISOGUANOSINE(P)
- CBNumber:
- CB4491235
- Molecular Formula:
- C10H13N5O5
- Molecular Weight:
- 283.24
- MDL Number:
- MFCD04971989
- MOL File:
- 1818-71-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Crotonoside ≥95% (HPLC) | SMB00322 | 5mg | $400 |
| Crotonoside ≥95% (HPLC) | SMB00322 | 10mg | $643 |
| Crotonoside ≥95% | 28219 | 5mg | $72 |
| Crotonoside ≥95% | 28219 | 10mg | $101 |
| Crotonoside ≥95% | 28219 | 25mg | $233 |
| More product size | |||
| storage temp. | -20°C |
|---|---|
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | powder |
| Density | 2.25±0.1 g/cm3(Predicted) |
| Melting point | 237-241 °C(Solv: water (7732-18-5)) |
| pka | 8.25±0.40(Predicted) |
| color | White to off-white |
| Major Application |
metabolomics vitamins, nutraceuticals, and natural products |
| InChI | 1S/C10H13N5O5/c11-7-4-8(14-10(19)13-7)15(2-12-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1 |
| InChIKey | MIKUYHXYGGJMLM-UUOKFMHZSA-N |
| SMILES | NC1=NC(NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)=O |
| FDA UNII | 6V7FTE1Z1V |
| UNSPSC Code | 12352205 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280-P302+P352-P362+P364 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
2-HYDROXYADENOSINE price More Price(98)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB00322 | Crotonoside ≥95% (HPLC) | 1818-71-9 | 5mg | $400 | 2023-06-20 | Buy |
| Sigma-Aldrich | SMB00322 | Crotonoside ≥95% (HPLC) | 1818-71-9 | 10mg | $643 | 2023-01-07 | Buy |
| Cayman Chemical | 28219 | Crotonoside ≥95% | 1818-71-9 | 5mg | $72 | 2026-04-30 | Buy |
| Cayman Chemical | 28219 | Crotonoside ≥95% | 1818-71-9 | 10mg | $101 | 2026-04-30 | Buy |
| Cayman Chemical | 28219 | Crotonoside ≥95% | 1818-71-9 | 25mg | $233 | 2026-04-30 | Buy |
2-HYDROXYADENOSINE Chemical Properties,Uses,Production
Description
Crotonoside is a purine analogue that is structurally similar to pyrazole, which also inhibits the polymerase chain reaction in vitro. Crotonoside has been shown to be an inhibitor of the polymerase chain reaction in vitro, but it is unclear if this activity will translate to in vivo models.
Chemical Properties
White crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the fruit of Croton tiglium L.
Uses
2-Hydroxyadenosine is an isoquinoline alkaloid displaying anticancer activity.
Definition
ChEBI: Crotonoside is a purine nucleoside.
in vivo
Crotonoside(intraperitoneal and intravenous injection; 70 mg/kg, 35 mg/kg; once daily) induces a significant antitumor activity and inhibited xenograft tumor progress as compared to treatment with vehicle[1].
| Animal Model: | NOD-SCID mice with MV4-11 cells[1] |
| Dosage: | 70 mg/kg, 35 mg/kg |
| Administration: | Intraperitoneal and intravenous injection; 70 mg/kg, 35 mg/kg; once daily |
| Result: | Produced significant AML tumor inhibition rates of 93.5% at 70 mg/kg. |
target
Adenosine Receptor
IC 50
FLT3; HDAC3; HDAC6
2-HYDROXYADENOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 4616 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
View Lastest Price from 2-HYDROXYADENOSINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | Crotonoside
1818-71-9
|
$30.00-87.00 | 99.31% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-12 | Regadenoson Impurity 17
1818-71-9
|
10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD | ||
 |
2023-02-24 | Crotonoside
1818-71-9
|
5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Crotonoside
1818-71-9
- $30.00-87.00
- 99.31%
- TargetMol Chemicals Inc.
-
- Regadenoson Impurity 17
1818-71-9
- $0.00
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- Crotonoside
1818-71-9
- $0.00
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
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