2H-Pyrazole-3-carbaldehyde
- CAS No.
- 3920-50-1
- Chemical Name:
- 2H-Pyrazole-3-carbaldehyde
- Synonyms
- 1H-PYRAZOLE-3-CARBALDEHYDE;1H-PYRAZOLE-5-CARBALDEHYDE;PYRAZOLE-3-ALDEHYDE;Pyrazole-3-carboxaldehyde;1H-Pyrazole-3-carboxaldehyde;DKFELEX0322;3-formylpyrazole;RARECHEM AM LA 0023;3-Formyl-1H-pyrazole;Pyrazol-3-carbaldehyde
- CBNumber:
- CB4670896
- Molecular Formula:
- C4H4N2O
- Molecular Weight:
- 96.09
- MDL Number:
- MFCD06657574
- MOL File:
- 3920-50-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 149.0 to 153.0 °C |
|---|---|
| Boiling point | 300.0±13.0 °C(Predicted) |
| Density | 1.323 |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 11.20±0.10(Predicted) |
| color | White to Orange to Green |
| InChI | InChI=1S/C4H4N2O/c7-3-4-1-2-5-6-4/h1-3H,(H,5,6) |
| InChIKey | ICFGFAUMBISMLR-UHFFFAOYSA-N |
| SMILES | N1C=CC(C=O)=N1 |
| CAS DataBase Reference | 3920-50-1(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22-37/38-41 |
| Safety Statements | 26-36/39 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2933119000 |
2H-Pyrazole-3-carbaldehyde price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS009918 | 1H-Pyrazole-3-carbaldehyde AldrichCPR | 50 mg | $107 | 2025-07-31 | Buy | |
| Sigma-Aldrich | CDS009918 | 1H-Pyrazole-3-carbaldehyde AldrichCPR | 3920-50-1 | 50mg | $104 | 2024-03-01 | Buy |
| TCI Chemical | P2261 | Pyrazole-3-carboxaldehyde >98.0%(GC) | 3920-50-1 | 200mg | $83 | 2026-04-30 | Buy |
| TCI Chemical | P2261 | Pyrazole-3-carboxaldehyde >98.0%(GC) | 3920-50-1 | 1g | $331 | 2026-04-30 | Buy |
| Usbiological | 412422 | 1H-Pyrazole-3-carboxaldehyde | 3920-50-1 | 1g | $333 | 2026-06-03 | Buy |
2H-Pyrazole-3-carbaldehyde Chemical Properties,Uses,Production
Chemical Properties
Colorless Solid
Uses
1H-Pyrazole-3-carboxaldehyde is an intermediate used to prepare fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. It is also a building block to synthesize α-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases.
Synthesis
111573-59-2
3920-50-1
The general procedure for the synthesis of 3-pyrazolecarboxaldehyde from 3-dimethoxymethyl-1H-pyrazole: 2.3 kg of formic acid was added slowly and dropwise to 15.5 kg of an aqueous solution containing 13.8 kg of 3-dimethoxymethyl-1H-pyrazole at 0-15 °C. Subsequently, the reaction mixture was magnetically stirred at 25 °C for 12 h. A light yellow solid was obtained upon completion of the reaction. The precipitate was separated by filtration and the filter cake was washed with 10 L of water to give 643 g of the final yellow solid product 3-pyrazolecarboxaldehyde.
References
[1] Journal of Organic Chemistry, 2007, vol. 72, # 15, p. 5890 - 5893
[2] Chinese Journal of Catalysis, 2016, vol. 37, # 9, p. 1446 - 1450
[3] European Journal of Medicinal Chemistry, 1993, vol. 28, # 2, p. 129 - 140
[4] Patent: CN107235982, 2017, A. Location in patent: Paragraph 0008
2H-Pyrazole-3-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Ailfield Chemical Co., Ltd. | 0311-84468392; 15993358503 | 1013053532@qq.com | China | 254 | 58 |
| Shanghai Zhiyun Biotechnology Co., Ltd | 13119135307 | China | 2766 | 58 | |
| Shanghai Yanchun Biopharmaceutical Technology Co., Ltd | 4001-009266 17349750668 | product@sci-e.com | China | 2808 | 58 |
| Nanjing Jubai Biomedical Technology Co., Ltd. | 13585203734 | info@jbzml.com | China | 200 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Lastest Price from 2H-Pyrazole-3-carbaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-08-15 | 2H-PYRAZOLE-3-CARBALDEHYDE
3920-50-1
|
$1.00 | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2023-07-25 | 2H-PYRAZOLE-3-CARBALDEHYDE
3920-50-1
|
1kg | 99% | 20tons | Jiangsu Magic Biotechnology Co., Ltd | ||
 |
2019-07-06 | 2H-PYRAZOLE-3-CARBALDEHYDE
3920-50-1
|
$7.00 | 1kg | 99% | 100kg | Career Henan Chemical Co |
-
- 2H-PYRAZOLE-3-CARBALDEHYDE
3920-50-1
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2H-PYRAZOLE-3-CARBALDEHYDE
3920-50-1
- 99%
- Jiangsu Magic Biotechnology Co., Ltd
-
- 2H-PYRAZOLE-3-CARBALDEHYDE
3920-50-1
- $7.00
- 99%
- Career Henan Chemical Co
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