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4-(Hexafluoro-2-hydroxyisopropyl)aniline

4-(Hexafluoro-2-hydroxyisopropyl)aniline structure

CAS No.: 722-92-9

Chemical Name:: 4-(Hexafluoro-2-hydroxyisopropyl)aniline

Synonyms: 4-(HexafL;JACS-722-92-9;2-(4-Amino-Phenyl;uoro-2-hydroxyisopropyL;2-(4-Aminophenyl) hexafluoropropan-ol;2-(4-AMINOPHENYL)HEXAFLUORO-2-PROPANOL;4-(Hexafluoro-2-hydroxyisopropyl)aniline;4-(Hexafluoro-2-hydroxyisopropyl)aniline97%;4-(Hexafluoro-2-hydroxyisopropyl)aniline 97%;4-Amino---Bis(Trifluoromethyl)Benzyl Alcohol

CBNumber:: CB4677860

Molecular Formula:: C9H7F6NO

Molecular Weight:: 259.15

MDL Number:: MFCD00039258

MOL File:: 722-92-9.mol

MSDS File:: SDS

Last updated:2026-09-12 18:52:56

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4-(Hexafluoro-2-hydroxyisopropyl)aniline Properties

Melting point	147-152 °C
Boiling point	292.9±40.0 °C(Predicted)
Density	1.505±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
pka	9.86±0.15(Predicted)
form	Crystalline Powder
color	Light brown
BRN	1473737
InChI	InChI=1S/C9H7F6NO/c10-8(11,12)7(17,9(13,14)15)5-1-3-6(16)4-2-5/h1-4,17H,16H2
InChIKey	TZEJXCIGVMTMDY-UHFFFAOYSA-N
SMILES	C(O)(C(F)(F)F)(C(F)(F)F)C1C=CC(N)=CC=1

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Warning

Hazard statements

H301-H315-H319-H335

Precautionary statements

P261-P280a-P301+P310a-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

36/37/38

Safety Statements

37/39-26

RIDADR

2811

Hazard Note

Irritant/Keep Cold under Argon

HazardClass

IRRITANT

HazardClass

6.1

PackingGroup

Ⅲ

HS Code

29221990

Limited Quantities

5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	0
2		0

4-(Hexafluoro-2-hydroxyisopropyl)aniline price More Price(50)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	PC4740	2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol 97%	722-92-9	1g	$21	2026-06-04	Buy
Apolloscientific	PC4740	2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol 97%	722-92-9	5g	$25	2026-06-04	Buy
Apolloscientific	PC4740	2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol 97%	722-92-9	10g	$40	2026-06-04	Buy
Activate Scientific	AS77020	2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol 98%	722-92-9	1g	$22	2026-06-04	Buy
Activate Scientific	AS77020	2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol 98%	722-92-9	5g	$45	2026-06-04	Buy

Product number	Packaging	Price	Buy
PC4740	1g	$21	Buy
PC4740	5g	$25	Buy
PC4740	10g	$40	Buy
AS77020	1g	$22	Buy
AS77020	5g	$45	Buy

4-(Hexafluoro-2-hydroxyisopropyl)aniline Chemical Properties, Uses, Production

Uses

2-(4-aminobenzene)-1,1,1,3,3,3-hexafluoro-2-propanol can be used to prepare bisphenol AF. Bisphenol AF (hexafluorobisphenol A: 2,2-bis-(4-hydroxyphenyl)hexafluoropropane) is mainly used as a vulcanization accelerator for fluororubber.

Chemical Properties

Light brown crystalline powder

Synthesis

62-53-3

684-16-2

4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE

722-92-9

To a xylene solution of aniline (7, 21.47 mmol) and p-toluenesulfonic acid (pTSA, 1.28 mmol) was added hexafluoroacetone trihydrate (8, 64.42 mmol) and the reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, it was cooled to room temperature to allow the product 4-(hexafluoro-2-hydroxyisopropyl)aniline (9) to crystallize and precipitate, which was collected by filtration and used directly in the next step of the reaction.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 6, p. 1638 - 1642
[2] European Journal of Medicinal Chemistry, 2016, vol. 122, p. 744 - 755
[3] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990, vol. 39, # 2.2, p. 323 - 328
[4] Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990, # 2, p. 383 - 389

4-(Hexafluoro-2-hydroxyisopropyl)aniline Preparation Products And Raw materials

Raw materials

Aniline Hexafluoroacetone p-Toluenesulfonic acid monohydrate 1,3-Cyclohexadiene, 5,5-dimethyl-

Preparation Products

SR3335

4-(Hexafluoro-2-hydroxyisopropyl)aniline Suppliers

Global Suppliers ( 135)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Xiannuo Biotechnology Co., Ltd.	021-50718719 13918719472		China	978	58
Yangzhou modier Electronic Materials Co., Ltd	13761402923 19975033992	market@modeltemol.com	China	7840	58
Changzhou Sifluoro Chemical Co.,Ltd	13275212658	sales@neofluoride.com	China	1975	58
Shanghai Jinghui Industrial Co., Ltd.	021-60125035 18019281355	vlchemjh@126.com	China	293	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	+86-21-54098501	sales@sinch.com.cn	China	11592	64

Supplier	Advantage
Shanghai Xiannuo Biotechnology Co., Ltd.	58
Yangzhou modier Electronic Materials Co., Ltd	58
Changzhou Sifluoro Chemical Co.,Ltd	58
Shanghai Jinghui Industrial Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.	64

View Latest Price from 4-(Hexafluoro-2-hydroxyisopropyl)aniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE 722-92-9	$1.00-50.00	1KG	99%		Henan Fengda Chemical Co., Ltd
2025-04-04	4-(Hexafluoro-2-hydroxyisopropyl)aniline 722-92-9		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2022-02-22	4-(Hexafluoro-2-hydroxyisopropyl)aniline 722-92-9		1KG	98.0%	100 tons	Honest Joy Holdings Limited

4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE
722-92-9
$1.00-50.00
99%
Henan Fengda Chemical Co., Ltd

4-(Hexafluoro-2-hydroxyisopropyl)aniline
722-92-9
98%
Henan Aochuang Chemical Co.,Ltd.

4-(Hexafluoro-2-hydroxyisopropyl)aniline
722-92-9
$0.00
98.0%
Honest Joy Holdings Limited

4-(Hexafluoro-2-hydroxyisopropyl)aniline Spectrum

4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE(722-92-9)¹HNMR

722-92-9 (4-(Hexafluoro-2-hydroxyisopropyl)aniline) Related Search:

1,1,1,3,3,3-Hexafluoro-2-propanol 4-(Hexafluoro-2-hydroxyisopropyl)aniline 1,1,1,3,3,3-Hexafluoro-2-propanol T0901317 2-(4-Amino-3-methylphenyl)hexafluoroisopropanol

1,1,1,3,3,3-Hexafluoro-2-(4-(methylamino)phenyl)propan-2-ol 2-(4-(Ethylamino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol 1,1,1,3,3,3-Hexafluoro-2-((4-propylamino)phenyl)propan-2-ol 2-(Hexafluoro-2-hydroxyisopropyl)aniline 2-(4-Amino-3,5-dimethyl-phenyl)-1,1,1,3,3,3-hexafluoro-propan-2-ol

2-(((4-(2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)phenyl)amino)methylene)indane-1,3-dione 2-Phenyl-3-((4-(2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)phenyl)amino)inden-1-one 2-(((4-(2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)phenyl)amino)ethylidene)indane-1,3-dione (((4-(2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)phenyl)amino)methylene)methane-1,1-dicarbonitrile 2-((4-(tert-Butyl)phenyl)sulfonyl)-3-((4-(2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)phenyl)amino)prop-2-enenitrile

Diethyl 2-(((4-(2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)phenyl)amino)methylene)propane-1,3-dioate 2-(N-(4-(2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)phenyl)carbamoyl)cyclopropanecarboxylic acid 2-Chloro-N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylacetamide

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4-AMINO-ALPHA,ALPHA-BIS(TRIFLUOROMETHYL)BENZYL ALCOHOL 2-(4-AMINOPHENYL)HEXAFLUORO-2-PROPANOL 4-amino-à-à-bis(trifluoromethyl)benzyl alcohol 4-(Hexafluoro-2-hydroxyisopropyl)aniline 97% 4-(Hexafluoro-2-hydroxyisopropyl)aniline97% 2-(4-AMINO-PHENYL)-1,1,1,3,3,3-HEXAFLUORO-PROPAN-2-OL 2-(4-Aminophenyl) hexafluoropropan-ol 2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol,97% 2-(4-AMINOPHENYL)-1,1,1,3,3,3-HEXAFLUORO-2-PROPANOL 2-(4-Amino-Phenyl 4-Amino---Bis(Trifluoromethyl)Benzyl Alcohol benzenemethanol, 4-amino-alpha,alpha-bis(trifluoromethyl)- 2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol 97% 4-(1,1,1,3,3,3-Hexafluoro-2-hydroxyprop-2-yl)aniline 2-(4-AMinophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol, 97% 5GR 4-(1,1,1,3,3,3-Hexafluoro-2-hydroxyprop-2-yl)aniline, 4-[Perfluoro(2-hydroxyprop-2-yl)]aniline 2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol97% 4-Amino-A,alpha-Bis(Trifluoromethyl)-Benzenemethanol JACS-722-92-9 4-(HexafL uoro-2-hydroxyisopropyL Benzenemethanol, 4-amino-α,α-bis(trifluoromethyl)- 4-(Hexafluoro-2-hydroxyisopropyl)anilineQ: What is 4-(Hexafluoro-2-hydroxyisopropyl)aniline Q: What is the CAS Number of 4-(Hexafluoro-2-hydroxyisopropyl)aniline Q: What is the storage condition of 4-(Hexafluoro-2-hydroxyisopropyl)aniline 2-(4-Aminophenyl)-1,1,1,333-hexafluoropropane-2-ol 4-(Hexafluoro-2-hydroxyisopropyl)aniline 722-92-9 C8H7F6NO C9H7F6NO