2-Bromo-5-methylthiophene
- CAS No.
- 765-58-2
- Chemical Name:
- 2-Bromo-5-methylthiophene
- Synonyms
- Thiophene, 2-bromo-5-methyl-;2-Bromo-5-methylthio;bromomethylthiophene;2-BROMO-5-METHYLTHIOPHENE;5-Methyl-2-bromothiophene;5-Bromo-2-methylthiophene;2-BROMO-5-METHYLTHIOPHENOL;2-BROMO-5-METHYLTHIOPHENE,96%;2-BroMo-5-Methylthiophene, 95+%;2-Bromo-5-methylthiophene ISO 9001：2015 REACH
- CBNumber:
- CB4684448
- Molecular Formula:
- C5H5BrS
- Molecular Weight:
- 177.06
- MDL Number:
- MFCD00130103
- MOL File:
- 765-58-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 65 °C/15 mmHg (lit.) |
|---|---|
| Density | 1.552 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 173 °F |
| storage temp. | 2-8°C |
| form | Liquid Which May Contain Some Precipitate |
| Specific Gravity | 1.552 |
| color | Yellow |
| InChI | InChI=1S/C5H5BrS/c1-4-2-3-5(6)7-4/h2-3H,1H3 |
| InChIKey | ACDLOOGOFKSUPO-UHFFFAOYSA-N |
| SMILES | C1(Br)SC(C)=CC=1 |
| CAS DataBase Reference | 765-58-2(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227 | |||||||||
| Precautionary statements | P210-P280-P403+P235-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38-22 | |||||||||
| Safety Statements | 23-36/37/39-37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
2-Bromo-5-methylthiophene price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 515485 | 2-Bromo-5-methylthiophene 95% | 765-58-2 | 1g | $36.7 | 2022-05-15 | Buy |
| TCI Chemical | B1540 | 2-Bromo-5-methylthiophene (stabilized with Copper chip + NaHCO3) >98.0%(GC) | 765-58-2 | 5g | $26 | 2026-04-30 | Buy |
| TCI Chemical | B1540 | 2-Bromo-5-methylthiophene (stabilized with Copper chip + NaHCO3) >98.0%(GC) | 765-58-2 | 25g | $104 | 2026-04-30 | Buy |
| Apolloscientific | OR15029 | 2-Bromo-5-methylthiophene 98% | 765-58-2 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR15029 | 2-Bromo-5-methylthiophene 98% | 765-58-2 | 5g | $29 | 2026-06-04 | Buy |
2-Bromo-5-methylthiophene Chemical Properties,Uses,Production
Uses
2-Bromo-5-methylthiophene is a heterocyclic compound that can be used as an intermediate in organic synthesis.
Chemical Properties
Yellow liquid
Synthesis
554-14-3
765-58-2
General procedure for the synthesis of 2-bromo-5-methylthiophene from 2-methylthiophene: A bromine solution was prepared by dissolving 48.0 g of bromine (0.3 mol) in 260 cm3 dioxane. This bromine solution was slowly added dropwise under stirring conditions to a solution of 29.4 g 2-methylthiophene (0.3 mmol) dissolved in 140 cm3 dioxane. The reaction mixture was stirred continuously for 3 hours at room temperature. Subsequently, the reaction system was cooled to 0 °C and saturated aqueous sodium bicarbonate solution was carefully added to neutralize the reaction. The mixture was extracted with ethyl acetate and the organic layer was separated. The organic layer was dried over anhydrous sodium sulfate and evaporated under reduced pressure to remove the solvent. The residue was purified by distillation to give 37.2 g 2-bromo-5-methylthiophene (0.21 mol, 70% yield). Boiling point: 68-70 °C (20 mbar). 1H NMR (400 MHz, CDCl3): δ = 2.42 (s, 3H), 6.51 (d, 1H, J = 3.6 Hz), 6.83 (d, 1H, J = 3.6 Hz) ppm. LC-MS: retention time tR = 1.65 min; MS: m/z = 176, 178 ([M+ 1]+, [M+3]+).
References
[1] Journal of Organic Chemistry, 2014, vol. 79, # 4, p. 1836 - 1841
[2] Synthesis, 2002, # 9, p. 1133 - 1135
[3] Green Chemistry, 2018, vol. 20, # 19, p. 4448 - 4452
[4] Synthesis, 2011, # 2, p. 207 - 209
[5] European Journal of Organic Chemistry, 2018, vol. 2018, # 20, p. 2592 - 2602
2-Bromo-5-methylthiophene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aobolihui | 0917-18691729 18691729963 | 2553382659@qq.com | China | 4726 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 |
View Lastest Price from 2-Bromo-5-methylthiophene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-Bromo-5-methylthiophene
765-58-2
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-13 | 2-Bromo-5-methylthiophene
765-58-2
|
1KS | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2026-02-02 | 2-Bromo-5-methylthiophene
765-58-2
|
$1.00 | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 2-Bromo-5-methylthiophene
765-58-2
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 2-Bromo-5-methylthiophene
765-58-2
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 2-Bromo-5-methylthiophene
765-58-2
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
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