3,5-Difluoropyridine
- CAS No.
- 71902-33-5
- Chemical Name:
- 3,5-Difluoropyridine
- Synonyms
- 3,5-Difluropyridine;3,5-DIFLUOROPYRIDINE;Pyridine, 3,5-difluoro-;3,5-Difluoropyridine>3,5-Difluoropyridine98%;3,5-Difluoropyridine 98%;3,5-Difluoropyridine ISO 9001：2015 REACH
- CBNumber:
- CB4751533
- Molecular Formula:
- C5H3F2N
- Molecular Weight:
- 115.08
- MDL Number:
- MFCD03412222
- MOL File:
- 71902-33-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3,5-Difluoropyridine 97% | 703923 | 5g | $167 |
| 3,5-Difluoropyridine >98.0%(GC) | D4038 | 1g | $21 |
| 3,5-Difluoropyridine >98.0%(GC) | D4038 | 5g | $81 |
| 3,5-Difluoropyridine | D447750 | 100mg | $45 |
| 3,5-Difluoropyridine | FD38497 | 2g | $50 |
| More product size | |||
| Boiling point | 92-93°C |
|---|---|
| Density | 1.256 g/mL at 25 °C |
| refractive index | 1.4437 |
| Flash point | 9°C |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 0.39±0.20(Predicted) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| BRN | 7914363 |
| InChI | InChI=1S/C5H3F2N/c6-4-1-5(7)3-8-2-4/h1-3H |
| InChIKey | WRXAZPPGFLETFR-UHFFFAOYSA-N |
| SMILES | C1=NC=C(F)C=C1F |
| CAS DataBase Reference | 71902-33-5(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H302+H312+H332-H315-H319-H335-H400 | |||||||||
| Precautionary statements | P210-P273-P280-P301+P312-P303+P361+P353-P304+P340+P312 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,F,N,Xn | |||||||||
| Risk Statements | 36/37/38-50-20/21/22-11 | |||||||||
| Safety Statements | 26-36/37/39-61-36/37 | |||||||||
| RIDADR | 1993 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Highly Flammable/Irritant | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 Eye Irrit. 2 Flam. Liq. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3,5-Difluoropyridine price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 703923 | 3,5-Difluoropyridine 97% | 71902-33-5 | 5g | $167 | 2023-06-20 | Buy |
| TCI Chemical | D4038 | 3,5-Difluoropyridine >98.0%(GC) | 71902-33-5 | 1g | $21 | 2025-07-31 | Buy |
| TCI Chemical | D4038 | 3,5-Difluoropyridine >98.0%(GC) | 71902-33-5 | 5g | $81 | 2025-07-31 | Buy |
| TRC | D447750 | 3,5-Difluoropyridine | 71902-33-5 | 100mg | $45 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD38497 | 3,5-Difluoropyridine | 71902-33-5 | 2g | $50 | 2021-12-16 | Buy |
3,5-Difluoropyridine Chemical Properties,Uses,Production
Synthesis
Hydrogenolysis of 2,4,6-tribromo-3,5-difluoropyridine occurred rapidly giving
quantitative conversion to 3,5-difluoropyridine (5), with an isolated yield by distillation
of 63%.
Chemical Properties
Liquid
Preparation
Synthesis of 3,5-Difluoropyridine: A solution of 2,4,6-tribromo-3,5-difluoropyridine (11) (34.0 g, 97 mmol) in DCM (200 cm3) was washed with activated carbon and filtered. A palladium catalyst (3.4 g of a 5% Pd/C commercially available product) and triethylamine (45 cm3, 31.5 g, 312 mmol) were added to the filtrate and the mixture hydrogenated in a Parr apparatus at 4 Bar for 21 h. The mixture was filtered, water (200 cm3) added and extracted into DCM. Distillation of the DCM solution on Fischer-Spaltrohr apparatus gave 3,5-difluoropyridine (7.0 g, 61 mmol, 63%), b.p. 92.5 ·c (Found: C, 52.2; H, 3.0; N, 12.2. C5H3F2N2 requires C, 52.2; H, 3.0; N, 12.2%);
IR spectrum no. 1; mass spectrum no. 1; nrnr spectrum no. 8.
References
[1] Patent: US2006/9643, 2006, A1. Location in patent: Page/Page column 4-5
3,5-Difluoropyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Dongfan Chem. Co., Ltd. | 021-34500607 13391355195 | sales@dfanchem.com | CHINA | 61 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29831 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7099 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
View Lastest Price from 3,5-Difluoropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | 3,5-Difluoropyridine
71902-33-5
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | 3,5-Difluoropyridine
71902-33-5
|
US $3.00 / KG | 1KG | 90%-99.9% | 500kg | Career Henan Chemical Co |
-
- 3,5-Difluoropyridine
71902-33-5
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- 3,5-Difluoropyridine
71902-33-5
- US $3.00 / KG
- 90%-99.9%
- Career Henan Chemical Co
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