ChemicalBook >> CAS DataBase List >>11-beta,17-alpha,21-Trihydroxy-5-beta-pregnane-3,20-dione

11-beta,17-alpha,21-Trihydroxy-5-beta-pregnane-3,20-dione

CAS No.
1482-50-4
Chemical Name:
11-beta,17-alpha,21-Trihydroxy-5-beta-pregnane-3,20-dione
Synonyms
dihydrocortisol;5β-Dihydrocortiso;52-Dihydrocortisol;5B-Dihydrocortisol;5β-Dihydrocortisol;5-BETA-DIHYDROCORTISOL;21-Di[methylenebis(oxy)] 5α5B-pregnane-11B-17A-21-triol-3-20-dione;5β-Pregnane-11β,17α,21-triol-3,20-dione;5β-PREGNAN-11β, 17, 21-TRIOL-3, 20-DIONE
CBNumber:
CB4757474
Molecular Formula:
C21H32O5
Molecular Weight:
364.48
MDL Number:
MFCD00070050
MOL File:
1482-50-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:57

11-beta,17-alpha,21-Trihydroxy-5-beta-pregnane-3,20-dione Properties

Melting point >173°C (dec.)
Boiling point 544.5±50.0 °C(Predicted)
Density 1.249±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 12.50±0.70(Predicted)
color White to Off-White

11-beta,17-alpha,21-Trihydroxy-5-beta-pregnane-3,20-dione price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SMB01348 Dihydrocortisol ≥95% (HPLC) 1482-50-4 25MG $116 2026-04-30 Buy
Sigma-Aldrich SMB01348 Dihydrocortisol ≥95% (HPLC) 1482-50-4 100MG $258 2026-04-30 Buy
ChemScene CS-0146622 5β-Dihydrocortisol 99.86% 1482-50-4 5mg $121 2026-06-04 Buy
ChemScene CS-0146622 5β-Dihydrocortisol 99.86% 1482-50-4 10mg $195 2026-06-04 Buy
ApexBio Technology BA3068 5β-Dihydrocortisol 1482-50-4 5mg $252 2026-05-06 Buy
Product number Packaging Price Buy
SMB01348 25MG $116 Buy
SMB01348 100MG $258 Buy
CS-0146622 5mg $121 Buy
CS-0146622 10mg $195 Buy
BA3068 5mg $252 Buy

11-beta,17-alpha,21-Trihydroxy-5-beta-pregnane-3,20-dione Chemical Properties,Uses,Production

Uses

5β-Dihydrocortisol, is a derivative of Cortisol (H714615), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland.

Definition

ChEBI: 5beta-dihydrocortisol is a 17alpha-hydroxy-C21-steroid that is cortisol in which the 4-5 double bond has undergone formal hydrogenation to give the corresponding 5beta- steroid. It is a 21-hydroxy steroid, a 17alpha-hydroxy-C21-steroid, an 11beta-hydroxy steroid, a 3-oxo-5beta-steroid, a primary alpha-hydroxy ketone, a triol, a secondary alcohol, a diketone, a 20-oxo steroid and a tertiary alpha-hydroxy ketone.

in vivo

5β-Dihydrocortisol (0.1-1.0%; 18 d) potentiates the action of topically applied Dexamethasone (0.06%) in raising the intraocular pressure (IOP) in young rabbits[3].

11-beta,17-alpha,21-Trihydroxy-5-beta-pregnane-3,20-dione Preparation Products And Raw materials

Raw materials

Preparation Products

11-beta,17-alpha,21-Trihydroxy-5-beta-pregnane-3,20-dione Suppliers

Global( 30)Suppliers
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J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
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Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8039 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
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Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 18100677375 sales@szzxbio.com China 1057 58
LGC Science (Shanghai) Ltd. 17717235263 offer.de@lgcgroup.com China 19036 58
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 13120558703 sales@scrbio.com China 9873 58
11,17,21-trihydroxy-,(5beta,11beta)-pregnane-20-dione 11-beta,17,21-trihydroxy-5-beta-pregnane-20-dione 11-beta,17,21-trihydroxy-5-beta-pregnane-3,20-dione 5-BETA-PREGNAN-11-BETA, 17,21-TRIOL-3,20-DIONE 5BETA-PREGNAN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 5-BETA-DIHYDROCORTISOL 5B-pregnane-11B-17A-21-triol-3-20-dione (5R,8S,9S,10S,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one 5B-Dihydrocortisol 5β-Pregnane-11β,17α,21-triol-3,20-dione 52-Dihydrocortisol 21-Di[methylenebis(oxy)] 5&alpha 5β-Dihydrocortisol Pregnane-3,20-dione, 11,17,21-trihydroxy-, (5β,11β)- 5β-PREGNAN-11β, 17, 21-TRIOL-3, 20-DIONE 11β,17α,21-Trihydroxy-5β-Pregnane-3, 20-Dione 5β-Dihydrocortiso dihydrocortisol 11-beta,17-alpha,21-Trihydroxy-5-beta-pregnane-3,20-dione 1482-50-4 Pharmaceuticals, Intermediates & Fine Chemicals, Steroids