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1-Methylpiperidin-4-amine

1-Methylpiperidin-4-amine Structure
1-Methylpiperidin-4-amine structure
CAS No.
41838-46-4
Chemical Name:
1-Methylpiperidin-4-amine
Synonyms
N-Methyl-4-aminopiperidine;1-Methylpiperidine-4-amine;4-Amino-1-methyL;1-Methylpiperidin-4-;1-Methylpiperidin-4-amin;4-Amino-1-methylpiperdine;1-Methylpiperidin-4-amine;1-Methyl-4-piperidinaMine;1-Methyl-4-Amino Piperidine;(1-methyl-4-piperidyl)amine
CBNumber:
CB4758082
Molecular Formula:
C6H14N2
Molecular Weight:
114.19
MDL Number:
MFCD01570549
MOL File:
41838-46-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:17:06
Request For Quotation

1-Methylpiperidin-4-amine Properties

Melting point 203-207
Boiling point 62-64°C 1mm
Density 0.91
refractive index 1.4700-1.4740
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form clear liquid
pka 9.92±0.20(Predicted)
color Colorless to Light orange to Yellow
InChI InChI=1S/C6H14N2/c1-8-4-2-6(7)3-5-8/h6H,2-5,7H2,1H3
InChIKey ALOCUZOKRULSAA-UHFFFAOYSA-N
SMILES N1(C)CCC(N)CC1
CAS DataBase Reference 41838-46-4(CAS DataBase Reference)
UNSPSC Code 12352116

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Corrosion (GHS05)
GHS02,GHS05
Signal word  Danger
Hazard statements  H226-H314
Precautionary statements  P210-P233-P240-P241+P242+P243-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P370+P378-P403+P235-P405-P501
target organs Respiratory system
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22-34-11
Safety Statements  26-36/37/39-45-22-16-9
RIDADR  2920
WGK Germany  WGK 3
HazardClass  IRRITANT
PackingGroup  Ⅱ
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
NFPA 704
2
3 0

1-Methylpiperidin-4-amine price More Price(85)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2046 4-Amino-1-methylpiperidine >98.0%(GC)(T) 41838-46-4 5g $55 2026-04-30 Buy
TCI Chemical A2046 4-Amino-1-methylpiperidine >98.0%(GC)(T) 41838-46-4 25g $158 2026-04-30 Buy
Usbiological 258576 4-Amino-1-methylpiperidine Asreported 41838-46-4 5g $396 2026-06-03 Buy
Usbiological 258576 4-Amino-1-methylpiperidine Asreported 41838-46-4 10g $542 2026-06-03 Buy
Usbiological 258576 4-Amino-1-methylpiperidine Asreported 41838-46-4 25g $835 2026-06-03 Buy
Product number Packaging Price Buy
A2046 5g $55 Buy
A2046 25g $158 Buy
258576 5g $396 Buy
258576 10g $542 Buy
258576 25g $835 Buy

1-Methylpiperidin-4-amine Chemical Properties, Uses, Production

Uses

4-Amino-1-methylpiperidine is used as an organic reagent and pharmaceutical intermediate.

Chemical Properties

Clear colorless to yellow liquid

Synthesis

Benzeneacetamide, 4-chloro-N-[(4-methylphenyl)methyl]-N-4-piperidinyl-

359878-09-4

1-Methylpiperidin-4-amine

41838-46-4

N-((4-methoxyphenyl)methyl)-4-amino-1-methylpiperidine (1 g, 4.27 mmol) was used as starting material, which was dissolved in a methanol solution of 4% formic acid (60 mL). Under argon protection, 10% Pd/C (1 g) was added to the reaction system and the reaction mixture was subsequently heated to reflux for 24 hours. Upon completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was acidified with concentrated hydrochloric acid to a pH of about 1. The resulting solution was concentrated to give a yellow oily substance. The oily substance was purified by fast chromatography (eluent: methanol/dichloromethane = 3:7 with 3.5% ammonia) to give 249 mg (51% yield) of 4-amino-1-methylpiperidine (57-MBT36B) as a white solid. Thin layer chromatography (TLC) Rf value was 0.13 (unfolding agent: 10% dichloromethane solution in methanol with 3.5% ammonia). High performance liquid chromatography-mass spectrometry (HPLC-MS, Method B) showed the molecular ion peak MH+ = 115. ultraviolet/mass spectrometry (UV/MS) detection showed a percent purity of -/100.

References

[1] Patent: WO2007/124136, 2007, A1. Location in patent: Page/Page column 126-127

1-Methylpiperidin-4-amine synthesis

1445-73-4
41838-46-4
Synthesis of 1-Methylpiperidin-4-amine from 1-Methyl-4-piperidone

1-Methylpiperidin-4-amine Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Potassium hydroxide Formaldehyde Formic acid Isonipecotic acid
Bromine Methanol Thionyl chloride 1-Methyl-4-piperidone Benzeneacetamide, 4-chloro-N-[(4-methylphenyl)methyl]-N-4-piperidinyl-

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Preparation Products

TAK-960 1-Methyl-N-(4-nitrophenyl)piperidin-4-amine SURECN6875931 Benzamide, 4-iodo-N-(1-methyl-4-piperidinyl)- 3-methoxy-N-(1-methylpiperidin-4-yl)-4-nitrobenzamide

1-Methylpiperidin-4-amine Suppliers

Global Suppliers ( 287)
Supplier Tel Email Country ProdList Advantage
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 85114309 18982182443 yangli@happysyn.com China 2297 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Wujiang Suke Medical Technology Co., Ltd. +86-512-6320-2019 China 28 60
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Supplier Advantage
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Wujiang Suke Medical Technology Co., Ltd. 60
Beijing Ouhe Technology Co., Ltd 60
JinYan Chemicals(ShangHai) Co.,Ltd. 60

View Latest Price from 1-Methylpiperidin-4-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Methylpiperidin-4-amine pictures 2025-12-24 1-Methylpiperidin-4-amine
41838-46-4
 $49.00 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd
1-Methylpiperidin-4-amine pictures 2024-02-26 1-Methylpiperidin-4-amine
41838-46-4
 1kg 98% BTC Nantong Pharmaceuticals Technology Co.,Ltd
1-Methylpiperidin-4-amine pictures 2021-10-29 1-Methylpiperidin-4-amine
41838-46-4
 $1.00 1000KG 99.99% 10000t Jiangsu Monade Biological Technology Co., Ltd.

1-Methylpiperidin-4-amine Spectrum

1-Methylpiperidin-4-amine(41838-46-4)1HNMR

41838-46-4 (1-Methylpiperidin-4-amine) Related Search:

Methylparaben 1-Aminopiperidine 1-Methyl-4-piperidone Methyl acetate Dibenzylamine
6-Aminocaproic acid Kresoxim-methyl N,N-Dimethyl-1,4-phenylenediamine N-Methylpiperidine 4-Amino-1-benzylpiperidine
Triethanolamine Bensulfuron methyl Thiophanate-methyl 2,2,6,6-Tetramethyl-4-piperidinol Glycine
Aminoethoxyvinyl glycine hydrochloride Metsulfuron methyl Tris(hydroxymethyl)aminomethane

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4-AMINO-1-METHYLPIPERDINE, 98.5% 1-Methylpiperidin-4-amine 1-(5-BROMOPYRIMIDIN-2-YL)[1,4]DIAZEPANE 4-Amino-1-methylpiperdine 1-Methyl-4-Amino Piperidine 4-Amino-1-methyL N-Methyl-4-aminopiperidine 4-Amino-1-methylpiperidine ,97% 4-Amino-1-methylpiperidine ,98% 1-Methylpiperidin-4- 1-methylpiperidin-4-amine(SALTDATA: FREE) 1-Methyl-4-piperidinaMine 1-(5-Bromo-2-pyrimidinyl)-1,4-diazepane (1-methyl-4-piperidyl)amine N-Methyl-4-aMino piperidine,4-aMino-1-Methylpiperdine,1-Methylpiperidin-4-aMine 4-Amino-1-methylpiperidine > 4-Piperidinamine, 1-methyl- 1-Methylpiperidin-4-amine ISO 9001：2015 REACH 4-AMino-1-Methyl piperidine 41838-46-4 1-Methylpiperidin-4-amin 1-Methylpiperidine-4-amine 41838-46-4 C9H13BrN4 API intermediate Pyridine API intermediates