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ChemicalBook >> CAS DataBase List >>6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Structure
6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione structure
CAS No.
6642-31-5
Chemical Name:
6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
Synonyms
6-AMINO-1,3-DIMETHYLPYRIMIDINE-2,4(1H,3H)-DIONE;6-AMINO-1,3-DIMETHYLURACIL;6-AMINO-1,3-DIMETHYLURICIL;AURORA KA-4912;Uradil impurity 42;TIMTEC-BB SBB004028;Aminodimethyluracil;SPECS AB-323/25048015;Dimethyl- 6-aminouracil;Chlorpyrifos Impurity 21
CBNumber:
CB4775315
Molecular Formula:
C6H9N3O2
Molecular Weight:
155.15
MDL Number:
MFCD00006552
MOL File:
6642-31-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:26:36
Request For Quotation

6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Properties

Melting point 295 °C (dec.) (lit.)
Boiling point 243.1±43.0 °C(Predicted)
Density 1.288±0.06 g/cm3(Predicted)
vapor pressure 0Pa at 25℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility 6g/l
form Solid
pka 5.17±0.70(Predicted)
color Pale Beige
PH 6.9 (100g/l, H2O, 20℃)
Water Solubility 7.06g/L(25 ºC)
InChI 1S/C6H9N3O2/c1-8-4(7)3-5(10)9(2)6(8)11/h3H,7H2,1-2H3
InChIKey VFGRNTYELNYSKJ-UHFFFAOYSA-N
SMILES CN1C(N)=CC(=O)N(C)C1=O
LogP -0.4 at 20℃
CAS DataBase Reference 6642-31-5(CAS DataBase Reference)
EPA Substance Registry System 2,4(1H,3H)-Pyrimidinedione, 6-amino-1,3-dimethyl- (6642-31-5)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P501
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  22-26-36/37/39
WGK Germany  1
RTECS  YQ8755000
TSCA  TSCA listed
HS Code  29335990
Storage Class 11 - Combustible Solids
REACH Registrations Active
NFPA 704
1
2 0

6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione price More Price(74)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A52153 6-Amino-1,3-dimethyluracil 98% 6642-31-5 100g $123 2026-04-30 Buy
TCI Chemical A1420 6-Amino-1,3-dimethyluracil >98.0%(HPLC)(T) 6642-31-5 25g $35 2026-04-30 Buy
TCI Chemical A1420 6-Amino-1,3-dimethyluracil >98.0%(HPLC)(T) 6642-31-5 500g $312 2026-04-30 Buy
Usbiological 258360 6-Amino-1,3-dimethyluracil Asreported 6642-31-5 250g $333 2026-06-03 Buy
Usbiological 258360 6-Amino-1,3-dimethyluracil Asreported 6642-31-5 500g $446 2026-06-03 Buy
Product number Packaging Price Buy
A52153 100g $123 Buy
A1420 25g $35 Buy
A1420 500g $312 Buy
258360 250g $333 Buy
258360 500g $446 Buy

6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Chemical Properties, Uses, Production

Chemical Properties

Crystallizes (water). Melting point 295°C (293°C). Decomposes.

Uses

6-Amino-1,3-dimethyluracil is used as a reagent in the synthesis of new pyrimidine and caffeine derivatives that display highly potential antitumor activity. It is also used as a starting material in the synthesis of fused pyrido-pyrimidines.

Synthesis

6-Aminouracil

873-83-6

Iodomethane

74-88-4

6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

6642-31-5

General procedure for the synthesis of 1,3-dimethyl-6-aminouracil from 4-amino-2,6-dihydroxypyrimidine and iodomethane: 4-amino-2,6-dihydroxypyrimidine (1.27 g, 10 mmol) was added to a pre-heated ethanol solution (50 ml) containing KOH (0.56 g, 10 mmol) and heated continuously for 40 min. After completion of the reaction, the mixture was cooled to room temperature followed by addition of iodomethane (20 mmol). The reaction mixture was stirred under heating conditions for 8 hours, after which it was cooled to room temperature. The reaction mixture was poured into cold distilled water (100 ml) to induce precipitation of the final product 1,3-dimethyl-6-aminouracil. The precipitate was collected by filtration and washed with distilled water (100 ml). Finally, recrystallization from methanol gave 1,3-dimethyl-6-aminouracil in yellow crystalline form.

References

[1] Letters in Drug Design and Discovery, 2015, vol. 12, # 6, p. 471 - 478
[2] DRP/DRBP Org.Chem.,
[3] Patent: CN104744471, 2016, B. Location in patent: Paragraph 0026; 0027; 0028

6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione synthesis

873-83-6
74-88-4
6642-31-5
Synthesis of 6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione from 6-Aminouracil and Iodomethane

6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Preparation Products And Raw materials

Raw materials

2-cyano-N-methyl-N-[(methylamino)carbonyl]acetamide Acetic anhydride 1,3-Dimethylurea 6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde Solvent Yellow 93
6-Aminouracil 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one Iodomethane Cyanoacetic acid Ethanol

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Preparation Products

1,3,7-Trimethyluric acid Nifekalant hydrochloride 6-Amino-5-(2-chloro-acetyl)-1,3-dimethyl-1H-pyrimidine-2,4-dione 4,6-Dimethyl-1H-1,2,3-triazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-6-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]-
Methanimidamide, N,N-dimethyl-N'-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-4-pyrimidinyl)- 8-Dimethylaminotheophylline

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6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Suppliers

Global Suppliers ( 447)
Supplier Tel Email Country ProdList Advantage
Shandong Xinhua Pharmceutical Co.,LTD 0533- 2196801 yaojianyong@xhzy.com China 70 60
Shijiazhuang Kunxiangda Technology Co., Ltd. 0311-89683399 15373948595 sales@kunenchem.com China 20 56
Shijiazhuang Kunen Trading Co.,Ltd 0311-89683399 15373948596 sales@kunenchem.com China 42 58
Shijiazhuang Feizi Chemical Technology Co. LTD 0311-85957988 18633001459 sales@feizichem.com China 82 58
ZOUPING MINGYUAN IMP.&EXP. TRADE CO.,LTD. 18364991597 fox793@163.com China 21 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Supplier Advantage
Shandong Xinhua Pharmceutical Co.,LTD 60
Shijiazhuang Kunxiangda Technology Co., Ltd. 56
Shijiazhuang Kunen Trading Co.,Ltd 58
Shijiazhuang Feizi Chemical Technology Co. LTD 58
ZOUPING MINGYUAN IMP.&EXP. TRADE CO.,LTD. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55

View Latest Price from 6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1, 3-Dimethyl-6-Aminouracil pictures 2026-05-28 1, 3-Dimethyl-6-Aminouracil
6642-31-5
 $2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione pictures 2026-03-20 6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
6642-31-5
 $10.00 1KG 99% 5tons Hebei Chuanghai Biotechnology Co., Ltd
6-Amino-1,3-dimethyluracil pictures 2025-08-05 6-Amino-1,3-dimethyluracil
6642-31-5
 1kg 99 20 tons Zouping mingyuan import & export trading co., ltd

6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione Spectrum

6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione(6642-31-5)MS6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione(6642-31-5)1HNMR6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione(6642-31-5)13CNMR6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione(6642-31-5)IR16-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione(6642-31-5)IR26-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione(6642-31-5)Raman

6642-31-5 (6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione) Related Search:

1,3,7-Trimethyluric acid aminometradine 1,3-Dimethyluric acid 6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil 6-Amino-1,3-dimethyl-5-nitrosouracil
Tetramethyluric acid 6-Aminouracil 1,3-Dimethyluracil Semicarbazide 1,3-Dimethylurea
5,6-Diamino-1,3-dimethyluracil hydrate 6-Amino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 6-AMino-1-isobutyl-3-Methyl-5-nitroso-2,4-pyriMidinedione 6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde 1,3-Diethyl-5-nitroso-6-aminouracil
1,3-Diethyl-5,6-diaminouracil 1,3-Diethyl-6-aminouracil 1,3-Dimethyl-6-hydrazinouracil

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AURORA KA-4912 1,3-DIMETHYL-6-AMINOURACIL 1,3-DIMETHYL-4-AMINOURACIL 1,3-DIMETHYL-2,6-DIOXO-4-AMINOTETRAHYDROPYRIMIDINE 4-AMINO-1,3-DIMETHYLURACIL FOR SYNTHESIS 6-AMINO-1,3-DIMETHYLURICIL 6-AMINO-1,3-DIMETHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE 2,4(1H,3H)-Pyrimidinedione, 6-amino-1,3-dimethyl- 4-AMINO-1,3-DIMETHYLURACIL 98+% 6-AMINO-1,3-DIMETHYLURACIL6-AMINO-1,3-DIMETHYL-2,4(1H,3H)-PYRIMIDINEDIONE 3-(4-Nitrophenyl)propionicacidC9H9NO4 6-AMINO-1,3-DIMETHYLURACIL、6-AMINO-1,3-DIMETHYL-2,4(1H,3H)-DIONE Amino-1,3-dimethyluracil,6- 1,3-Dimethyl-6-amino-1,2,3,4-tetrahydropyrimidine-2,4-dione 1,3-Dimethyl-6-amino-2,4(1H,3H)-pyrimidinedione 6-AMINO-1,3-DIMETHYL-1,2,3,4-TETR 4-AMINO-1,3-DIMETHYL-2,6-DIHYDROXYPYRIMIDINE 4-AMINO-1,3-DIMETHYLURACIL TIMTEC-BB SBB004028 SPECS AB-323/25048015 3h)-pyrimidinedione,6-amino-1,3-dimethyl-4(1h 6-amino-1,3-dimethyl-2,4(1h,3h)-pyrimidinedione 6-Amino-1,3-dimethyl-2,4-pyrimidinedione 6-amino-1,3-dimethyl-uraci 6-Imino-1,3-dimethyluracil 6-AMINO-1,3-DIMETHYL-2,4(1H,3H)-DIONE Dimethyl- 6-aminouracil 6-amino-1,3-dimethylpyrimidine-2,4-dione 6-Amino-1,3-dimethyluracil > Chlorpyrifos Impurity 21 6-Amino-1,3-di methyluracil in Acetonitrile Uradil impurity 42 6-Amino-1,3-dimetyl uracil Aminodimethyluracil Amino 1-3 Dimethyl Uracil 6-AMINO-1,3-DIMETHYLURACIL 6-AMINO-1,3-DIMETHYLPYRIMIDINE-2,4(1H,3H)-DIONE 6642-31-5 4316-44-9 Heterocyclic Building Blocks Pyrimidines Building Blocks Amines Building Blocks Heterocyclic Building Blocks Pyrimidines bc0001