Carotene | 7488-99-5

Carotene Properties

Melting point	187.50° (evacuated tube)
alpha	18643 +385° (c = 0.08 in benzene)
Boiling point	644.94°C (rough estimate)
Density	0.9380 (estimate)
refractive index	1.5630 (estimate)
storage temp.	-20°C
solubility	Chloroform (Slightly)
form	Solid
color	Orange to Very Dark Orange
Odor	Slight characteristic
optical activity	〔α〕 643.5 +38518 (c 0.08, C6H6)
λmax	λ: 445-449 nm Amax
BRN	3227603
Stability	Light Sensitive, Temperature Sensitive
InChIKey	ANVAOWXLWRTKGA-MBKINWJBNA-N
SMILES	C(/[C@H]1C(=CCCC1(C)C)C)=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(CCCC1(C)C)C \|&1:1,r\|
EWG's Food Scores	1
FDA UNII	45XWE1Z69V
UNSPSC Code	85151701
NACRES	NA.32

SAFETY

Risk and Safety Statements

Hazard Codes	Xn
Risk Statements	40-67-36/37/38
Safety Statements	36/37-24/25-23
RIDADR	UN 1593 6.1/PG 3
WGK Germany	3
HS Code	32041990
Storage Class	11 - Combustible Solids

Carotene price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	50887	α-Carotene analytical standard	7488-99-5	1mg	$1090	2026-04-30	Buy
Sigma-Aldrich	40395	α-Carotene ≥95.0% (HPLC)	7488-99-5	1mg	$1070	2026-04-30	Buy
Cayman Chemical	19772	α-Carotene ≥95%	7488-99-5	500μg	$70	2026-04-30	Buy
Cayman Chemical	19772	α-Carotene ≥95%	7488-99-5	1mg	$129	2026-04-30	Buy
Cayman Chemical	19772	α-Carotene ≥95%	7488-99-5	5mg	$502	2026-04-30	Buy

Product number	Packaging	Price	Buy
50887	1mg	$1090	Buy
40395	1mg	$1070	Buy
19772	500μg	$70	Buy
19772	1mg	$129	Buy
19772	5mg	$502	Buy

Carotene Chemical Properties, Uses, Production

Description

α-Carotene is a precursor of vitamin A that has been found in various fruits and vegetables. It inhibits proliferation of GOTO human neuroblastoma cells more potently than β-carotene and halts the cell cycle at the G₀/G₁ phase concomitantly with a reduction in the mRNA expression of the protooncogene N-Myc. It is also more potent than β-carotene in mouse models of skin and lung carcinogenesis and decreases the number of hepatomas in mice with spontaneous liver carcinogenesis when administered in drinking water at a concentration of 0.05%. α-Carotene levels are increased in patients with coronary heart disease and are inversely correlated with the risk of estrogen receptor-negative breast cancer.

Uses

carotene is used to provide a red-orange color in cosmetic formulations. It is the primary yellow coloring component of butter, carrots, and egg yolk. Carotene is found in plants as well as in many animal tissues.

Uses

Carotene is a colorant and provitamin, being a hydrocarbon which is one of two subgroups of the carotenoids (yellow, orange, or red pig- ments). the other subgroup is xanthophylls. functions as a colorant with beta-apo-8-carotenal being a red-orange carotenoid and betabeing a yellow carotenoid. it is also a vitamin a precursor that is converted by the body to vitamin a. it is used in ice cream, cheese, and other dairy products.

Uses

(6''R)-β,ε-Carotene is a trans isomer of carotenoid pigment found in plants. It is a terpenoid hydrocarbon.

Definition

ChEBI: (6'R)-beta,epsilon-carotene is an alpha-carotene. It is an enantiomer of a (6'S)-beta,epsilon-carotene.

General Description

α-Carotene is a carotenoid, which shows anticarcinogenic activity.

Biochem/physiol Actions

One of the primary isomers of carotene, enantiomerically pure form of metabolite in carotenoid biosynthesis, biosynthesis of plant secondary metabolites, biosynthesis of terpenoids and steroids and the biosynthesis of secondary metabolites.

Synthesis

A method for the preparation of α-carotene, the method of preparation comprising: a rearrangement reaction of diethyl 3-methyl-5-(2,6,6-trimethyl-2-cyclohexen-1-yl)-1,4-pentadienylphosphonate in an organic solvent under nitrogen protection, in the presence of a base at a temperature of -30-30C; and then to the mixture after the rearrangement reaction of step (I), add Decanedial undergoes a Wittig-Horner condensation reaction at a temperature of 0-30C to obtain α-carotene.

Purification Methods

Purify α-carotene by chromatography on columns of calcium hydroxide, alumina or magnesia. Crystallise it from CS2/MeOH, toluene/MeOH, diethyl ether/pet ether, or acetone/pet ether. Store it in the dark, under N2 or Ar at -20o. It gives a blue colour with max at 542nm when mixed with SbCl3 in CHCl3. [Karrer & Walker Helv Chim Acta 16 641 1933, Eugster et al. Helv Chim Acta 52 1729 1969, Eugster & Karrer Helv Chim Acta 38 610 1955, Strain J Biol Chem 105 523 1934, Beilstein 5 III 2457, 5 IV 2620.]

References

[1] R. WAY A W. Determination of α– and β–Carotene in Fruit and Vegetables by High Performance Liquid Chromatography[J]. Canadian Institute of Food Science and Technology journal, 1982, 16 1: 165-169. DOI: 10.1016/s0315-5463(82)72531-3
[2] M MURAKOSHI. Inhibitory effects of alpha-carotene on proliferation of the human neuroblastoma cell line GOTO.[J]. JNCI Journal of the National Cancer Institute, 1989, 81 21: 1649-1652. DOI: 10.1093/jnci/81.21.1649
[3] M MURAKOSHI. Potent preventive action of alpha-carotene against carcinogenesis: spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by alpha-carotene than by beta-carotene.[J]. Cancer research, 1992, 52 23: 6583-6587.
[4] ANATOL KONTUSH. Lipophilic antioxidants in blood plasma as markers of atherosclerosis: the role of α-carotene and γ-tocopherol[J]. Atherosclerosis, 1999, 144 1: Pages 117-122. DOI: 10.1016/s0021-9150(99)00044-1
[5] ZHANG XUEHONG. Carotenoid intakes and risk of breast cancer defined by estrogen receptor and progesterone receptor status: a pooled analysis of 18 prospective cohort studies123[J]. American Journal of Clinical Nutrition, 2012, 95 3: Pages 713-725. DOI: 10.3945/ajcn.111.014415

Carotene synthesis

Synthesis of Carotene from alpha-Ionone

Carotene Preparation Products And Raw materials

Raw materials

β,β-Carotene, 5,8-epoxy-5,8-dihydro- 15,15'-didehydro-12'-apo-beta,psi-carotenal alpha-Ionone Iodine carrot

PALM OIL

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Preparation Products

Carotene Suppliers

Global Suppliers ( 232)

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing songguan Biotechnology Co., Ltd.	13584088977	2714748392@qq.com	China	609	58
Sinopharm Chemical Reagent Co,Ltd.	86-21-63210123	sj_scrc@sinopharm.com	China	9791	79
XI'AN KPC-CN BIOLOGICAL TECHNOLOGY CO.,LTD.	86-029-85456576	daisy_wang@vip.163.com	China	292	55
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4853	58
TargetMol Chemicals Inc.	021-021-33632979 15002134094	marketing@targetmol.com	China	7993	58
Quality Control Solutions Ltd.	0755-66853366 13670046396	orders@qcsrm.com	China	18188	56
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7717	56
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58
Shanghai Macklin Biochemical Co.,Ltd.	15221275939 15221275939	shenlinxing@macklin.cn	China	15775	55
Shanghai Yongye Biotechnology Co., Ltd.	86-021-61559134 15921386130	3423497944@qq.com	China	8135	55

Supplier	Advantage
Nanjing songguan Biotechnology Co., Ltd.	58
Sinopharm Chemical Reagent Co,Ltd.	79
XI'AN KPC-CN BIOLOGICAL TECHNOLOGY CO.,LTD.	55
MedChemexpress LLC	58
TargetMol Chemicals Inc.	58
Quality Control Solutions Ltd.	56
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
Shanghai Macklin Biochemical Co.,Ltd.	55
Shanghai Yongye Biotechnology Co., Ltd.	55

View Latest Price from Carotene manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-30	α-Carotene 7488-99-5	$999.00			10g	TargetMol Chemicals Inc.
2025-12-24	Carotene 7488-99-5		1KG	99.0%	1000 tons	Shaanxi Dideu Medichem Co. Ltd
2025-04-04	Carotene 7488-99-5		1KG	98%	1ton	Henan Aochuang Chemical Co.,Ltd.

α-Carotene
7488-99-5
$999.00
TargetMol Chemicals Inc.

Carotene
7488-99-5
$0.10
99.0%
Shaanxi Dideu Medichem Co. Ltd

Carotene
7488-99-5
98%
Henan Aochuang Chemical Co.,Ltd.

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