Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>RORγt Inverse agonist 2

RORγt Inverse agonist 2

RORγt Inverse agonist 2 Structure
RORγt Inverse agonist 2 structure
CAS No.
1801197-92-1
Chemical Name:
RORγt Inverse agonist 2
Synonyms
RORγt Inverse agonist 2;Cyclohexanecarboxylic acid, 4-[[(3R)-3-[(4-fluorophenyl)sulfonyl]-3-[4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]-1-pyrrolidinyl]carbonyl]-, trans-
CBNumber:
CB48054526
Molecular Formula:
C27H25F8NO5S
Molecular Weight:
627.54
MDL Number:
MFCD31813912
MOL File:
1801197-92-1.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:21
Request For Quotation

RORγt Inverse agonist 2 Properties

Boiling point 674.6±55.0 °C(Predicted)
Density 1.465±0.06 g/cm3(Predicted)
pka 4.73±0.10(Predicted)

RORγt Inverse agonist 2 Chemical Properties, Uses, Production

Uses

RORγt Inverse agonist 2 is a selective, orally active RORγt inverse agonist with an EC50 of 119 nM[1].

References

[1] Duan JJ, et al. Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists. ACS Med Chem Lett. 2019 Feb 26;10(3):367-373. DOI:10.1021/acsmedchemlett.9b00010

RORγt Inverse agonist 2 Preparation Products And Raw materials

Raw materials

Preparation Products

RORγt Inverse agonist 2 Suppliers

Global Suppliers ( 4)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

1801197-92-1 (RORγt Inverse agonist 2) Related Search:

Cyclohexanecarboxylic acid, 4-[[(3aR,9bR)-9b-[(4-fluorophenyl)sulfonyl]-1,2,3a,4,5,9b-hexahydro-7-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-3H-benz[e]indol-3-yl]carbonyl]-3-methyl-, (3S,4R)- RORγt Inverse agonist 2 Cyclohexanecarboxylic acid, 4-[[(3aR,9bR)-9b-[(4-fluorophenyl)sulfonyl]-1,2,3a,4,5,9b-hexahydro-7-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-3H-benz[e]indol-3-yl]carbonyl]-3-methyl-, (1R,3S,4R)- T0901317 SR3335
ROR gamma-t-IN-1

1of2

RORγt Inverse agonist 2 Cyclohexanecarboxylic acid, 4-[[(3R)-3-[(4-fluorophenyl)sulfonyl]-3-[4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]-1-pyrrolidinyl]carbonyl]-, trans- 1801197-92-1