Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate
- CAS No.
- 4160-61-6
- Chemical Name:
- Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate
- Synonyms
- Methyl 4-oxothiane-3-carboxylate;Methyl 4-oxotetrahydrothiopyran-3-carboxylate;3-Methoxycarbonyl-4-thianone;3-methoxycarbonyltetrahydropyran-4-one;3-Carbomethoxytetrahydro-1,4-thiapyrone;3-(Carbomethoxy)tetrahydrothiopyran-4-one;4-oxotetrahydro-2H-thiopyran-3-carboxylate;ETHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE;methyl 4-oxo-tetrahydro-2H-thiopyran-3-carboxylate;Methyletetrahydro-4-oxo-2H-thiopyran-3-carboxylate
- CBNumber:
- CB4807180
- Molecular Formula:
- C7H10O3S
- Molecular Weight:
- 174.22
- MDL Number:
- MFCD00203485
- MOL File:
- 4160-61-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| Risk Statements | 36/37/38 |
| Safety Statements | 23-26-36/37/39 |
| HS Code | 29349990 |
Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR946543 | Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96% | 4160-61-6 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR946543 | Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96% | 4160-61-6 | 1g | $28 | 2026-06-04 | Buy |
| Apolloscientific | OR946543 | Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96% | 4160-61-6 | 5g | $127 | 2026-06-04 | Buy |
| Apolloscientific | OR946543 | Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96% | 4160-61-6 | 25g | $419 | 2026-06-04 | Buy |
| Apolloscientific | OR946543 | Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96% | 4160-61-6 | 100g | $1590 | 2026-06-04 | Buy |
Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate Chemical Properties, Uses, Production
Uses
Methyl tetrahydro-4-oxo-2H-thiaran-3-carboxylic acid is a carboxylic acid ester derivative that can be used as an organic intermediate.
Chemical Properties
Light pink liquid
Synthesis
4131-74-2
4160-61-6
General procedure for the synthesis of methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate from dimethyl 3,3'-thiodipropionate: 2.7098 g of NaH (60%) was added to a dry 250 ml three-necked flask, followed by the addition of 40 ml of anhydrous tetrahydrofuran (THF) and stirring for 10 min at room temperature. Dimethyl 3,3'-thiodipropionate (10.1015 g) dissolved in THF was added slowly dropwise. After dropwise addition, the reaction mixture was heated to reflux for about 1 hour. The reflux was continued for 1 hour after rinsing the dropping funnel with 10 ml of THF. The reaction was stopped and cooled to room temperature. The pH of the reaction solution was adjusted to 6-7 with 2% hydrochloric acid and then extracted with dichloromethane (30 ml x 3). The organic layers were combined, washed with saturated sodium chloride solution, collected and dried over anhydrous sodium sulfate. After filtration, the solvent was removed under reduced pressure to give 7.5639 g of a yellow oily liquid product in 88.7% yield.
References
[1] Synthesis, 2007, # 10, p. 1584 - 1586
[2] Patent: CN104086562, 2016, B. Location in patent: Paragraph 0136; 0137
[3] Patent: CN105153190, 2017, B. Location in patent: Paragraph 0134; 0165; 0166
[4] Organic Letters, 2018, vol. 20, # 19, p. 6104 - 6107
[5] Journal of the American Chemical Society, 1997, vol. 119, # 18, p. 4285 - 4291
Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| skychemical Co.Ltd | 021-20958197 20965099 | sales@skychemical.com | China | 1182 | 57 |
| Atop-Pharma (Shanghai) Technology Co., Ltd. | +86 (21) 5196-9732 | China | 996 | 57 | |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3537 | 55 |
View Latest Price from Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE
4160-61-6
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-10 | ETHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE
4160-61-6
|
$1.00 | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE
4160-61-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- ETHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE
4160-61-6
- $1.00
- 99%
- Career Henan Chemical Co
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