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METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE

METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE structure

CAS No.: 4160-61-6

Chemical Name:: METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE

Synonyms: Methyl 4-oxothiane-3-carboxylate;Methyl 4-oxotetrahydrothiopyran-3-carboxylate;3-Methoxycarbonyl-4-thianone;3-methoxycarbonyltetrahydropyran-4-one;3-Carbomethoxytetrahydro-1,4-thiapyrone;3-(Carbomethoxy)tetrahydrothiopyran-4-one;4-oxotetrahydro-2H-thiopyran-3-carboxylate;ETHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE;methyl 4-oxo-tetrahydro-2H-thiopyran-3-carboxylate;METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE

CBNumber:: CB4807180

Molecular Formula:: C7H10O3S

Molecular Weight:: 174.22

MDL Number:: MFCD00203485

MOL File:: 4160-61-6.mol

MSDS File:: SDS

Last updated:2026-05-28 02:41:10

Product description	Number	Pack Size	Price
Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96%	OR946543	250mg	$21
Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96%	OR946543	1g	$28
Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96%	OR946543	5g	$127
Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96%	OR946543	25g	$419
Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96%	OR946543	100g	$1590
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METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE Properties

Boiling point	285℃
Density	1.244
Flash point	137℃
storage temp.	Sealed in dry,Room Temperature
pka	10.41±0.20(Predicted)
form	Liquid or Solid
color	Clear colorless to pale yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Risk Statements	36/37/38
Safety Statements	23-26-36/37/39
HS Code	29349990

METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE price More Price(65)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR946543	Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96%	4160-61-6	250mg	$21	2026-06-04	Buy
Apolloscientific	OR946543	Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96%	4160-61-6	1g	$28	2026-06-04	Buy
Apolloscientific	OR946543	Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96%	4160-61-6	5g	$127	2026-06-04	Buy
Apolloscientific	OR946543	Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96%	4160-61-6	25g	$419	2026-06-04	Buy
Apolloscientific	OR946543	Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate 96%	4160-61-6	100g	$1590	2026-06-04	Buy

Product number	Packaging	Price	Buy
OR946543	250mg	$21	Buy
OR946543	1g	$28	Buy
OR946543	5g	$127	Buy
OR946543	25g	$419	Buy
OR946543	100g	$1590	Buy

METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE Chemical Properties,Uses,Production

Uses

Methyl tetrahydro-4-oxo-2H-thiaran-3-carboxylic acid is a carboxylic acid ester derivative that can be used as an organic intermediate.

Chemical Properties

Light pink liquid

Synthesis

4131-74-2

4160-61-6

General procedure for the synthesis of methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate from dimethyl 3,3'-thiodipropionate: 2.7098 g of NaH (60%) was added to a dry 250 ml three-necked flask, followed by the addition of 40 ml of anhydrous tetrahydrofuran (THF) and stirring for 10 min at room temperature. Dimethyl 3,3'-thiodipropionate (10.1015 g) dissolved in THF was added slowly dropwise. After dropwise addition, the reaction mixture was heated to reflux for about 1 hour. The reflux was continued for 1 hour after rinsing the dropping funnel with 10 ml of THF. The reaction was stopped and cooled to room temperature. The pH of the reaction solution was adjusted to 6-7 with 2% hydrochloric acid and then extracted with dichloromethane (30 ml x 3). The organic layers were combined, washed with saturated sodium chloride solution, collected and dried over anhydrous sodium sulfate. After filtration, the solvent was removed under reduced pressure to give 7.5639 g of a yellow oily liquid product in 88.7% yield.

References

[1] Synthesis, 2007, # 10, p. 1584 - 1586
[2] Patent: CN104086562, 2016, B. Location in patent: Paragraph 0136; 0137
[3] Patent: CN105153190, 2017, B. Location in patent: Paragraph 0134; 0165; 0166
[4] Organic Letters, 2018, vol. 20, # 19, p. 6104 - 6107
[5] Journal of the American Chemical Society, 1997, vol. 119, # 18, p. 4285 - 4291

METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE synthesis

Synthesis of METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE from Dimethyl 3,3'-thiodipropanoate

METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Sodium hydride Sodium sulfate Sodium chloride SODIUM HYDROSULFIDE HYDRATE Sodium

Tetrahydrofuran Diethyl ether Ethyl acetate Sodium bicarbonate Acetic acid

Methanol Sodium hydrosulfide Methyl acrylate Dimethyl 3,3'-thiodipropanoate Methyl 3-mercaptopropionate

acrylic acid methyl ester

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Preparation Products

7,8-Dihydro-5H-thiopyrano[4,3-d]pyriMidine-2,4-diol

METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE Suppliers

Global( 81)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Speranza Chemical Co., Ltd.	+86-86-075521030354 +8618688942810	sophieliu@speranzachem.com	China	923	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Wuxi Rejoys chemical Technology Co., Ltd.	0510-86103381	sales@rejoyschem.com	CHINA	976	58
KARMEL TECHNOLOGY (HK) CO.,LIMITED	+8618795957998	karmelhk@126.com	CHINA	2886	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20582	58
Sense Chemicals (Shanghai) Co., Ltd.	+86-21-52751036; +8613818977689	david.dai@sensechemicals.com	China	225	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24597	58
Sichuan Biosynce Pharmatech Co., Ltd.	+8619950309693	diane@biosynce.com	China	4871	58

Supplier	Advantage
Speranza Chemical Co., Ltd.	55
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Wuxi Rejoys chemical Technology Co., Ltd.	58
KARMEL TECHNOLOGY (HK) CO.,LIMITED	58
Dideu Industries Group Limited	58
Sense Chemicals (Shanghai) Co., Ltd.	58
HANGZHOU LEAP CHEM CO., LTD.	58
Sichuan Biosynce Pharmatech Co., Ltd.	58

View Lastest Price from METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE 4160-61-6	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2019-07-10	ETHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE 4160-61-6	$1.00	1KG	99%	1ton	Career Henan Chemical Co

METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE
4160-61-6
$1.10
99.00%
Dideu Industries Group Limited

ETHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE
4160-61-6
$1.00
99%
Career Henan Chemical Co

METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE Spectrum

METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE(4160-61-6)¹HNMR METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE(4160-61-6)¹³CNMR

4160-61-6(METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE)Related Search:

Tetrahydropyran-4-boronic acid pinacol ester 2H-Thiopyran-4-carboxylic acid, tetrahydro-, Methyl ester, 1,1-dioxide 1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid DELTA-TRIDECANOLACTONE Tetrahydro-2H-pyran-4-yl methanesulfonate

2-HYDROXYTETRAHYDROPYRAN Methyl 2-oxotetrahydrofuran-3-carboxylate Tetrahydro-5-oxo-2- furancarboxyli Tetrahydro-2H-thiopyran-4-amine ethyl tetrahydro-2H-pyran-2-carboxylate

METHYL TETRAHYDROPYRAN-3-CARBOXYLATE Thian-4-one S-oxide Tetrahydrothiopyran-4-one oxiMe Tetrahydro-4-oxo-3-furoic acid ethyl ester METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE

Thiane Tetrahydrothiopyran-4-one ETHYL 4-OXO-TETRAHYDRO-3-THIOPYRANCARBOXYLATE

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METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE 4-OXO-TETRAHYDRO-THIOPYRAN-3-CARBOXYLIC ACID METHYL ESTER Methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate ,96% 3-(Carbomethoxy)tetrahydrothiopyran-4-one 3-Carbomethoxytetrahydro-1,4-thiapyrone 3-Methoxycarbonyl-4-thianone methyl 4-oxo-tetrahydro-2H-thiopyran-3-carboxylate 2H-Thiopyran-3-carboxylic acid, tetrahydro-4-oxo-, Methyl ester Methyletetrahydro-4-oxo-2H-thiopyran-3-carboxylate ETHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE METHYL TETRAHYDRO-4-OXO-2H-THIOPYRAN-3-CARBOXYLATE ISO 9001：2015 REACH 4-oxotetrahydro-2H-thiopyran-3-carboxylate 3-methoxycarbonyltetrahydropyran-4-one Methyl 4-oxotetrahydrothiopyran-3-carboxylate Methyl 4-oxothiane-3-carboxylate 4160-61-6 C7H10O3S