6-Bromo-[1,2,4]triazolo[1,5-a]pyridine
- CAS No.
- 356560-80-0
- Chemical Name:
- 6-Bromo-[1,2,4]triazolo[1,5-a]pyridine
- Synonyms
- 6-BroMo[1,2,4]triazolo[1,...;6-Bromo[1,2,4]triazolo[1,5-α]pyridine;6-Bromo-[1,2,4]triazolo[1,5-a]pyridine;[1,2,4]Triazolo[1,5-a]pyridine,6-broMo-;356560-80-0;6-Bromo[1,2,4]triazolo[1,5-a]pyridine 96%;6-Bromo-[1,2,4]triazolo[1,5-a]pyridine;6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE ISO 9001:2015 REACH
- CBNumber:
- CB3837728
- Molecular Formula:
- C6H4BrN3
- Molecular Weight:
- 198.02
- MDL Number:
- MFCD08689534
- MOL File:
- 356560-80-0.mol
- MSDS File:
- SDS
| Melting point | 100-102 |
|---|---|
| Density | 1.89±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Solid |
| pka | 1.46±0.30(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C6H4BrN3/c7-5-1-2-6-8-4-9-10(6)3-5/h1-4H |
| InChIKey | CXRXKDSDRWLKTK-UHFFFAOYSA-N |
| SMILES | C12=NC=NN1C=C(Br)C=C2 |
| UNSPSC Code | 12352200 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Harmful/Irritant/Keep Cold | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
6-Bromo-[1,2,4]triazolo[1,5-a]pyridine price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SYX00141 | 6-Bromo[1,2,4]triazolo[1,5-a]pyridine Aldrich | 356560-80-0 | 1g | $276 | 2026-04-30 | Buy |
| Sigma-Aldrich | 751006 | 6-Bromo-[1,2,4]triazolo[1,5-a]pyridine 97% | 356560-80-0 | 500mg | $89.7 | 2023-06-20 | Buy |
| Usbiological | 263014 | 6-Bromo[1,2,4]triazolo[1,5-a]pyridine Asreported | 356560-80-0 | 500mg | $432 | 2026-06-03 | Buy |
| Usbiological | 263014 | 6-Bromo[1,2,4]triazolo[1,5-a]pyridine Asreported | 356560-80-0 | 1g | $638 | 2026-06-03 | Buy |
| Usbiological | 263014 | 6-Bromo[1,2,4]triazolo[1,5-a]pyridine Asreported | 356560-80-0 | 2g | $970 | 2026-06-03 | Buy |
6-Bromo-[1,2,4]triazolo[1,5-a]pyridine Chemical Properties, Uses, Production
Chemical Properties
Off-white powder
Uses
A selective inhibitor of ALK5 kinase
Synthesis
138888-98-9
356560-80-0
General procedure: N'-(5-bromo-2-pyridinyl)-N,N-dimethylformamidine (4 g, 17.54 mmol, 1.00 eq.) was dissolved in methanol (40 mL) under nitrogen protection and cooled to 0 °C. Subsequently, pyridine (4 mL, 2.00 eq.) and aminoxysulfonic acid (3.6 g, 31.83 mmol, 1.30 eq.) were added sequentially. The reaction mixture was stirred at room temperature for 12 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was diluted with ethyl acetate (150 mL) and washed sequentially with saturated aqueous sodium carbonate solution (50 mL x 1) and water (50 mL x 2). The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent of ethyl acetate/hexane (1:1) to afford 6-bromo-[1,2,4]triazolo[1,5-A]pyridine 2.5 g (72% yield) as a solid. LC/MS (Method D, ESI): retention time = 1.1 min, m/z = 198.0 [M+H]+.
References
[1] Patent: WO2013/127266, 2013, A1. Location in patent: Page/Page column 141
[2] Patent: WO2013/127267, 2013, A1. Location in patent: Page/Page column 92
[3] Patent: WO2013/127268, 2013, A1. Location in patent: Page/Page column 67
[4] Patent: WO2013/130935, 2013, A1. Location in patent: Paragraph 0206
[5] Patent: WO2013/130943, 2013, A1. Location in patent: Paragraph 0214
6-Bromo-[1,2,4]triazolo[1,5-a]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Sino Rare Chemical Co., Ltd. | 512-62857507 | sales@sinorarechem.com | China | 1864 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 13611835272 13611835272 | mmwang@sunwaypharm.com | China | 44090 | 58 |
| Shanghai Kahn Pharmaceutical Co., Ltd. | 021-34979681; 17701870669 | 41513101@qq.com | China | 1788 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shangchem Co., Ltd. | +86-21-68182121 | China | 881 | 52 | |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 28-83379370 13880556291 | tcy@tcypharm.com | China | 509 | 57 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
View Latest Price from 6-Bromo-[1,2,4]triazolo[1,5-a]pyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-08-20 | 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
356560-80-0
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
![]() |
2025-04-04 | 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
356560-80-0
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
![]() |
2019-07-06 | 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
356560-80-0
|
$1.00 | 1KG | 95% | 500KG | Career Henan Chemical Co |
-
![6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE pictures](/ProductImageEN/2021-10/Small/f0a866ab-a045-4328-a43b-bf6118ee045e.jpg)
- 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
356560-80-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
![6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE pictures](/ProductImageEN/2022-09/Small/70de7221-a193-4752-9d65-227195d2e892.png)
- 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
356560-80-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
![6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE pictures](https://img.chemicalbook.com/ProductImageEN/2018-8/Small/f8054f5b-e641-42d8-aa66-401ad7c6f892.png)
- 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
356560-80-0
- $1.00
- 95%
- Career Henan Chemical Co
356560-80-0 (6-Bromo-[1,2,4]triazolo[1,5-a]pyridine) Related Search:
1of4





