Loe 908 hydrochloride
- CAS No.
- 149759-26-2
- Chemical Name:
- Loe 908 hydrochloride
- Synonyms
- LOE 908;Pinokalant;Loe 908 hydrochloride;1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-;3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride
- CBNumber:
- CB4845678
- Molecular Formula:
- C41H48N2O9
- Molecular Weight:
- 712.83
- MDL Number:
- MFCD09038554
- MOL File:
- 149759-26-2.mol
- MSDS File:
- SDS
| Boiling point | 803.7±65.0 °C(Predicted) |
|---|---|
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| form | Solid |
| pka | 5.47±0.20(Predicted) |
| color | Off-white to light yellow |
| FDA UNII | 7J9ZZ971AO |
Loe 908 hydrochloride price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0086177 | Pinokalant 99.09% | 149759-26-2 | 1mg | $303 | 2026-06-04 | Buy |
| ChemScene | CS-0086177 | Pinokalant 99.09% | 149759-26-2 | 5mg | $775 | 2026-06-04 | Buy |
| aablocks | AA00ACKN | Pinokalant | 149759-26-2 | 1mg | $176 | 2026-05-28 | Buy |
| aablocks | AA00ACKN | Pinokalant | 149759-26-2 | 5mg | $364 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD247938 | Pinokalant 98% | 149759-26-2 | 1MG | $230 | 2026-05-27 | Buy |
Loe 908 hydrochloride Chemical Properties, Uses, Production
Uses
LOE 908 Hydrochloride is a isoquinoline derivative and a cation channel blocker. LOE 908 Hydrochloride is a neuroprotective agent.
Biological Activity
Broad spectrum cation channel blocker. Inhibits several cation channels including store-operated calcium channels (SOCs), voltage-operated calcium channels (VOCs), non-selective cation channels (NSCCs), AMPA, NMDA, Na + and K + channels. Neuroprotective; reduces cortical infarct size and improves neurological outcome following middle cerebral artery occlusion.
in vivo
Pinokalant significantly reduces cortical infarct volume from 33.8 mm3 to 24.5 mm3[1].
Loe 908 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Loe 908 hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
View Latest Price from Loe 908 hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Pinokalant
149759-26-2
|
$195.00-636.00 | 98.04% | 10g | TargetMol Chemicals Inc. |
-
- Pinokalant
149759-26-2
- $195.00-636.00
- 98.04%
- TargetMol Chemicals Inc.
