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3-Chloro-4-methylpyridazine

CAS No.
68206-04-2
Chemical Name:
3-Chloro-4-methylpyridazine
Synonyms
3-CHLORO-4-METHYLPYRIDAZINE;3-Chloro-4-methyl-1,2-diazine;Pyridazine, 3-chloro-4-methyl-;3-Chloro-4-methylpyridazine97%;3-Chloro-4-methylpyridazine 97%;3-Chloro-4-methylpyridazine ISO 9001:2015 REACH
CBNumber:
CB4848477
Molecular Formula:
C5H5ClN2
Molecular Weight:
128.56
MDL Number:
MFCD08460979
MOL File:
68206-04-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:57:30

3-Chloro-4-methylpyridazine Properties

Melting point 46-47 °C
Boiling point 254.7±20.0 °C(Predicted)
Density 1.234±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
pka 1.54±0.10(Predicted)
color White

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2933399990

3-Chloro-4-methylpyridazine price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS50392-A 3-Chloro-4-methylpyridazine 97% 68206-04-2 1g $65 2026-06-04 Buy
Activate Scientific AS50392-A 3-Chloro-4-methylpyridazine 97% 68206-04-2 5g $206 2026-06-04 Buy
Apolloscientific OR42178 3-Chloro-4-methylpyridazine 95% 68206-04-2 250mg $112 2026-06-04 Buy
Activate Scientific AS50392-A 3-Chloro-4-methylpyridazine 97% 68206-04-2 25g $874 2026-06-04 Buy
Apolloscientific OR42178 3-Chloro-4-methylpyridazine 95% 68206-04-2 1g $225 2026-06-04 Buy
Product number Packaging Price Buy
AS50392-A 1g $65 Buy
AS50392-A 5g $206 Buy
OR42178 250mg $112 Buy
AS50392-A 25g $874 Buy
OR42178 1g $225 Buy

3-Chloro-4-methylpyridazine Chemical Properties, Uses, Production

Uses

3-Chloro-4-methylpyridazine is a useful intermediate for the synthesis of pesticides and anti-viral drugs.

Synthesis

4-METHYL-3(2H)-PYRIDAZINONE

33471-40-8

3-Chloro-4-methylpyridazine

68206-04-2

General procedure for the synthesis of 3-chloro-4-methylpyridazine from 4-methyl-3(2H)-pyridazinone: The product of step c) (12.2 g, 0.112 mol) was dissolved in phosphorochloridic acid chloride (125 mL) and heated to reflux for 3 hours at 90 °C. Upon completion of the reaction, the reaction mixture was cooled to room temperature and concentrated to near dryness under reduced pressure. The concentrated residue was carefully poured into an ice/water mixture and the pH was adjusted to basic by slowly adding 4N NaOH solution. Subsequently, extraction was carried out with ether and the aqueous phase was then subjected to a secondary extraction with dichloromethane (DCM). All organic phases were combined, washed with water, dried over anhydrous sodium sulfate, filtered and concentrated to dryness under reduced pressure. Finally, the residue was purified by rapid chromatography on silica gel with 2:1 ethyl acetate-isohexane as eluent to give an orange solid product (11.2 g, 78% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 8.97 (1H, d, J = 4.9 Hz), 7.35 (1H, d, J = 4.9 Hz), 2.44 (3H, s) ppm.

References

[1] Patent: WO2004/74290, 2004, A1. Location in patent: Page 79
[2] Pharmaceutical Bulletin, 1957, vol. 5, p. 229,233
[3] Journal of Medicinal Chemistry, 1987, vol. 30, # 2, p. 239 - 249

3-Chloro-4-methylpyridazine Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 130)
Supplier Tel Email Country ProdList Advantage
Xinxiang Anqi Biotechnology Co., Ltd 15036601220 877180706@qq.com China 57 58
Nanbu County Chengxin Technology Co., Ltd. 0838-5675166 15883665058 nbcxkj@126.com China 956 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7881 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9643 60

View Latest Price from 3-Chloro-4-methylpyridazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Chloro-4-methylpyridazine pictures 2026-09-11 3-Chloro-4-methylpyridazine
68206-04-2
1kg 99 Hangzhou Lucky Biology Co., Ltd
3-Chloro-4-methylpyridazine  pictures 2026-08-20 3-Chloro-4-methylpyridazine
68206-04-2
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
3-Chloro-4-methylpyridazine pictures 2022-05-31 3-Chloro-4-methylpyridazine
68206-04-2
98%min 100kgs/month Shanghai Rlavie Technology Co ltd

3-Chloro-4-methylpyridazine Spectrum

3-CHLORO-4-METHYLPYRIDAZINE 3-Chloro-4-methyl-1,2-diazine 3-Chloro-4-methylpyridazine 97% 3-Chloro-4-methylpyridazine97% Pyridazine, 3-chloro-4-methyl- 3-Chloro-4-methylpyridazine ISO 9001:2015 REACH 68206-04-2 Pyridazine series Pyrazines, Pyrimidines & Pyridazines Building Blocks Pyridazine Halides Pyrazines, Pyrimidines & Pyridazines