dimethyl pyridine-3,5-dicarboxylate
- CAS No.
- 4591-55-3
- Chemical Name:
- dimethyl pyridine-3,5-dicarboxylate
- Synonyms
- 5-dicarboxylate;dimethyl pyridine-3;pyridine-3,5-dicarboxyL;Dimethyl 3,5-Pyridinedicarboxylate;dimethyl pyridine-3,5-dicarboxylate;pyridine-3,5-dimacetic acidimethyl ester;3,5-Pyridinedicarboxylic acid dimethyl ester;3,5-Pyridinedicarboxylicacid, 3,5-diMethyl ester;dimethyl pyridine-3,5-dicarboxylate hydrochloride
- CBNumber:
- CB4901677
- Molecular Formula:
- C9H9NO4
- Molecular Weight:
- 195.17
- MDL Number:
- MFCD00518827
- MOL File:
- 4591-55-3.mol
- MSDS File:
- SDS
| Melting point | 84-85 °C |
|---|---|
| Boiling point | 267.6±20.0 °C(Predicted) |
| Density | 1.231±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform, Dichloromethane, Methanol |
| form | Solid |
| pka | 1.16±0.20(Predicted) |
| color | Pale Yellow |
| FDA UNII | 2C5J3Y2XKM |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
| HS Code | 2933399990 |
dimethyl pyridine-3,5-dicarboxylate price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5364 | Dimethyl 3,5-Pyridinedicarboxylate | 4591-55-3 | 5G | $68 | 2026-04-30 | Buy |
| TCI Chemical | D5364 | Dimethyl 3,5-Pyridinedicarboxylate | 4591-55-3 | 25G | $235 | 2026-04-30 | Buy |
| Apolloscientific | OR918879 | Dimethyl pyridine-3,5-dicarboxylate >98% | 4591-55-3 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR918879 | Dimethyl pyridine-3,5-dicarboxylate >98% | 4591-55-3 | 25g | $29 | 2026-06-04 | Buy |
| Apolloscientific | OR918879 | Dimethyl pyridine-3,5-dicarboxylate >98% | 4591-55-3 | 100g | $112 | 2026-06-04 | Buy |
dimethyl pyridine-3,5-dicarboxylate Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Solid
Uses
Dimethyl 3,5-Pyridinedicarboxylate (cas# 4591-55-3) is a compound useful in organic synthesis.
Synthesis
67-56-1
499-81-0
4591-55-3
The general procedure for the synthesis of methyl 3,5-pyridinedicarboxylate from methanol and 3,5-pyridinedicarboxylic acid is as follows: 3,5-pyridinedicarboxylic acid (5.00 g, 29.92 mmol) was dissolved in methanol (100 ml), concentrated sulfuric acid (2 ml) was added slowly as a catalyst, and the reaction mixture was stirred for 18 hrs under reflux conditions. After completion of the reaction, the solvent methanol was removed by distillation under reduced pressure. Subsequently, the reaction mixture was neutralized with aqueous sodium bicarbonate and separated by extraction with dichloromethane. The dichloromethane layer was collected and washed with saturated aqueous sodium chloride solution to remove residual water-soluble impurities. Eventually, the dichloromethane layer was concentrated by decompression to give the white solid product methyl 3,5-pyridinedicarboxylate (5.5 g, 94% yield).
References
[1] ACS Medicinal Chemistry Letters, 2016, vol. 7, # 10, p. 933 - 938
[2] Patent: KR2018/9249, 2018, A. Location in patent: Paragraph 0250; 0251
[3] Angewandte Chemie - International Edition, 2004, vol. 43, # 30, p. 3914 - 3918
[4] Bulletin of the Korean Chemical Society, 2015, vol. 36, # 9, p. 2397 - 2400
[5] Life Sciences, 2005, vol. 78, # 5, p. 495 - 505
dimethyl pyridine-3,5-dicarboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1997 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9336 | 55 |
View Lastest Price from dimethyl pyridine-3,5-dicarboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-08-02 | dimethyl pyridine-3,5-dicarboxylate
4591-55-3
|
$1.00 | 1KG | 95-99% | 500kg/month | Career Henan Chemical Co |
-
- dimethyl pyridine-3,5-dicarboxylate
4591-55-3
- $1.00
- 95-99%
- Career Henan Chemical Co
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