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dimethyl pyridine-3,5-dicarboxylate

CAS No.
4591-55-3
Chemical Name:
dimethyl pyridine-3,5-dicarboxylate
Synonyms
5-dicarboxylate;dimethyl pyridine-3;pyridine-3,5-dicarboxyL;Dimethyl 3,5-Pyridinedicarboxylate;dimethyl pyridine-3,5-dicarboxylate;pyridine-3,5-dimacetic acidimethyl ester;3,5-Pyridinedicarboxylic acid dimethyl ester;3,5-Pyridinedicarboxylicacid, 3,5-diMethyl ester;dimethyl pyridine-3,5-dicarboxylate hydrochloride
CBNumber:
CB4901677
Molecular Formula:
C9H9NO4
Molecular Weight:
195.17
MDL Number:
MFCD00518827
MOL File:
4591-55-3.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:45
Product description Number Pack Size Price
Dimethyl 3,5-Pyridinedicarboxylate D5364 5G $85
Dimethyl 3,5-Pyridinedicarboxylate D5364 25G $294
Dimethyl 3,5-Pyridinedicarboxylate D479055 10g $1055
Dimethylpyridine-3,5-dicarboxylate W6383 100g $1341
Dimethyl pyridine-3,5-dicarboxylate FD139443 25g $393
More product size

dimethyl pyridine-3,5-dicarboxylate Properties

Melting point 84-85 °C
Boiling point 267.6±20.0 °C(Predicted)
Density 1.231±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform, Dichloromethane, Methanol
form Solid
pka 1.16±0.20(Predicted)
color Pale Yellow
FDA UNII 2C5J3Y2XKM

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
HS Code  2933399990

dimethyl pyridine-3,5-dicarboxylate price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D5364 Dimethyl 3,5-Pyridinedicarboxylate 4591-55-3 5G $85 2025-07-31 Buy
TCI Chemical D5364 Dimethyl 3,5-Pyridinedicarboxylate 4591-55-3 25G $294 2025-07-31 Buy
TRC D479055 Dimethyl 3,5-Pyridinedicarboxylate 4591-55-3 10g $1055 2021-12-16 Buy
AK Scientific W6383 Dimethylpyridine-3,5-dicarboxylate 4591-55-3 100g $1341 2021-12-16 Buy
Biosynth Carbosynth FD139443 Dimethyl pyridine-3,5-dicarboxylate 4591-55-3 25g $393 2021-12-16 Buy
Product number Packaging Price Buy
D5364 5G $85 Buy
D5364 25G $294 Buy
D479055 10g $1055 Buy
W6383 100g $1341 Buy
FD139443 25g $393 Buy

dimethyl pyridine-3,5-dicarboxylate Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Uses

Dimethyl 3,5-Pyridinedicarboxylate (cas# 4591-55-3) is a compound useful in organic synthesis.

Synthesis

Methanol

67-56-1

3,5-Pyridinedicarboxylic acid

499-81-0

dimethyl pyridine-3,5-dicarboxylate

4591-55-3

The general procedure for the synthesis of methyl 3,5-pyridinedicarboxylate from methanol and 3,5-pyridinedicarboxylic acid is as follows: 3,5-pyridinedicarboxylic acid (5.00 g, 29.92 mmol) was dissolved in methanol (100 ml), concentrated sulfuric acid (2 ml) was added slowly as a catalyst, and the reaction mixture was stirred for 18 hrs under reflux conditions. After completion of the reaction, the solvent methanol was removed by distillation under reduced pressure. Subsequently, the reaction mixture was neutralized with aqueous sodium bicarbonate and separated by extraction with dichloromethane. The dichloromethane layer was collected and washed with saturated aqueous sodium chloride solution to remove residual water-soluble impurities. Eventually, the dichloromethane layer was concentrated by decompression to give the white solid product methyl 3,5-pyridinedicarboxylate (5.5 g, 94% yield).

References

[1] ACS Medicinal Chemistry Letters, 2016, vol. 7, # 10, p. 933 - 938
[2] Patent: KR2018/9249, 2018, A. Location in patent: Paragraph 0250; 0251
[3] Angewandte Chemie - International Edition, 2004, vol. 43, # 30, p. 3914 - 3918
[4] Bulletin of the Korean Chemical Society, 2015, vol. 36, # 9, p. 2397 - 2400
[5] Life Sciences, 2005, vol. 78, # 5, p. 495 - 505

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View Lastest Price from dimethyl pyridine-3,5-dicarboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
dimethyl pyridine-3,5-dicarboxylate pictures 2019-08-02 dimethyl pyridine-3,5-dicarboxylate
4591-55-3
US $1.00 / KG 1KG 95-99% 500kg/month Career Henan Chemical Co

dimethyl pyridine-3,5-dicarboxylate Spectrum

3,5-Pyridinedicarboxylicacid, 3,5-diMethyl ester dimethyl pyridine-3,5-dicarboxylate 3,5-Pyridinedicarboxylic acid dimethyl ester Dimethyl 3,5-Pyridinedicarboxylate pyridine-3,5-dicarboxyL 5-dicarboxylate dimethyl pyridine-3 dimethyl pyridine-3,5-dicarboxylate hydrochloride pyridine-3,5-dimacetic acidimethyl ester 4591-55-3 Heterocycle-Pyridine series Aromatics Heterocycles