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Thalidomide-O-amido-C8-NH2 hydrochloride

Thalidomide-O-amido-C8-NH2 hydrochloride Structure
Thalidomide-O-amido-C8-NH2 hydrochloride structure
CAS No.
2415263-07-7
Chemical Name:
Thalidomide-O-amido-C8-NH2 hydrochloride
Synonyms
halidomide-O-amido-C8-NH2 hydrochloride;Thalidomide-O-amido-C8-NH2 hydrochloride;Thalidomide 4'-oxyacetamide-alkylC8-amine;N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride;Acetamide, N-(8-aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1)
CBNumber:
CB49023929
Molecular Formula:
C23H31ClN4O6
Molecular Weight:
494.97
MDL Number:
MOL File:
2415263-07-7.mol
TDS File:
TDS
Last updated:2026-04-24 14:59:07
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Thalidomide-O-amido-C8-NH2 hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0120482 Thalidomide-O-amido-C8-NH2 hydrochloride ≥98% 2415263-07-7 5mg $144 2026-06-04 Buy
ChemScene CS-0120482 Thalidomide-O-amido-C8-NH2 hydrochloride ≥98% 2415263-07-7 10mg $231 2026-06-04 Buy
ChemScene CS-0120482 Thalidomide-O-amido-C8-NH2 hydrochloride ≥98% 2415263-07-7 25mg $416 2026-06-04 Buy
aablocks AA01LPWE Thalidomide-O-Amido-C8-Nh2 (Hydrochloride) ≥95%(HPLC) 2415263-07-7 5mg $92 2026-05-30 Buy
aablocks AA01LPWE Thalidomide-O-Amido-C8-Nh2 (Hydrochloride) ≥95%(HPLC) 2415263-07-7 25mg $294 2026-05-30 Buy
Product number Packaging Price Buy
CS-0120482 5mg $144 Buy
CS-0120482 10mg $231 Buy
CS-0120482 25mg $416 Buy
AA01LPWE 5mg $92 Buy
AA01LPWE 25mg $294 Buy

Thalidomide-O-amido-C8-NH2 hydrochloride Chemical Properties,Uses,Production

Uses

Thalidomide-O-amido-C8-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

Biological Activity

Thalidomide-O-amido-C8-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1]. Thalidomide-O-amido-C8-NH2 is a degron-linker (refer to Compound DL7-TL). The PROTAC linker is bound lo at least one targeting ligand. Degron-linker-targeting ligand, wherein the linker is covalently bound lo at least one degron and at least one targeting ligand, the degron is a compound capable of binding to an ubiquitin ligase such as an E3 ubiquitin ligase (e g, cereblon), and the targeting ligand is capable of binding to the targeted protein(s)[1].

IC 50

Cereblon

storage

Desiccate at RT

References

[1]. James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

Thalidomide-O-amido-C8-NH2 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Thalidomide-O-amido-C8-NH2 hydrochloride Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9699 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
SuZhou Medinoah Co.,LTD. 0512-69561983 13914027025 zhang_q@medinoah.com China 3925 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 trendseenbio@gmail.com China 9067 58
Shanghai Haohong Scientific Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39319 58
Abosyn 0512-69561983 13914027025 he_qf@medinoah.com China 3000 58
Shaoyuan Technology (Shanghai) Co., Ltd. 021-50795510 4000665055 marketing@accelachem.com China 9721 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 6206333 13167063860 anhua.mao@aladdin-e.com China 43293 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Chaolan Chemical Technology Center 58
Xi'an Confluore Biological Technology Co., Ltd. 58
SuZhou Medinoah Co.,LTD. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Shanghai Haohong Scientific Co., Ltd. 58
Abosyn 58
Shaoyuan Technology (Shanghai) Co., Ltd. 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58

View Lastest Price from Thalidomide-O-amido-C8-NH2 hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Thalidomide-O-amido-C8-NH2 hydrochloride pictures 2025-06-07 Thalidomide-O-amido-C8-NH2 hydrochloride
2415263-07-7
 100mg >98.00% 100mg Xian confluore Biological Technology Co., Ltd.

2415263-07-7(Thalidomide-O-amido-C8-NH2 hydrochloride)Related Search:

Thalidomide-O-amido-PEG4-azide Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Thalidomide-linker 14 N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)-
Cereblon Ligand 1 E3 Ligase Ligand-Linker Conjugates 21 E3 Ligase Ligand-Linker Conjugates 19 Thalidomide-O-PEG4-Propargyl Thalidomide-linker 10
Acetamide, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl- Thalidomide-O-amido-C4-NH2 hydrochloride Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Thalidomide-O-PEG4-Boc tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate
Thalidomide-linker 13 Thalidomide-linker 15 E3 Ligase Ligand-Linker Conjugates 24 (TFA)

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Thalidomide-O-amido-C8-NH2 hydrochloride N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride Thalidomide 4'-oxyacetamide-alkylC8-amine Acetamide, N-(8-aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1) halidomide-O-amido-C8-NH2 hydrochloride 2415263-07-7