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E3 Ligase Ligand-Linker Conjugates 19

E3 Ligase Ligand-Linker Conjugates 19 structure

CAS No.: 1799711-24-2

Chemical Name:: E3 Ligase Ligand-Linker Conjugates 19

Synonyms: Pomadomide impurity 27;Thalidomide-O-amido-C4-NH2;E3 Ligand-Linker Conjugate 3;Cereblon Ligand-Linker Conjugates 6;E3 Ligase Ligand-Linker Conjugates 19;E3 Ligand-Linker Conjugate 3(E3 Ligase Ligand-Linker Conjugates 19);N-(4-Aminobutyl)-2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]oxy]acetamide;N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide;N-(4-Aminobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide;N-(4-aminobutyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide

CBNumber:: CB83386468

Molecular Formula:: C19H22N4O6

Molecular Weight:: 402.4

MDL Number:: MFCD31630818

MOL File:: 1799711-24-2.mol

MSDS File:: SDS

Last updated:2026-05-28 05:54:39

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E3 Ligase Ligand-Linker Conjugates 19 Properties

Boiling point	757.5±60.0 °C(Predicted)
Density	1.397±0.06 g/cm3(Predicted)
solubility	DMF: insol; DMSO: insol; Ethanol: insol; PBS (pH 7.2): 3 mg/ml
form	A solid
pka	10.68±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

E3 Ligase Ligand-Linker Conjugates 19 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	36666	E3 Ligand-Linker Conjugate 3 ≥95%	1799711-24-2	5mg	$44	2026-04-30	Buy
Cayman Chemical	36666	E3 Ligand-Linker Conjugate 3 ≥95%	1799711-24-2	10mg	$84	2026-04-30	Buy
Cayman Chemical	36666	E3 Ligand-Linker Conjugate 3 ≥95%	1799711-24-2	25mg	$196	2026-04-30	Buy
Cayman Chemical	36666	E3 Ligand-Linker Conjugate 3 ≥95%	1799711-24-2	50mg	$326	2026-04-30	Buy
ChemScene	CS-7889	Thalidomide-O-amido-C4-NH2 ≥98%	1799711-24-2	100mg	$239	2026-06-04	Buy

Product number	Packaging	Price	Buy
36666	5mg	$44	Buy
36666	10mg	$84	Buy
36666	25mg	$196	Buy
36666	50mg	$326	Buy
CS-7889	100mg	$239	Buy

E3 Ligase Ligand-Linker Conjugates 19 Chemical Properties, Uses, Production

Description

Thalidomide-O-acetamido-C4-amine HCl salt is comprised of a Thalidomide based cereblon ligand and a ligand-linker conjugate. This E3 ligase ligand-linker conjugate is used in PROTAC technology.

Uses

Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

IC 50

Cereblon

References

[1] Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression.J Med Chem. 2018 Jan 25;61(2):462-481. DOI:10.1021/acs.jmedchem.6b01816
[2] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

E3 Ligase Ligand-Linker Conjugates 19 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 Ligase Ligand-Linker Conjugates 19 Suppliers

Global Suppliers ( 36)

Supplier	Tel	Email	Country	ProdList	Advantage
BioPharmaMatrix,Inc.	0510-86010668 13395169561;	sales@biopharmamatrix.com	China	5010	55
SuZhou Medinoah Co.,LTD.	0512-69561983 13914027025	zhang_q@medinoah.com	China	3925	58
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1644	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6288	58
Shanghai Minhan Pharmaceutical Technology Co., Ltd.	17612188245	2816925681@qq.com	China	8316	58
Zhejiang Huida Biotech Co., LTD	0571-89903022 18679456698	zilong@hizyme.com	China	8001	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd	043180534350 19917294565	et@chemextension.com	China	4445	58
Molcoo Chemicals Inc.	18627923403	3001039764@qq.com	China	8367	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	59929	58

Supplier	Advantage
BioPharmaMatrix,Inc.	55
SuZhou Medinoah Co.,LTD.	58
Jilin Province Woda Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Shanghai Minhan Pharmaceutical Technology Co., Ltd.	58
Zhejiang Huida Biotech Co., LTD	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd	58
Molcoo Chemicals Inc.	58
Bide Pharmatech Ltd.	58

View Latest Price from E3 Ligase Ligand-Linker Conjugates 19 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	Thalidomide-O-amido-C4-NH2 1799711-24-2				10g	TargetMol Chemicals Inc.

Thalidomide-O-amido-C4-NH2
1799711-24-2
$0.00
TargetMol Chemicals Inc.

1799711-24-2 (E3 Ligase Ligand-Linker Conjugates 19) Related Search:

E3 Ligase Ligand-Linker Conjugates 22 E3 ligase Ligand-Linker Conjugates 11 1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)- Cereblon Ligand 1 E3 Ligase Ligand-Linker Conjugates 21

Thalidomide-O-PEG4-Propargyl Thalidomide-linker 10 Acetamide, 2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl- Thalidomide-O-amido-C4-NH2 hydrochloride Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride

Thalidomide-O-amido-C8-NH2 hydrochloride Thalidomide-O-PEG4-Boc tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate Thalidomide-linker 13 E3 Ligase Ligand-Linker Conjugates 20

E3 Ligase Ligand-Linker Conjugates 1 N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide TFA salt E3 ligase Ligand-Linker Conjugates 17

1of4

E3 Ligase Ligand-Linker Conjugates 19 E3 Ligand-Linker Conjugate 3 Cereblon Ligand-Linker Conjugates 6 Thalidomide-O-amido-C4-NH2 Acetamide, N-(4-aminobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide E3 Ligand-Linker Conjugate 3(E3 Ligase Ligand-Linker Conjugates 19) N-(4-Aminobutyl)-2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]oxy]acetamide N-(4-aminobutyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide Pomadomide impurity 27 N-(4-Aminobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide 1799711-24-2