3-Ethoxy-4-fluorobenzeneboronic acid
- CAS No.
- 900174-65-4
- Chemical Name:
- 3-Ethoxy-4-fluorobenzeneboronic acid
- Synonyms
- 3-Ethoxy-4-fL;5-Borono-2-fluorophenetole;3-Ethoxy-4-fluorophenylboronic acid;3-Ethoxy-4-fluorobenzeneboronic acid;3-Ethoxy-4-fluorobenzeneboronic acidyl;3-Ethoxy-4-fluorobenzeneboronicacid96%;3-Ethoxy-4-fluorobenzeneboronic acid 96%;B-(3-Ethoxy-4-Fluorophenyl)-Boronic Acid;Boronic acid, B-(3-ethoxy-4-fluorophenyl)-;3-Ethoxy-4-fluorophenylboronic Acid (contains varying amounts of Anhydride)
- CBNumber:
- CB4957210
- Molecular Formula:
- C8H10BFO3
- Molecular Weight:
- 183.97
- MDL Number:
- MFCD09475831
- MOL File:
- 900174-65-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P260-P280-P312 | |||||||||
| Hazard Codes | Xi | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2931900090 | |||||||||
| NFPA 704 |
|
3-Ethoxy-4-fluorobenzeneboronic acid price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | E1183 | 3-Ethoxy-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) | 900174-65-4 | 1g | $84 | 2026-04-30 | Buy |
| Activate Scientific | AS49754 | 3-Ethoxy-4-fluorophenylboronic acid 97% | 900174-65-4 | 1g | $44 | 2026-06-04 | Buy |
| Activate Scientific | AS49754 | 3-Ethoxy-4-fluorophenylboronic acid 97% | 900174-65-4 | 5g | $176 | 2026-06-04 | Buy |
| Chem-Impex | 40215 | 3-Ethoxy-4-fluorophenylboronic acid 97-105%(Assaybytitration) | 900174-65-4 | 1G | $122.28 | 2026-05-19 | Buy |
| aablocks | AA00GTAZ | 3-Ethoxy-4-fluorophenylboronic acid ≥97% | 900174-65-4 | 250mg | $10 | 2026-05-28 | Buy |
3-Ethoxy-4-fluorobenzeneboronic acid Chemical Properties, Uses, Production
Uses
suzuki reaction
Synthesis
900174-64-3
900174-65-4
General procedure for the synthesis of 3-ethoxy-4-fluorophenylboronic acid from 2-fluoro-5-bromophenethyl ether: n-butyllithium (n-BuLi, 1.6 M hexane solution, 14.3 mL, 22.8 mmol) was slowly added to a tetrahydrofuran (THF, 60 mL) solution of 2-fluoro-5-bromophenethyl ether (3.86 g, 17.6 mmol) at -78 °C. The reaction mixture was stirred continuously at -78 °C for 40 min, followed by the addition of trimethyl borate (3.63 mL, 33 mmol). The reaction system was slowly warmed from -78 °C to room temperature and stirring was continued for 4 hours. Upon completion of the reaction, the reaction was quenched with 1.0 N hydrochloric acid (40 mL) followed by extraction of the organic phase with ethyl acetate (EtOAc). The organic layer was washed with brine and dried with anhydrous sodium sulfate (Na2SO4). After removal of solvent by evaporation under reduced pressure, the crude product was purified by grinding with ethyl acetate/hexane (1:4) solvent mixture. After filtration, the target product 3-ethoxy-4-fluorophenylboronic acid (9B, 2.2 g, 69% yield) was obtained as a white solid. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 1.42 (t, J = 7.03 Hz, 3H), 4.11 (q, J = 7.03 Hz, 2H), 7.03 (dd, J = 11.42,8.35 Hz, 1H), 7.18-7.29 (m, 2H), 7.35 (d, J = 7.91 Hz, 1H).
References
[1] Patent: US2010/227894, 2010, A1. Location in patent: Page/Page column 29
[2] Patent: US2007/3539, 2007, A1. Location in patent: Page/Page column 69
3-Ethoxy-4-fluorobenzeneboronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
3-Ethoxy-4-fluorobenzeneboronic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
View Latest Price from 3-Ethoxy-4-fluorobenzeneboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 3-Ethoxy-4-fluorobenzeneboronic acid
900174-65-4
|
$1.00 | 1KG | 97%-99% | 1kg; 5kg; 100kg | Career Henan Chemical Co |
-
- 3-Ethoxy-4-fluorobenzeneboronic acid
900174-65-4
- $1.00
- 97%-99%
- Career Henan Chemical Co
900174-65-4 (3-Ethoxy-4-fluorobenzeneboronic acid) Related Search:
1of4
