D-alpha-Amino-epsilon-caprolactam
- CAS No.
- 28957-33-7
- Chemical Name:
- D-alpha-Amino-epsilon-caprolactam
- Synonyms
- D-Lysine lactam;Lysine Impurity;Lysine lactam, D-;Xylose Impurity 6;(R)-3-AMinoazepane;(R)-3-Amino-2-azepanone;(3R)-3-aminoazepan-2-one;(+)-α-Amino-ε-caprolactam;(R)-a-Amino-omega-caprolactam;(R)-3-Amino-Hexahydro-1H-Azepin
- CBNumber:
- CB51074867
- Molecular Formula:
- C6H12N2O
- Molecular Weight:
- 128.17
- MDL Number:
- MFCD00010201
- MOL File:
- 28957-33-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| D-Lysine lactam ≥95% | 31684 | 50mg | $49 |
| D-Lysine lactam ≥95% | 31684 | 100mg | $77 |
| D-Lysine lactam ≥95% | 31684 | 250mg | $178 |
| D-Lysine lactam ≥95% | 31684 | 500mg | $329 |
| (R)-ALPHA-AMINO-OMEGA-CAPROLACTAM 97% | 52018 | 1G | $59 |
| More product size | |||
| Melting point | 97-101 °C |
|---|---|
| Boiling point | 315.1±35.0 °C(Predicted) |
| Density | 1.031±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml |
| form | A neat oil |
| pka | 16.06±0.40(Predicted) |
| InChI | InChI=1S/C6H12N2O/c7-5-3-1-2-4-8-6(5)9/h5H,1-4,7H2,(H,8,9)/t5-/m1/s1 |
| InChIKey | BOWUOGIPSRVRSJ-RXMQYKEDSA-N |
| SMILES | N1CCCC[C@@H](N)C1=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| RIDADR | 1759 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
D-alpha-Amino-epsilon-caprolactam price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 31684 | D-Lysine lactam ≥95% | 28957-33-7 | 50mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 31684 | D-Lysine lactam ≥95% | 28957-33-7 | 100mg | $77 | 2026-04-30 | Buy |
| Cayman Chemical | 31684 | D-Lysine lactam ≥95% | 28957-33-7 | 250mg | $178 | 2026-04-30 | Buy |
| Cayman Chemical | 31684 | D-Lysine lactam ≥95% | 28957-33-7 | 500mg | $329 | 2026-04-30 | Buy |
| AstaTech | 52018 | (R)-ALPHA-AMINO-OMEGA-CAPROLACTAM 97% | 28957-33-7 | 1G | $59 | 2026-04-30 | Buy |
D-alpha-Amino-epsilon-caprolactam Chemical Properties,Uses,Production
Uses
(S)-3-Amino-2-azepanone is a useful research chemical. It is used as an intermediate in the synthesis of bengamide E analogs and capuramycin and its analogs as antibacterial agents. (R)-3-Amino-2-azepanone is used as an intermediate for the synthesis of β-oxocarboxamides as antiviral agents.
Definition
ChEBI: D-2-aminohexano-6-lactam is a 2-aminohexano-6-lactam. It is a conjugate base of a D-2-ammoniohexano-6-lactam. It is an enantiomer of a L-2-aminohexano-6-lactam.
Synthesis
657-27-2
28957-33-7
General procedure for the synthesis of (R)-3-amino-2-caprolactam from L-lysine hydrochloride: 30 g (164 mmol) of L-lysine hydrochloride and 150 mL of 1,2-propanediol as a solvent were added to a 250 mL three-neck flask. Under stirring conditions, 6.57 g of sodium hydroxide was slowly added with continuous stirring until complete dissolution. Subsequently, the reaction mixture was heated to reflux and the reflux reaction was maintained for 5 hours, during which time the water generated was removed by means of a water separator and the progress of the reaction was monitored by thin-layer chromatography (TLC) until the reaction was complete. Upon completion of the reaction, the mixture was cooled to room temperature and the by-product sodium chloride was removed by filtration. The filtrate was acidified dropwise by adding 6 mol/L aqueous hydrochloric acid to the filtrate, followed by a back-extraction operation. The aqueous phase was collected, dried over anhydrous sodium sulfate, and recrystallized by adding appropriate amount of ethanol to finally obtain 21.9 g of white solid product (R)-α-amino caprolactam in 81% yield.
References
[1] Patent: CN106946779, 2017, A. Location in patent: Paragraph 0031; 0033; 0034
D-alpha-Amino-epsilon-caprolactam Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 | sales@anikare.com | China | 9993 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 |
View Lastest Price from D-alpha-Amino-epsilon-caprolactam manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-03 | D-alpha-Amino-epsilon-caprolactam
28957-33-7
|
1KG | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-07-15 | D-Lysine lactam
28957-33-7
|
10g | TargetMol Chemicals Inc. | ||||
 |
2019-09-05 | (3R)-3-aminoazepan-2-one
28957-33-7
|
$1.00 | 1KG | 98% | 1000KG | Career Henan Chemical Co |
-
- D-alpha-Amino-epsilon-caprolactam
28957-33-7
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- D-Lysine lactam
28957-33-7
- $0.00
- TargetMol Chemicals Inc.
-
- (3R)-3-aminoazepan-2-one
28957-33-7
- $1.00
- 98%
- Career Henan Chemical Co
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