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ChemicalBook >> CAS DataBase List >>1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]-

1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]-

1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]- Structure
1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]- structure
CAS No.
2310286-45-2
Chemical Name:
1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]-
Synonyms
IDO1/2-IN-1;1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]-
CBNumber:
CB511131703
Molecular Formula:
C16H18BrFN8O4
Molecular Weight:
485.27
MDL Number:
MOL File:
2310286-45-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Request For Quotation

1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]- Properties

Boiling point 735.0±70.0 °C(Predicted)
Density 1.78±0.1 g/cm3(Predicted)
pka 7.65±0.69(Predicted)
form Solid
color Off-white to light yellow

1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA02AP1G IDO1/2-IN-1 >98% 2310286-45-2 5mg $724 2026-06-02 Buy
aablocks AA02AP1G IDO1/2-IN-1 >98% 2310286-45-2 10mg $1124 2026-06-02 Buy
aablocks AA02AP1G IDO1/2-IN-1 >98% 2310286-45-2 25mg $2202 2026-06-02 Buy
aablocks AA02AP1G IDO1/2-IN-1 >98% 2310286-45-2 50mg $3647 2026-06-02 Buy
Product number Packaging Price Buy
AA02AP1G 5mg $724 Buy
AA02AP1G 10mg $1124 Buy
AA02AP1G 25mg $2202 Buy
AA02AP1G 50mg $3647 Buy

1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]- Chemical Properties, Uses, Production

Uses

IDO1/2-IN-1 (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 exhibits antitumor activies. Orally active[1].

IC 50

IDO1: 28 nM (IC50); IDO2: 144 nM (IC50)

References

[1] He X, et al. Discovery of the First Potent IDO1/IDO2 Dual Inhibitors: A Promising Strategy for Cancer Immunotherapy. J Med Chem. 2021;64(24):17950-17968. DOI:10.1021/acs.jmedchem.1c01305

1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]- Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2934 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Shanghai Tachizaki Biomedical Research Center 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
IDO1/2-IN-1 pictures 2026-07-27 IDO1/2-IN-1
2310286-45-2
 $2140.00-3520.00 10g TargetMol Chemicals Inc.
  • IDO1/2-IN-1 pictures
  • IDO1/2-IN-1
    2310286-45-2
  • $2140.00-3520.00
  • TargetMol Chemicals Inc.

2310286-45-2 (1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]-) Related Search:

1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]-, hydrochloride (1:1) 1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]- BMS-986205 1-Methyl-D-tryptophan Coptisine chloride
Anti-cancer compound library

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1,2,5-Oxadiazole-3-carboximidamide, N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[2-[4-[(2-hydroxyethoxy)methyl]-1H-1,2,3-triazol-1-yl]ethyl]amino]- IDO1/2-IN-1 2310286-45-2 C16H18BrFN8O4