ChemicalBook >> CAS DataBase List >>Adibendan
Adibendan
- CAS No.
- 100510-33-6
- Chemical Name:
- Adibendan
- Synonyms
- BM-14478;Adibendan;Adibendan, 10 mM in DMSO;7,7-Dimethyl-2-(pyridin-4-yl)-3H,5H,6H,7H-imidazo[4,5-F]indol-6-one;5,7-Dihydro-7,7-dimethyl-2-(pyridin-4-yl)pyrrolo[2,3-f]benzimidazol-6(1H)-one;Pyrrolo[2,3-f]benzimidazol-6(3H)-one, 5,7-dihydro-7,7-dimethyl-2-(4-pyridinyl)-
- CBNumber:
- CB51117430
- Molecular Formula:
- C16H14N4O
- Molecular Weight:
- 278.314
- MDL Number:
- MFCD00867123
- MOL File:
- 100510-33-6.mol
- MSDS File:
- SDS
Last updated:2026-09-10 08:17:50
| Melting point | 285-288 °C(Solv: methanol (67-56-1)) |
|---|---|
| Density | 1.302±0.06 g/cm3(Predicted) |
| pka | 9.72±0.40(Predicted) |
| FDA UNII | E87N3L27KX |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Adibendan price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | AEA51033 | 7,7-Dimethyl-2-(pyridin-4-yl)-3H,5H,6H,7H-imidazo[4,5-F]indol-6-one | 100510-33-6 | 50mg | $1930 | 2026-06-04 | Buy |
| Biosynth | AEA51033 | 7,7-Dimethyl-2-(pyridin-4-yl)-3H,5H,6H,7H-imidazo[4,5-F]indol-6-one | 100510-33-6 | 0.5g | $5543.75 | 2026-06-04 | Buy |
| ChemScene | CS-0024848 | Adibendan | 100510-33-6 | 1mg | $231 | 2026-06-04 | Buy |
| ChemScene | CS-0024848 | Adibendan | 100510-33-6 | 5mg | $533 | 2026-06-04 | Buy |
| ChemScene | CS-0024848 | Adibendan | 100510-33-6 | 10mg | $783 | 2026-06-04 | Buy |
Adibendan Chemical Properties, Uses, Production
Uses
Adibendan (BM 14478), a benzimidazole derivative, is an orally active, selective phosphodiesterase III (PDE III) activity inhibitor (IC50=2.0 μM). Adibendan has IC50 values more than 60-fold higher for the inhibition of PDE I or II. Adibendan is a new cardiotonic agent[1].
References
[1] T Bethke, et al. Mechanism of action and cardiotonic activity of a new phosphodiesterase inhibitor, the benzimidazole derivative adibendan (BM 14.478), in guinea-pig hearts. Naunyn Schmiedebergs Arch Pharmacol. 1988 May;337(5):576-82. DOI:10.1007/BF00182735
Adibendan Preparation Products And Raw materials
Raw materials
Preparation Products
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100510-33-6 (Adibendan) Related Search:
Adibendan
5,7-Dihydro-7,7-dimethyl-2-(pyridin-4-yl)pyrrolo[2,3-f]benzimidazol-6(1H)-one
BM-14478
Pyrrolo[2,3-f]benzimidazol-6(3H)-one, 5,7-dihydro-7,7-dimethyl-2-(4-pyridinyl)-
Adibendan, 10 mM in DMSO
7,7-Dimethyl-2-(pyridin-4-yl)-3H,5H,6H,7H-imidazo[4,5-F]indol-6-one
100510-33-6
