Tebufelone
- CAS No.
- 112018-00-5
- Chemical Name:
- Tebufelone
- Synonyms
- NE-11740;Tebufelone;Tebufelone, 10 mM in DMSO;1-(3,5-Ditert-butyl-4-hydroxyphenyl)-5-hexyn-1-one;5-Hexyn-1-one, 1-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-
- CBNumber:
- CB51117793
- Molecular Formula:
- C20H28O2
- Molecular Weight:
- 300.44
- MDL Number:
- MFCD00864365
- MOL File:
- 112018-00-5.mol
- MSDS File:
- SDS
| form | Solid |
|---|---|
| color | White to off-white |
| FDA UNII | O048K9ZFHO |
Tebufelone price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0026641 | Tebufelone 99.52% | 112018-00-5 | 1mg | $70 | 2026-06-04 | Buy |
| aablocks | AA008ZAP | Tebufelone | 112018-00-5 | 1mg | $62 | 2026-05-28 | Buy |
| aablocks | AA008ZAP | Tebufelone | 112018-00-5 | 5mg | $119 | 2026-05-28 | Buy |
| aablocks | AA008ZAP | Tebufelone | 112018-00-5 | 10mg | $166 | 2026-05-28 | Buy |
| aablocks | AA008ZAP | Tebufelone | 112018-00-5 | 25mg | $258 | 2026-05-28 | Buy |
Tebufelone Chemical Properties, Uses, Production
Uses
Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties[1][2].
IC 50
COX-2; 5-LO
References
[1] S M Weisman, et al. Effects of tebufelone (NE-11740), a new anti-inflammatory drug, on arachidonic acid metabolism. Agents Actions. 1994 May;41(3-4):156-63. DOI:10.1007/BF02001910
[2] Sebastian Braun, et al. Carborane-Based Tebufelone Analogs and Their Biological Evaluation In Vitro. ChemMedChem. 2023 Jul 17;18(14):e202300206. DOI:10.1002/cmdc.202300206
Tebufelone Preparation Products And Raw materials
Raw materials
Preparation Products
Tebufelone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | sales@linyuepharm.com | China | 5731 | 55 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Yantai Shengkailun Chemical Technology Co., Ltd. | 13356901049 | mark@sklnchem.cn | China | 9926 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
| Shanghai alkynechem Co., Ltd. | 086-021-15821262312 15821262312 | info@alkynechem.com | China | 2352 | 58 |
| SHANGHAI YOUNG-CHEM CHEMICAL CO., LTD. | 13817489192 | hebe@ychemchemical.com | China | 2435 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49709 | 58 |
