Benzadox
- CAS No.
- 5251-93-4
- Chemical Name:
- Benzadox
- Synonyms
- S 6173;S-7173;Topcide;S-7,173;Topicide;Benzadox;NSC 75601;Benzamidoxyacetic acid;Benzamidooxyacetic acid;o-Benzamidoglycolic acid
- CBNumber:
- CB5115426
- Molecular Formula:
- C9H9NO4
- Molecular Weight:
- 195.17
- MDL Number:
- MFCD00021752
- MOL File:
- 5251-93-4.mol
| Melting point | 140°C |
|---|---|
| Boiling point | 331.83°C (rough estimate) |
| Density | 1.3544 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| solubility | Methanol |
| form | Solid |
| pka | 2.75±0.10(Predicted) |
| color | Pale Yellow |
| Water Solubility | 15.75g/L(temperature not stated) |
| FDA UNII | KSR5R1E31I |
| EPA Substance Registry System | Benzadox (5251-93-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
Benzadox price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S388793 | O-BENZAMIDOGLYCOLIC ACID AldrichCPR | 5251-93-4 | 1 unit | $121 | 2026-04-30 | Buy |
| Sigma-Aldrich | S388793 | O-BENZAMIDOGLYCOLIC ACID AldrichCPR | 5251-93-4 | 1G | $106 | 2023-06-20 | Buy |
| Usbiological | 003232 | (Benzamido)oxy Acetic Acid | 5251-93-4 | 25mg | $531 | 2026-06-03 | Buy |
| TRC | B185100 | (Benzamido)oxyAceticAcid | 5251-93-4 | 250mg | $1320 | 2021-12-16 | Buy |
| Biosynth | FB18178 | (Benzamido)oxy acetic acid | 5251-93-4 | 10mg | $149.9 | 2021-12-16 | Buy |
Benzadox Chemical Properties, Uses, Production
Description
Benzadox is a largely obsolete herbicide that was used to control broadleaved weeds and grasses in sugarbeet crops. Very little data is available regarding its environmental fate, ecotoxicology nor its impact on human health.
Chemical Properties
Pale Yellow Solid
Uses
Hippurate analog. Inhibitor of peptidylglycine α-hydroxylating monooxygenase (PHM). Pesticide.
Production Methods
Benzadox is synthesised through a sequence of acylation and esterification steps typical for amide herbicides. The process begins with benzoyl chloride, which is reacted with hydroxylamine derivatives to form a benzamido intermediate. This intermediate is then coupled with chloroacetic acid or its ester under controlled conditions to introduce the oxyacetic acid moiety, yielding benzadox. The final product is purified by recrystallisation or solvent extraction to achieve high purity suitable for herbicidal use. Production requires strict control of temperature and pH to prevent hydrolysis and ensure stability of the benzamidooxy linkage.
Mechanism of action
Strong inhibitor of alanine aminotransferase
Pesticide Type
Herbicide
Benzadox Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-029-029-81148696 18161915376 | 1027@dideu.com | China | 9989 | 58 |
| Jiaxing Zhejia Biotechnology Co., LTD | 0573-85609002 | zhejia01@163.com | China | 8871 | 58 |
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