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YAP/TAZinhibitor2

YAP/TAZinhibitor2 Structure
YAP/TAZinhibitor2 structure
CAS No.
2762617-31-0
Chemical Name:
YAP/TAZinhibitor2
Synonyms
YAP/TAZinhibitor2;YAP/TAZ inhibitor-2;YAP/TAZ inhibitor-2u00A0;YAP/TAZ inhibitor-2u00A0, 10 mM in DMSO;2-Fluoro-1-(3-(3-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)azetidin-1-yl)prop-2-en-1-one;2-Propen-1-one, 2-fluoro-1-[3-[3-[4-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridin-1-yl]-1-azetidinyl]-
CBNumber:
CB511631551
Molecular Formula:
C19H14F4N4O
Molecular Weight:
390.33
MDL Number:
MOL File:
2762617-31-0.mol
MSDS File:
SDS
Last updated:2026-08-26 13:41:44
Request For Quotation

YAP/TAZinhibitor2 Properties

Boiling point 559.9±50.0 °C(Predicted)
Density 1.45±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (256.19 mM; Need ultrasonic)
pka 2.50±0.30(Predicted)
form Solid
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

YAP/TAZinhibitor2 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0565782 YAP/TAZ inhibitor-2 99.81% 2762617-31-0 5mg $271 2026-06-04 Buy
ChemScene CS-0565782 YAP/TAZ inhibitor-2 99.81% 2762617-31-0 10mg $412 2026-06-04 Buy
ChemScene CS-0565782 YAP/TAZ inhibitor-2 99.81% 2762617-31-0 25mg $704 2026-06-04 Buy
ChemScene CS-0565782 YAP/TAZ inhibitor-2 99.81% 2762617-31-0 50mg $1029 2026-06-04 Buy
ChemScene CS-0565782 YAP/TAZ inhibitor-2 99.81% 2762617-31-0 100mg $1490 2026-06-04 Buy
Product number Packaging Price Buy
CS-0565782 5mg $271 Buy
CS-0565782 10mg $412 Buy
CS-0565782 25mg $704 Buy
CS-0565782 50mg $1029 Buy
CS-0565782 100mg $1490 Buy

YAP/TAZinhibitor2 Chemical Properties, Uses, Production

Uses

YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM. YAP/TAZ inhibitor-2 shows anti-proliferative activity. YAP/TAZ inhibitor-2 shows antitumor activity[1].

Biological Activity

YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM. YAP/TAZ inhibitor-2 shows anti-proliferative activity. YAP/TAZ inhibitor-2 shows antitumor activity[1]. YAP/TAZ inhibitor-2 (compound 5) (0-20000 nM; 24 h) shows antiproliferative activity with an IC50 value of 5.33 nM in NCI-H226 cells[1]. YAP/TAZ inhibitor-2 (0.5, 2, 5, 50 mg/kg; p.o.; daily for 28 days) shows anti-tumor activity with no significant body weight loss during the treatment in BALB/c nude mice (NCI-H226 xenograft model)[1].

in vivo

YAP/TAZ inhibitor-2 (0.5, 2, 5, 50 mg/kg; p.o.; daily for 28 days) shows anti-tumor activity with no significant body weight loss during the treatment in BALB/c nude mice (NCI-H226 xenograft model)[1].

IC 50

YAP/TAZ-TEAD

References

[1]. Xu, xiaofeng, et al. Bicyclic compounds, compositions and use thereof. WO2022037568A1.

YAP/TAZinhibitor2 Preparation Products And Raw materials

Raw materials

Preparation Products

YAP/TAZinhibitor2 Suppliers

Global Suppliers ( 18)
Supplier Tel Email Country ProdList Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4859 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Chuzhou KeMail Chemical Technology Co., Ltd 0550-5196001 15000891977 wj520wjxby@126.com China 1940 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Chengdu PEIP Pharmaceutical Technology Co., LTD. 028-61715638 18011352545 1242335275@qq.com China 473 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58
Supplier Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Chuzhou KeMail Chemical Technology Co., Ltd 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Bide Pharmatech Ltd. 58
Chengdu PEIP Pharmaceutical Technology Co., LTD. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. 58

View Latest Price from YAP/TAZinhibitor2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
YAP/TAZ inhibitor-2 pictures 2026-08-26 YAP/TAZ inhibitor-2
2762617-31-0
 1KG 98 1000 KG Shaanxi Dideu New Materials Co. Ltd
YAP/TAZ inhibitor-2 pictures 2026-07-27 YAP/TAZ inhibitor-2
2762617-31-0
 $84.00-197.00 98.84% 10g TargetMol Chemicals Inc.

YAP/TAZinhibitor2 Spectrum

YAP/TAZinhibitor2(2762617-31-0)1HNMR

2762617-31-0 (YAP/TAZinhibitor2) Related Search:

YAP/TAZinhibitor2 Anti-Aging Compound Library 1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, N-[4-(hydroxymethyl)-3-(phenylmethyl)-2(3H)-thiazolylidene]-, [N(Z)]- Anti-cancer compound library 2-((4,4-dimethylcyclohexyl)sulfonyl)-7-((4-(1-phenylethyl)piperazin-1-yl)sulfonyl)-9H-fluoren-9-one oxime
AICAR

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YAP/TAZ inhibitor-2 YAP/TAZinhibitor2 2-Propen-1-one, 2-fluoro-1-[3-[3-[4-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridin-1-yl]-1-azetidinyl]- YAP/TAZ inhibitor-2u00A0 2-Fluoro-1-(3-(3-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)azetidin-1-yl)prop-2-en-1-one YAP/TAZ inhibitor-2u00A0, 10 mM in DMSO 2762617-31-0