Picrocrocin
- CAS No.
- 138-55-6
- Chemical Name:
- Picrocrocin
- Synonyms
- Picrocroin;Picrocrocin;Picrocroine;Safranbitter;Picrocrocine;Saffron-bitter;Picrocrocin USP/EP/BP;Picrocrocin Safranbitter;Picrocrocin, 10 mM in DMSO;(4S)-2,6,6-trimethyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy
- CBNumber:
- CB51236201
- Molecular Formula:
- C16H26O7
- Molecular Weight:
- 330.37
- MDL Number:
- MFCD09752814
- MOL File:
- 138-55-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 196℃ (ethyl acetate ) |
|---|---|
| alpha | D20 -58° (c = 0.6) |
| Boiling point | 520.4±50.0 °C(Predicted) |
| Density | 1.31±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | 4°C, protect from light |
| solubility |
Acetonitrile: Slightly Soluble Methanol: Soluble Water: Slightly Soluble |
| form | Solid |
| pka | 12.91±0.70(Predicted) |
| color | White to off-white |
| InChI | InChI=1/C16H26O7/c1-8-4-9(5-16(2,3)10(8)6-17)22-15-14(21)13(20)12(19)11(7-18)23-15/h6,9,11-15,18-21H,4-5,7H2,1-3H3/t9-,11-,12-,13+,14-,15-/s3 |
| InChIKey | WMHJCSAICLADIN-LZYGGLMUNA-N |
| SMILES | [C@@H]1(O[C@H]2CC(C)(C)C(C=O)=C(C)C2)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |&1:0,2,14,17,19,21,r| |
| LogP | -0.240 (est) |
| FDA UNII | ON5B022511 |
Picrocrocin price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 39914 | Picrocrocin ≥95% | 138-55-6 | 5mg | $303 | 2026-04-30 | Buy |
| Cayman Chemical | 39914 | Picrocrocin ≥95% | 138-55-6 | 10mg | $545 | 2026-04-30 | Buy |
| Cayman Chemical | 39914 | Picrocrocin ≥95% | 138-55-6 | 50mg | $1513 | 2026-04-30 | Buy |
| Cayman Chemical | 39914 | Picrocrocin ≥95% | 138-55-6 | 100mg | $2723 | 2026-04-30 | Buy |
| Usbiological | 462600 | Picrocrocin | 138-55-6 | 1mg | $523 | 2026-06-03 | Buy |
Picrocrocin Chemical Properties, Uses, Production
Description
Picrocrocin, composing of safranal and glycoside, is one major compounds of saffron (Crocus sativus L. stigma), responsible for the bitter taste of saffron and a molecular marker of this spice, whose taste cannot be imitated from other spices or seasonings, and it can serve to identify true saffron. Saffron possesses various therapeutic activities such as antihypertensive, anticonvulsant, antitussive, antigenototoxic, anticancer, cytotoxic effects, anxiolytic, antioxidant, antidepressant, anti-inflammatory, and relaxant activity. As major bioactive compounds of saffron, picrocrocin also has some valuable medicinal properties similar as saffron, especially anticancer effect.
Antitumor activity
Picrocrocin as component of saffron displays same antitumor activity that have great potential for the prevention and treatment of various cancers through affecting cellular DNA and RNA synthesis and free radical scavenging activities of cancer. The experiments results for studying the effect of picrocrocin on proliferation of human tumoral cells (HeLa cell) in vitro showed that picrocrocin have a dose dependent inhibition of cell growth, and doses of picrocrocin inducing 50% inhibition of HeLa cell growth are 3 mM, in which picrocrocin have minor cytotoxicity for normal cells. Thus, picrocrocin can inhibit the growth of cancer cell. Other study results have showed that picrocrocin with highly bioaccessible could be transported quickly and reduced the proliferation of human adenocarcinoma and hepatocarcinoma cells.
Uses
Picrocrocin is a secondary metabolite of Saffron and has been found to be the taste component of saffron.
Definition
ChEBI: A beta-D-glucoside of beta-cyclocitral; the precursor of safranal. It is the compound most responsible for the bitter taste of saffron.
References
[1] MICHELE SPINELLI. Saffron Characterization by a Multidisciplinary Approach.[J]. Molecules, 2022, 28 1. DOI: 10.3390/molecules28010042
[2] GIANFRANCO DIRETTO. UGT709G1: a novel uridine diphosphate glycosyltransferase involved in the biosynthesis of picrocrocin, the precursor of safranal in saffron (Crocus sativus)[J]. New Phytologist, 2019, 224 2: 725-740. DOI: 10.1111/nph.16079
[3] JULIO ESCRIBANO . Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro[J]. Cancer letters, 1996, 100 1: Pages 23-30. DOI: 10.1016/0304-3835(95)04067-6
Picrocrocin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Ltd. | 82633860 18982077548 | cwb1@biopurify.cn | China | 4630 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Chengdu Herbpurify Co.Ltd. | 2355253622; 18981954830 | 2355253622@qq.com; | China | 1089 | 58 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
Related articles
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- Picrocrocin in saffron offer potential health benefits, including antioxidant, cardioprotective, and neuropsychiatric effects.
- Nov 22,2023
- What is Picrocrocin?
- Picrocrocin, composing of safranal and glycoside, is one major compounds of saffron (Crocus sativus L. stigma), responsible fo....
- Feb 25,2020
- Uses-(4S)-2,6,6-trimethyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-cyclohexene-1-carbaldehyde
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View Latest Price from Picrocrocin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Picrocrocin
138-55-6
|
$72.00-250.00 | 98.40% | 10g | TargetMol Chemicals Inc. | ||
 |
2019-07-06 | picrocrocin
138-55-6
|
$1.00 | 1kg | 95%-99% | 1000kg | Career Henan Chemical Co |
-
- Picrocrocin
138-55-6
- $72.00-250.00
- 98.40%
- TargetMol Chemicals Inc.
-
- picrocrocin
138-55-6
- $1.00
- 95%-99%
- Career Henan Chemical Co
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