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ChemicalBook >> CAS DataBase List >>1H-Benzimidazole-4-carboxylicacid,methylester(9CI)

1H-Benzimidazole-4-carboxylicacid,methylester(9CI)

1H-Benzimidazole-4-carboxylicacid,methylester(9CI) Structure
1H-Benzimidazole-4-carboxylicacid,methylester(9CI) structure
CAS No.
37619-25-3
Chemical Name:
1H-Benzimidazole-4-carboxylicacid,methylester(9CI)
Synonyms
Methyl-1H-benzimidazole-4-carboxylate;Methyl 1H-benzo[d]iMidazole-4-carboxylate;Methyl 4-benzimidazolecarboxylate;Methyl Benzimidazole-4-carboxylate;Methyl 1,3-benzodiazole-4-carboxylate;Methyl 3H-benzimidazole-4-carboxylate;methyl 4(7)-benzimidazolylcarboxylate;methyl 1H-1,3-benzodiazole-4-carboxylate;methyl 1H-benzo[d]imidazole-7-carboxylate;1H-benzo [D] imidazole-4-methyl carboxylate
CBNumber:
CB51290863
Molecular Formula:
C9H8N2O2
Molecular Weight:
176.17
MDL Number:
MFCD09910212
MOL File:
37619-25-3.mol
MSDS File:
SDS
Last updated:2026-05-28 01:56:35
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1H-Benzimidazole-4-carboxylicacid,methylester(9CI) Properties

Boiling point 416.2±18.0 °C(Predicted)
Density 1.324±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 10.78±0.30(Predicted)
Appearance Light brown to black Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
HS Code  2933998090

1H-Benzimidazole-4-carboxylicacid,methylester(9CI) price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR908067 Methyl 1,3-benzodiazole-4-carboxylate 98% 37619-25-3 100mg $21 2026-06-04 Buy
Apolloscientific OR908067 Methyl 1,3-benzodiazole-4-carboxylate 98% 37619-25-3 250mg $24 2026-06-04 Buy
Apolloscientific OR908067 Methyl 1,3-benzodiazole-4-carboxylate 98% 37619-25-3 1g $63 2026-06-04 Buy
Apolloscientific OR908067 Methyl 1,3-benzodiazole-4-carboxylate 98% 37619-25-3 5g $217 2026-06-04 Buy
Apolloscientific OR908067 Methyl 1,3-benzodiazole-4-carboxylate 98% 37619-25-3 25g $1035 2026-06-04 Buy
Product number Packaging Price Buy
OR908067 100mg $21 Buy
OR908067 250mg $24 Buy
OR908067 1g $63 Buy
OR908067 5g $217 Buy
OR908067 25g $1035 Buy

1H-Benzimidazole-4-carboxylicacid,methylester(9CI) Chemical Properties, Uses, Production

Synthesis

Methanol

67-56-1

1H-Benzimidazole-4-carboxylic acid

46006-36-4

1H-Benzimidazole-4-carboxylicacid,methylester(9CI)

37619-25-3

General procedure for the synthesis of methyl 1H-benzo[d]imidazole-4-carboxylate from methanol and benzimidazole-7-carboxylic acid: benzimidazole-7-carboxylic acid (1.136 g, 7.02 mmol) was dissolved in methanol (115 mL) and concentrated HCl and H2SO4 (0.86 mL, 15.45 mmol) were added. The reaction mixture was heated under reflux conditions until thin layer chromatography (TLC) showed that the reaction was complete (24-36 hours). Upon completion of the reaction, the mixture was concentrated to a few mL and the pH was adjusted to 8.5 with 1 M K3PO4 solution. the resulting precipitate was separated by filtration and dried under reduced pressure to afford methyl 1H-benzo[d]imidazole-4-carboxylate (0.940 g, 76% yield) as a white solid. The melting point was 211-213 °C (literature value 204 °C).1H NMR (300 MHz, DMSO-d6) δ 8.31 (s, 1H), 7.95 (dd, J = 8.0,0.9 Hz, 1H), 7.83 (dd, J = 7.6,0.9 Hz, 1H), 7.29 (dd, J = 8.0,7.6 Hz, 1H).13C NMR (75 MHz, DMSO-d6) δ 265.5,144.1,143.6,132.3,124.7,124.3,121.0,113.8.

References

[1] Australian Journal of Chemistry, 1993, vol. 46, # 8, p. 1177 - 1191
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 14, p. 3933 - 3937
[3] Patent: WO2016/138335, 2016, A1. Location in patent: Paragraph 00366

1H-Benzimidazole-4-carboxylicacid,methylester(9CI) Preparation Products And Raw materials

Raw materials

Methanol Formic acid Methyl 2-amino-3-nitrobenzoate 1H-Benzimidazole-4-carboxylic acid

Preparation Products

Methyl 6-nitro-1H-benzo[d]imidazole-4-carboxylate

1H-Benzimidazole-4-carboxylicacid,methylester(9CI) Suppliers

Global Suppliers ( 89)
Supplier Tel Email Country ProdList Advantage
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Acorn PharmaTech Co., Ltd. 025-58395930 sales@acornpharma.com China 982 60
Shanghai Litong Chemical Technology Co.,Ltd. 13598610367 0373-7129549 2468833170@qq.com China 932 58
Shanghai potentpharm CO.,Ltd 13524892556 sales-cn@potentpharm.com China 1011 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. +86-28-85122536 85324413 market@astatech.cn China 8016 55
Shanghai Hekang Biotechnology Co., Ltd. 17721021104 18939837085 2880152141@qq.com China 1840 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Nantong MYBio-pharm. Co., Ltd. 0513-85921823 18662920231 sales@ntminyanmedical.com China 4560 58
Supplier Advantage
Adamas Reagent, Ltd. 59
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Acorn PharmaTech Co., Ltd. 60
Shanghai Litong Chemical Technology Co.,Ltd. 58
Shanghai potentpharm CO.,Ltd 55
9ding chemical ( Shanghai) Limited 56
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. 55
Shanghai Hekang Biotechnology Co., Ltd. 55
Bide Pharmatech Ltd. 60
Nantong MYBio-pharm. Co., Ltd. 58

View Latest Price from 1H-Benzimidazole-4-carboxylicacid,methylester(9CI) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 1H-benzo[d]imidazole-4-carboxylate pictures 2020-01-10 Methyl 1H-benzo[d]imidazole-4-carboxylate
37619-25-3
 $1.00 1KG 99% 200kg Career Henan Chemical Co

1H-Benzimidazole-4-carboxylicacid,methylester(9CI) Spectrum

1H-Benzimidazole-4-carboxylicacid,methylester(9CI)(37619-25-3)1HNMR

37619-25-3 (1H-Benzimidazole-4-carboxylicacid,methylester(9CI)) Related Search:

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Methyl Benzimidazole-4-carboxylate methyl 1H-1,3-benzodiazole-4-carboxylate 1H-Benzimidazole-4-carboxylicacid,methylester(9CI) 1H-Benzimidazole-4-carboxylic acid methyl ester methyl 1H-benzo[d]imidazole-7-carboxylate Methyl 3H-benzimidazole-4-carboxylate Methyl 4-benzimidazolecarboxylate methyl 4(7)-benzimidazolylcarboxylate Methyl 1H-benzo[d]iMidazole-4-carboxylate Methyl 1,3-benzodiazole-4-carboxylate 1H-Benzimidazole-7-carboxylic acid, methyl ester 1H-benzo [D] imidazole-4-methyl carboxylate Methyl-1H-benzimidazole-4-carboxylate 37619-25-3 pharmacetical BENZIMIDAZOLE