FLUQUINCONAZOLE
- CAS No.
- 136426-54-5
- Chemical Name:
- FLUQUINCONAZOLE
- Synonyms
- VISTA;Jockey;Palisade;SN 597265;CASTELLAN;Palisade PM;Jockey 201 FS;Fluquinconazol;FLUQUINCONAZOLE;Jockey (pesticide)
- CBNumber:
- CB5130876
- Molecular Formula:
- C16H8Cl2FN5O
- Molecular Weight:
- 376.17
- MDL Number:
- MFCD01632338
- MOL File:
- 136426-54-5.mol
- MSDS File:
- SDS
| Melting point | 192℃ |
|---|---|
| Boiling point | 623.0±65.0 °C(Predicted) |
| Density | 1.63±0.1 g/cm3(Predicted) |
| vapor pressure | 6.4 x l0-9 Pa (20 °C) |
| storage temp. | 0-6°C |
| Water Solubility | 1 mg l-1(20 °C, pH 6.6) |
| pka | 0.91±0.12(Predicted) |
| Henry's Law Constant | 5.6×108 mol/(m3Pa) at 25℃, Hilal et al. (2008) |
| Major Application |
agriculture environmental |
| InChI | 1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H |
| InChIKey | IJJVMEJXYNJXOJ-UHFFFAOYSA-N |
| SMILES | Fc1ccc2N=C(N(C(=O)c2c1)c3ccc(Cl)cc3Cl)n4cncn4 |
| LogP | 3.240 |
| EWG's Food Scores | 1-2 |
| FDA UNII | 0AE2N0JNI1 |
| EPA Substance Registry System | 4(3H)-Quinazolinone, 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)- (136426-54-5) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301+H331-H312-H315-H372-H410 |
| Precautionary statements | P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P314 |
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T,N |
| Risk Statements | 21-23/25-38-48/25-50/53 |
| Safety Statements | 36/37/39-38-45-60-61 |
| RIDADR | 2588 |
| WGK Germany | 3 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Inhalation Acute Tox. 3 Oral Acute Tox. 4 Dermal Aquatic Acute 1 Aquatic Chronic 1 Skin Irrit. 2 STOT RE 1 Oral |
| Toxicity | LD50 in male, female mice, male, female rats (mg/kg): 325, 180, 112, 112 orally; in male, female rats (mg/kg): 2679, 625 dermally (Russell) |
| REACH Registrations | Inactive |
FLUQUINCONAZOLE price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 46301 | Fluquinconazole PESTANAL | 136426-54-5 | 100mg | $219 | 2026-04-30 | Buy |
| Biosynth | LFA42654 | Fluquinconazole | 136426-54-5 | 50mg | $802.5 | 2026-06-04 | Buy |
| Biosynth | LFA42654 | Fluquinconazole | 136426-54-5 | 0.5g | $2554.7 | 2026-06-04 | Buy |
| TRC | F632053 | Fluquinconazole | 136426-54-5 | 25mg | $340 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | AGR0000185 | FLUQUINCONAZOLE 98.00% | 136426-54-5 | 0.5G | $1001 | 2021-12-16 | Buy |
FLUQUINCONAZOLE Chemical Properties, Uses, Production
Description
Fluquinconazole is a selective protectant and curative fungicide used to control various endophytic diseases mainly on cereals. It has a low aqueous solubility and a low volatility. It can be persistent in both soil and water systems depending on local conditions. Oral toxicity to mammals is classified as moderate but data for chronic health is missing. Toxicity to birds is high and tends to be moderate to most otherr species but slightly less so to bees.
Chemical Properties
Fluoroquinazole pure product is white crystalline solid with a slight odor. Melting point 191.9～193℃. Vapor pressure 6.4×10-9Pa(20℃). Distribution coefficient KowlgP=3.24(pH 5.6,20℃).Henry constant 2.09×10-6Pa -m3/mol(20℃). Relative density 1.58(20℃). Solubility (20℃,g/L): water 0.0015(pH 6.6), acetone 38~50, xylene 9.88, ethanol 3.48, DMSO150~200, dichloromethane 120~150.Stability: in water DT50(25℃ ,pH 7) 21.8d.Stable in aqueous medium to light. Surface tension 70.91mN/m(20℃).
Uses
Agricultural fungicide primarily for cereal crops.
Uses
Fluqinconazole is used to control a wide range of Ascomycetes, Deuteromycetes and Basidiomycetes, by foliar application, on broadleaved and cereal crops.
Definition
ChEBI: Fluquinconazole is a member of the class of quinazolines that is 6-fluoroquinazolin-4-one carrying additional 1,2,4-triazol-1-yl and 2,4-dichlorophenyl substituents at positions 2 and 3 respectively. A fungicide used to control Ascomycetes, Deuteromycetes and Basidiomycetes spp. on cereals, beets and fruit. It has a role as an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor and an antifungal agrochemical. It is a member of quinazolines, a dichlorobenzene, a member of triazoles, an organofluorine compound, a conazole fungicide and a triazole fungicide.
Production Methods
Fluquinconazole is commercially synthesised through a multi-step process that constructs its quinazolinone-triazole core. The synthesis begins with the preparation of 6-fluoroquinazolin-4-one, which serves as the central scaffold. This intermediate is then functionalized at the 2-position with a 1,2,4-triazol-1-yl group and at the 3-position with a 2,4-dichlorophenyl substituent. These substitutions are typically achieved through nucleophilic aromatic substitution and condensation reactions using appropriate halogenated precursors and triazole derivatives. The reactions are conducted under controlled temperature and solvent conditions to ensure high yield and purity.
Mechanism of action
Absorbed through foliage. Systemic with protectant and eradicant activity. Disrupts membrane function. Sterol biosynthesis inhibitor.
Metabolic pathway
The limited available published information states that fluconquinazole is metabolised to 1,2,4-triazole in plants and mammals. In soils it is hydrolysed slowly.
Degradation
Fluquinconazole is stable to light with a DT50 in water of 21.8 days (25 °C, PH 7> (PM).
Pesticide Type
Fungicide
FLUQUINCONAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
FLUQUINCONAZOLE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| The future of Shanghai Industrial Co., Ltd. | 021-61552785 | sales@shshiji.com | China | 9531 | 55 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
| Shanghai JONLN Reagent Co., Ltd. | 400-0066400 13621662912 | 422131432@qq.com | China | 9970 | 55 |
| Chengdu HuaXia Chemical Reagent Co. Ltd | 400-1166-196 13458535857 | cdhxsj@163.com | China | 13323 | 58 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4508 | 55 |
| Shanghai Boyners Pharm-Tech Co., Ltd. | 13817873692 | mkt@boynerspharm.com | China | 1707 | 55 |
