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1-acetyl-3,2-toluyl-5-fluorouracil

CAS No.
71861-76-2
Chemical Name:
1-acetyl-3,2-toluyl-5-fluorouracil
Synonyms
1-Acetyl-3-o-toluyl-5-fluorouracil;A-?OT-?Fu;1-acetyl-3,2-toluyl-5-fluorouracil;1 Acetyl 3 o toluyl 5 fluorouracil,1Acetyl3otoluyl5fluorouracil;2,4(1H,3H)-Pyrimidinedione, 1-acetyl-5-fluoro-3-(2-methylbenzoyl)-
CBNumber:
CB51367983
Molecular Formula:
C14H11FN2O4
Molecular Weight:
290.25
MDL Number:
MFCD01689616
MOL File:
71861-76-2.mol
MSDS File:
SDS
Last updated:2026-05-11 19:39:08

1-acetyl-3,2-toluyl-5-fluorouracil Properties

Melting point 141-143 °C(Solv: ethyl ether (60-29-7))
Boiling point 408.8±55.0 °C(Predicted)
Density 1.44±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka -5.29±0.40(Predicted)

1-acetyl-3,2-toluyl-5-fluorouracil price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Ambeed A1177646 1-Acetyl-3-o-toluyl-5-fluorouracil 99+% 71861-76-2 5mg $545 2026-06-05 Buy
American Custom Chemicals Corporation API0016876 ATOFLUDING 95.00% 71861-76-2 5MG $504.35 2021-12-16 Buy
Product number Packaging Price Buy
A1177646 5mg $545 Buy
API0016876 5MG $504.35 Buy

1-acetyl-3,2-toluyl-5-fluorouracil Chemical Properties, Uses, Production

Uses

1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antitumor agent and a 5-fluorouracil analog.

in vivo

Oral administration of 1-Acetyl-3-o-toluyl-5-fluorouracil demonstrates a remarkable effect on MH134 solid tumors, the effect being more marked than that of subcutaneous administration of 1-Acetyl-3-o-toluyl-5-fluorouracil. Anti-tumor activity of oral administration of 1-Acetyl-3-o-toluyl-5-fluorouracil at a dose of 0.2 mmol/kg/d is comparable to that of subcutaneous administration of 5-fluorouracil at the same dose. The level of decrease in thymus weight and the magnitude of increase of spleen weight following oral administration of 1-Acetyl-3-o-toluyl-5-fluorouracil at any dose are smaller than those by subcutaneous administration of 5-fluorouracil (0.2 mmol/kg/d)[1].

References

[1] Yata N, et al. Anti-tumor activity of 1-acetyl-3-o-toluyl-5-fluorouracil against murine hepatoma MH134 and its effects on tissue weights following subcutaneous and oral administration. J Pharmacobiodyn. 1985 Apr;8(4):264-9. DOI:10.1248/bpb1978.8.264

1-acetyl-3,2-toluyl-5-fluorouracil Preparation Products And Raw materials

Raw materials

Preparation Products

1-acetyl-3,2-toluyl-5-fluorouracil Suppliers

Global Suppliers ( 7)
Supplier Tel Email Country ProdList Advantage
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Shanghai Han-Xiang Chemical Co., Ltd. 17754423994 candy@biochempartner.com China 3057 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58

View Latest Price from 1-acetyl-3,2-toluyl-5-fluorouracil manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Acetyl-3-o-toluyl-5-fluorouracil pictures 2026-05-11 1-Acetyl-3-o-toluyl-5-fluorouracil
71861-76-2
$1520.00-2500.00 10g TargetMol Chemicals Inc.
1-Acetyl-3-o-toluyl-5-fluorouracil pictures 2025-07-26 1-Acetyl-3-o-toluyl-5-fluorouracil
71861-76-2
$1520.00-2500.00 10g TargetMol Chemicals Inc.

71861-76-2 (1-acetyl-3,2-toluyl-5-fluorouracil) Related Search:

1-acetyl-3,2-toluyl-5-fluorouracil A-?OT-?Fu 2,4(1H,3H)-Pyrimidinedione, 1-acetyl-5-fluoro-3-(2-methylbenzoyl)- 1 Acetyl 3 o toluyl 5 fluorouracil,1Acetyl3otoluyl5fluorouracil 1-Acetyl-3-o-toluyl-5-fluorouracil 71861-76-2