3-Bromocyclohexene
- CAS No.
- 1521-51-3
- Chemical Name:
- 3-Bromocyclohexene
- Synonyms
- 3-broMocyclohex-1-ene;3-Bromo-1-cyclohexene;3-BromocycL;3-Bromocyclohexene;TIMTEC-BB SBB007864;3-bromocyclohexylene;1-Bromo-2-cyclohexene;Cyclohexene, 3-bromo-;2-Cyclohexenyl bromide;3-Bromocyclohexene,95%
- CBNumber:
- CB5144817
- Molecular Formula:
- C6H9Br
- Molecular Weight:
- 161.04
- MDL Number:
- MFCD00013775
- MOL File:
- 1521-51-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 131-134 °C |
|---|---|
| Boiling point | 57-58 °C/12 mmHg (lit.) |
| Density | 1.4 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 130 °F |
| storage temp. | -20°C |
| form | Solid |
| color | White to off-white |
| Water Solubility | Not miscible or difficult to mix in water. |
| BRN | 635953 |
| InChI | InChI=1S/C6H9Br/c7-6-4-2-1-3-5-6/h2,4,6H,1,3,5H2 |
| InChIKey | AJKDUJRRWLQXHM-UHFFFAOYSA-N |
| SMILES | C1CCCC(Br)C=1 |
| CAS DataBase Reference | 1521-51-3(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H315-H319-H335 | |||||||||
| Precautionary statements | P210-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 10-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29038900 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
3-Bromocyclohexene price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 333549 | 3-Bromocyclohexene technical grade, 90% | 1521-51-3 | 10ml | $111 | 2026-04-30 | Buy |
| Sigma-Aldrich | 333549 | 3-Bromocyclohexene technical grade, 90% | 1521-51-3 | 50ml | $346 | 2026-04-30 | Buy |
| TCI Chemical | B0943 | 3-Bromocyclohexene >90.0%(GC) | 1521-51-3 | 5mL | $119 | 2026-04-30 | Buy |
| TCI Chemical | B0943 | 3-Bromocyclohexene >90.0%(GC) | 1521-51-3 | 25mL | $592 | 2026-04-30 | Buy |
| Matrix Scientific | 090492 | 3-Bromocyclohex-1-ene | 1521-51-3 | 5.00g | $42 | 2026-05-18 | Buy |
3-Bromocyclohexene Chemical Properties, Uses, Production
Chemical Properties
clear colorless to yellow liquid
Uses
3-Bromocyclohexene was used in the synthesis of N-tert-butoxycarbonyl-O-cyclohexyl-L-tyrosine. It was also used in the synthesis of enantiopure cyclohexitols such as muco-quercitol, D-chiro-inocitol and allo-inocitol.
Synthesis Reference(s)
Tetrahedron Letters, 26, p. 3863, 1985 DOI: 10.1016/S0040-4039(00)89271-0
Synthesis
110-83-8
1521-51-3
The general procedure for the synthesis of 3-bromocyclohexene from cyclohexene was as follows: cyclohexene (8.2 g, 0.1 mol) and N-bromosuccinimide (NBS, 21.4 g, 0.12 mol) were dissolved in carbon tetrachloride (CCl4, 100 mL) at room temperature, and azobisisobutyronitrile (AIBN, 3.3 g, 20 mmol) was subsequently added as initiator. . The reaction mixture was heated to reflux for 3 hours. Upon completion of the reaction, the reaction mixture was washed sequentially with sodium sulfite (Na2SO3) solution, saturated sodium bicarbonate (NaHCO3) solution and brine to remove unreacted reagents and by-products. The organic layer was dried with anhydrous sodium sulfate (Na2SO4) and subsequently concentrated under reduced pressure to afford the crude product 3-bromocyclohexene (8.5 g, 53% yield). The product did not require further purification and could be used directly in the subsequent reaction.
References
[1] Organic and Biomolecular Chemistry, 2008, vol. 6, # 20, p. 3751 - 3761
[2] Tetrahedron Letters, 2003, vol. 44, # 9, p. 1815 - 1817
[3] Journal of Organic Chemistry, 2014, vol. 79, # 18, p. 8786 - 8799
[4] Journal of the American Chemical Society, 2016, vol. 138, # 42, p. 13830 - 13833
[5] Journal of Chemical Research, Miniprint, 1981, # 2, p. 569 - 582
3-Bromocyclohexene Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ucheml Medicine Co., Ltd. | 0519-86058959 13775231161 | sales@uchemi.cn | China | 301 | 50 |
| Shanghai Pleikon Chemical Technology Co., Ltd | 021-54321516 17717324060 | 2719672468@qq.com | China | 2227 | 58 |
| Anyang Hongmeng New Materials Co., Ltd. | 19588588067 | 19588588067@163.com | China | 9979 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
View Latest Price from 3-Bromocyclohexene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 3-BROMOCYCLOHEXENE
1521-51-3
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2021-07-13 | 3-BROMOCYCLOHEXENE
1521-51-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 3-BROMOCYCLOHEXENE
1521-51-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 3-BROMOCYCLOHEXENE
1521-51-3
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3-BROMOCYCLOHEXENE
1521-51-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-BROMOCYCLOHEXENE
1521-51-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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