JKC-301
- CAS No.
- 136553-96-3
- Chemical Name:
- JKC-301
- Synonyms
- JKC-301;CYCLO(-D-ASP-PRO-D-ILE-LEU-D-TRP);JKC-301 Cyclo(-D-Asp-Pro-D-Ile-Leu-D-Trp);Cyclo(D-α-aspartyl-L-prolyl-D-isoleucyl-L-leucyl-D-tryptophyl);JKC 301 (CYCLO-[D-ASP-PRO-D-LLE-LEU-D-TR P]), SYNTHETIC, >99% PURITY
- CBNumber:
- CB5152346
- Molecular Formula:
- C32H44N6O7
- Molecular Weight:
- 624.73
- MDL Number:
- MFCD00214626
- MOL File:
- 136553-96-3.mol
- TDS File:
- TDS
JKC-301 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FJ108844 | JKC-301 Cyclo(-D-Asp-Pro-D-Ile-Leu-D-Trp) | 136553-96-3 | 500ug | $900 | 2026-06-04 | Buy |
| Biosynth | FJ108844 | JKC-301 Cyclo(-D-Asp-Pro-D-Ile-Leu-D-Trp) | 136553-96-3 | 1000ug | $900 | 2026-06-04 | Buy |
| Biosynth | FJ108844 | JKC-301 Cyclo(-D-Asp-Pro-D-Ile-Leu-D-Trp) | 136553-96-3 | 250ug | $900 | 2026-06-04 | Buy |
| Biosynth | FJ108844 | JKC-301 Cyclo(-D-Asp-Pro-D-Ile-Leu-D-Trp) | 136553-96-3 | 2000ug | $1100 | 2026-06-04 | Buy |
| Biosynth | FJ108844 | JKC-301 Cyclo(-D-Asp-Pro-D-Ile-Leu-D-Trp) | 136553-96-3 | 5000ug | $2400 | 2026-06-04 | Buy |
JKC-301 Chemical Properties,Uses,Production
Uses
JKC 301 is a selective Endothelin A receptor antagonist. JKC 301 attenuates the pressor effects of nicotine in rats. JKC 301 can be used to study cardiovascular disease caused by smoking[1][2].
References
[1] Tanus-Santos JE, Sampaio RC, Hyslop S, Franchini KG, Moreno H Jr. Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. Eur J Pharmacol. 2000 May 12;396(1):33-7. DOI:10.1016/s0014-2999(00)00194-1
[2] Ngoka LC, et al. Location of alkali metal binding sites in endothelin A selective receptor antagonists, cyclo(D-Trp-D-Asp-Pro-D-Val-Leu) and cyclo(D-Trp-D-Asp-Pro-D-Ile-Leu), from multistep collisionally activated decompositions. J Mass Spectrom. 2000 Feb;35(2):265-76. DOI:10.1002/(SICI)1096-9888(200002)35:2<265::AID-JMS946>3.0.CO;2-#
JKC-301 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 1010 | 55 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Alabiotech Inc. | 001-619-354-5251 | sales@alabiotech-e.com | United States | 972 | 60 |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 | Caroline@youngshechem.com | China | 4725 | 58 |
| Adachibio Inc. | +81-8027837258; | sales@adachibio.com | Japan | 938 | 58 |
