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Boc-3-(2-Naphthyl)-D-alanine

Boc-3-(2-Naphthyl)-D-alanine structure

CAS No.: 76985-10-9

Chemical Name:: Boc-3-(2-Naphthyl)-D-alanine

Synonyms: BOC-2-NAL-OH;BOC-NAL(2)-OH;BOC-D-2-NAL-OH;BOC-L-2-NAL-OH;Boc-2-D-Nal-OH;BOC-D-NAL(2)-OH;BOC-ALA(2-NAPH)-OH;RARECHEM BK PT 0098;RARECHEM BK PT 0101;BOC-D-ALA(2-NAPH)-OH

CBNumber:: CB5160608

Molecular Formula:: C18H21NO4

Molecular Weight:: 315.37

MDL Number:: MFCD00076900

MOL File:: 76985-10-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-21 10:31:43

Product description	Number	Pack Size	Price
Boc-D-2-Nal-OH ≥97.0% (HPLC)	15478	1g	$105
N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine >98.0%(HPLC)(T)	B3616	1g	$55
N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine >98.0%(HPLC)(T)	B3616	5g	$213
Boc-3-(2-Naphthyl)-D-alanine	B667360	50g	$555
Boc-3-(2-naphthyl)-D-alanine	FB47421	50g	$600
More product size

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Boc-3-(2-Naphthyl)-D-alanine Properties

Melting point	92-95 °C(lit.)
alpha	-45 º (c=1% in ethanol)
Boiling point	454.92°C (rough estimate)
Density	1.2164 (rough estimate)
refractive index	1.5740 (estimate)
storage temp.	Sealed in dry,2-8°C
solubility	Chloroform (Sparingly), Ethanol (Sparingly), Methanol (Slightly)
pka	3.88±0.30(Predicted)
form	Solid
color	White
optical activity	[α]20/D 45±2°, c = 1% in ethanol
BRN	4200660
Major Application	peptide synthesis
InChI	1S/C18H21NO4/c1-18(2,3)23-17(22)19-15(16(20)21)11-12-8-9-13-6-4-5-7-14(13)10-12/h4-10,15H,11H2,1-3H3,(H,19,22)(H,20,21)/t15-/m1/s1
InChIKey	URKWHOVNPHQQTM-OAHLLOKOSA-N
SMILES	CC(C)(C)OC(=O)N[C@H](Cc1ccc2ccccc2c1)C(O)=O
CAS DataBase Reference	76985-10-9(CAS DataBase Reference)
UNSPSC Code	12352200
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Safety Statements

22-24/25

WGK Germany

HazardClass

IRRITANT

HS Code

29242990

Storage Class

11 - Combustible Solids

NFPA 704

	1
0		0

Boc-3-(2-Naphthyl)-D-alanine price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	15478	Boc-D-2-Nal-OH ≥97.0% (HPLC)	76985-10-9	1g	$105	2023-01-07	Buy
TCI Chemical	B3616	N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine >98.0%(HPLC)(T)	76985-10-9	1g	$55	2026-03-19	Buy
TCI Chemical	B3616	N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine >98.0%(HPLC)(T)	76985-10-9	5g	$213	2026-03-19	Buy
TRC	B667360	Boc-3-(2-Naphthyl)-D-alanine	76985-10-9	50g	$555	2021-12-16	Buy
Biosynth Carbosynth	FB47421	Boc-3-(2-naphthyl)-D-alanine	76985-10-9	50g	$600	2021-12-16	Buy

Product number	Packaging	Price	Buy
15478	1g	$105	Buy
B3616	1g	$55	Buy
B3616	5g	$213	Buy
B667360	50g	$555	Buy
FB47421	50g	$600	Buy

Boc-3-(2-Naphthyl)-D-alanine Chemical Properties,Uses,Production

Chemical Properties

off-white granular powder

Uses

Boc-3-(2-Naphthyl)-D-alanine is a reagent in Lanreotide trisulfide synthesis and somatostatin receptor binding activity. Reagent in the preparation by coupling and structure-activity relationships of arginine containing tripeptides as MC4 receptor ligands.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

6960-34-5

(E)-N-((tert-Butoxycarbonyl)oxy)benziMidoyl cyanide

74651-77-7

56583-58-5

1. N-tert-butoxycarbonyl-L-3-(2-naphthyl)alanine (0.43 g, 2.0 mmol) was dissolved in a solvent mixture of dioxane (8 ml), water (8 ml) and triethylamine (4 ml). 2. BOC-ON (0.49 g, 2.0 mmol) was added and the reaction mixture was stirred overnight at room temperature under argon protection. 3. After completion of the reaction, water (30 ml) was added for dilution and extracted with ethyl acetate (3 x 20 ml). 4. The aqueous layer was adjusted to pH=4 with 10% citric acid solution and extracted again with ethyl acetate (3 x 20 ml). 5. The organic phases were combined, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give a colorless oily product (0.52 g, 82% yield). 6. The product was analyzed by 1H NMR. 6. The product was characterized by 1H NMR (DMSO-d6): δ 7.8 (3H, m), 7.7 (1H, s), 7.4 (3H, m), 7.15 (1H, d), 4.2 (1H, m), 3.2 (1H, m), 2.9 (1H, m), 1.3 (9H, s).

References

[1] Patent: US5486597, 1996, A

Boc-3-(2-Naphthyl)-D-alanine Preparation Products And Raw materials

Raw materials

3-(2-NAPHTHYL)-L-ALANINE (E)-N-((tert-Butoxycarbonyl)oxy)benziMidoyl cyanide Triethylamine Water 1,4-Dioxane

Preparation Products

Antide

Boc-3-(2-Naphthyl)-D-alanine Suppliers

Global( 269)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	+8618382028708	ni@enlaibio.com	China	1098	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29820	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	18895	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58

Supplier	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
GenicBio Limited	58
career henan chemical co	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
GL Biochem (Shanghai) Ltd.	58
Dideu Industries Group Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from Boc-3-(2-Naphthyl)-D-alanine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-29	Boc-d-2-nal-oh 76985-10-9	US $0.00-0.00 / kg	1kg	98%	1T	Sichuan HongRi Pharma-Tech Co.,Ltd
2026-04-20	Boc-D-2-Nal-OH 76985-10-9	US $55.00-39.00 / mg			10g	TargetMol Chemicals Inc.
2019-07-06	Boc-3-(2-Naphthyl)-D-alanine 76985-10-9	US $1.00 / KG	1KG	99%	20kg	Career Henan Chemical Co

Boc-d-2-nal-oh
76985-10-9
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

Boc-D-2-Nal-OH
76985-10-9
US $55.00-39.00 / mg
TargetMol Chemicals Inc.

Boc-3-(2-Naphthyl)-D-alanine
76985-10-9
US $1.00 / KG
99%
Career Henan Chemical Co

Boc-3-(2-Naphthyl)-D-alanine Spectrum

Boc-3-(2-Naphthyl)-D-alanine(76985-10-9)FT-IR

76985-10-9(Boc-3-(2-Naphthyl)-D-alanine)Related Search:

D-Alanine Boc-3-(2-Naphthyl)-L-alanine EC 2.6.1.2 Phenprobamate DL-Alanine

Boc-beta-alanine β-Alanine 1-(1-NAPHTHYL)-2-THIOUREA L-Alanine DI-TERT-BUTYL ETHER

BOC-L-4-Chlorophe BOC-L-2-Methylphe 5-Chloro-2-iodobenzoic acid BOC-L-3-THIENYLALANINE DCHA SALT BOC-D-4-Nitrophe

Boc-L-serine methyl ester BOC-D-2-CYANOPHENYLALANINE BOC-D-SER-OME

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Boc-D-2-Nal-OH Boc-3-(2-Naphthyl)-D-Alanine N-Boc-3-(2-naphthyl)-D-alanine (R)-alpha-tert-Butoxycarbonylamino-2-naphthalenepropionic Acid (R)-alpha-(Boc-amino)-2-naphthalenepropionic Acid 2-Naphthalenepropanoicacid, a-[[(1,1-diMethylethoxy)carbonyl]aMino]-,(aR)- N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine N-Boc-2-(2-naphthyl)-D-alanine BOC-NAL(2)-OH BOC-ALA(2-NAPH)-OH BOC-ALA(2-NAPHTHYL)-OH BOC-ALA-BETA-(2-NAPHTHYL)-OH BOC-BETA-(2-NAPHTHYL)-D-ALANINE BOC-BETA-(2-NAPHTHYL)-L-ALANINE BOC-D-3-(2-NAPHTHYL)-ALANINE BOC-D-2-NAL-OH BOC-D-2-NAPHTHYLALANINE BOC-D-ALA(2-NAPH)-OH BOC-D-ALA(2-NAPHTHYL)-OH BOC-D-ALA-BETA-(2-NAPHTHYL)-OH BOC-L-2-NAL-OH BOC-L-2-NAPHTHYLALANINE BOC-L-3-(2-NAPHTHYL)-ALANINE BOC-D-NAL(2)-OH BOC-2-L-NAPHTHYLALANINE BOC-2-NAL-OH BOC-3-(2-NAPHTHYL)-ALANINE BOC-3-(2-NAPHTHYL)-D-ALANINE (R)-N-BOC-2-NAPHTHYLALANINE (R)-N-BOC-2-NAPHTHYLALANINE, 95%, 98% EE (Tert-Butoxy)Carbonyl D-2-Nal-OH (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-naphthalen-2-ylpropanoic acid Boc-3-(2-naphthyl)-D-alanine≥ 99% (HPLC) (2R)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-(2-naphthalenyl)propanoate N-Boc-3-(2-naphthyl)-D-alanine BOC-(2-naphthyl)-D-alanine (S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(NAPHTHALEN-2-YL)PROPANOIC ACID (S)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID (S)-N-BOC-2-NAPHTHYLALANINE (R)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(NAPHTHALEN-2-YL)PROPANOIC ACID (R)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID RARECHEM BK PT 0098 RARECHEM BK PT 0101 N-TERT-BUTOXYCARBONYL-2-NAPHTHYL-D-ALANINE N-TERT-BUTOXYCARBONYL-2-NAPHTHYL-L-ALANINE N-T-BOC-D-3-(2-NAPHTHYL)-ALANINE N-ALPHA-TERT-BUTYLOXYCARBONYL-3-(2-NAPHTHYL)-D-ALANINE N-ALPHA-(TERT-BUTYLOXYCARBONYL)-3-(2-NAPHTHYL)-L-ALANINE N-ALPHA-(T-BUTYLOXYCARBONYL)-3-(2-NAPHTHYL)-D-ALANINE N-ALPHA-T-BUTOXYCARBONYL-L-3-(2-NAPHTHYL)-ALANINE N-ALPHA-T-BUTOXYCARBONYL-3-(2-NAPHTHYL)-D-ALANINE N-ALPHA-T-BUTOXYCARBONYL-3-(2-NAPHTHYL)-L-ALANINE N-ALPHA-T-BOC-BETA-(2-NAPHTHYL)-D-ALANINE N-ALPHA-T-BOC-BETA-(2-NAPHTHYL)-L-ALANINE N-BOC-3-(2-NAPHTHYL)-L-ALANINE (R)-N-BOC-2-Naphthylalanine, 98% ee, 95% Boc-2-D-Nal-OH 3-Naphth-2-yl-D-alanine, N-BOC protected N-(tert-Butoxycarbonyl)-3-(2-naphthyl)-D-alanine > 2-Naphthalenepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αR)- (R)-alpha-(Boc-amino)-2-naphthalenepropionic Acid