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N-BUTYL-2-CHLORO-ACETAMIDE

N-BUTYL-2-CHLORO-ACETAMIDE Structure
N-BUTYL-2-CHLORO-ACETAMIDE structure
CAS No.
5349-24-6
Chemical Name:
N-BUTYL-2-CHLORO-ACETAMIDE
Synonyms
TIMTEC-BB SBB010319;N-BUTYL-2-CHLORACETAMIDE;ASINEX-REAG BAS 02927056;N-BUTYL-2-CHLORO-ACETAMIDE;N-butyl-2-chloro-ethanamide;Acetamide, N-butyl-2-chloro-
CBNumber:
CB5177802
Molecular Formula:
C6H12ClNO
Molecular Weight:
149.62
MDL Number:
MFCD00776256
MOL File:
5349-24-6.mol
Last updated:2025-07-24 18:13:49
Product description Number Pack Size Price
N-Butyl-2-chloro-acetamide 018561 500.00mg $182
N-Butyl-2-chloroacetamide 97% B41547 250mg $65
N-Butyl-2-chloroacetamide 97% B41547 1g $90
N-Butyl-2-chloroacetamide 97% B41547 10g $220
N-Butyl-2-chloroacetamide 97% B41547 5g $450
More product size
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N-BUTYL-2-CHLORO-ACETAMIDE Properties

Melting point 96.5 °C(Solv: benzene (71-43-2))
Boiling point 110 °C(Press: 7.0 Torr)
Density 1.032±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 14.38±0.46(Predicted)
Appearance Colorless to light yellow Liquid
FDA UNII 2UR7NWC4RK

SAFETY

Risk and Safety Statements

Hazard Codes  Xi,Xn
Risk Statements  22
HazardClass  IRRITANT
HS Code  2924297099

N-BUTYL-2-CHLORO-ACETAMIDE price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 018561 N-Butyl-2-chloro-acetamide 5349-24-6 500.00mg $182 2026-05-18 Buy
Synthonix B41547 N-Butyl-2-chloroacetamide 97% 5349-24-6 250mg $65 2026-05-06 Buy
Synthonix B41547 N-Butyl-2-chloroacetamide 97% 5349-24-6 1g $90 2026-05-06 Buy
Synthonix B41547 N-Butyl-2-chloroacetamide 97% 5349-24-6 10g $220 2026-05-06 Buy
Synthonix B41547 N-Butyl-2-chloroacetamide 97% 5349-24-6 5g $450 2026-05-06 Buy
Product number Packaging Price Buy
018561 500.00mg $182 Buy
B41547 250mg $65 Buy
B41547 1g $90 Buy
B41547 10g $220 Buy
B41547 5g $450 Buy

N-BUTYL-2-CHLORO-ACETAMIDE Chemical Properties,Uses,Production

Synthesis

Butylamine

109-73-9

Chloroacetyl chloride

79-04-9

N-BUTYL-2-CHLORO-ACETAMIDE

5349-24-6

GENERAL STEPS: Chloroacetyl chloride (0.2 mol, 15.9 mL, CAS: 79-04-9) was slowly added dropwise to a solution of dichloromethane (50 mL) containing n-butylamine (0.2 mol, 14.83 g) in an ice bath. After the dropwise addition, 20% NaOH aqueous solution was added and the reaction mixture was warmed up to room temperature and stirring was continued for 2 hours. After completion of the reaction, the organic phase was separated and washed sequentially with 5% aqueous HCl and 5% aqueous NaHCO3 (3 x 25 mL each). The organic phase was dried and filtered, and then the solvent was removed by distillation under reduced pressure to give the intermediate N-butyl-2-chloroacetamide (92% yield). Subsequently, the intermediate (0.05 mol, 9.00 g) was mixed with 5,6,7,8-tetrahydropyrido[1,2-α]imidazole (0.05 mol, 6.11 g, CAS: 34167-66-3) in acetonitrile (50 mL) and the reaction was carried out at reflux for 18 hours. The reaction solution was recrystallized by ethyl acetate recrystallization operation to give the product [4C-imCH2CONHBu]Cl (89% yield). Finally, [4C-imCH2CONHBu]OH was obtained by treatment with anion exchange resin.

References

[1] Patent: CN104326949, 2016, B. Location in patent: Paragraph 0060; 0061; 0063
[2] Patent: WO2007/9083, 2007, A2. Location in patent: Page/Page column 68
[3] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 6, p. 678 - 681
[4] ChemMedChem, 2018,
[5] Organic Letters, 2004, vol. 6, # 26, p. 4805 - 4808

N-BUTYL-2-CHLORO-ACETAMIDE Preparation Products And Raw materials

Raw materials

Ethyl 4-chloroacetoacetate Butylamine Chloroacetyl chloride Water Dichloromethane
Sodium hydroxide

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Preparation Products

N-BUTYL-2-CHLORO-ACETAMIDE Suppliers

Global( 72)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63645 58
career henan chemical co 		+86-0371-86658258 factory@coreychem.com China 29780 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-87569266 +86-17392581500 1015@dideu.com China 3861 58
Aladdin Scientific 		tp@aladdinsci.com United States 54746 58
Qingdao Dexin Chemical Co., Ltd 		+86-15553333686 15553333686@qq.com China 3113 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Supplier Advantage
Alchem Pharmtech,Inc. 		58
career henan chemical co 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Aladdin Scientific 		58
Qingdao Dexin Chemical Co., Ltd 		58
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Hanhong Scientific Co.,Ltd. 64
Shanghai Topbiochem Technology Co., Ltd 58

View Lastest Price from N-BUTYL-2-CHLORO-ACETAMIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-BUTYL-2-CHLORO-ACETAMIDE pictures 2020-01-10 N-BUTYL-2-CHLORO-ACETAMIDE
5349-24-6
 $1.00 1g 99.0% 100kg Career Henan Chemical Co

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ASINEX-REAG BAS 02927056 N-BUTYL-2-CHLORO-ACETAMIDE TIMTEC-BB SBB010319 N-BUTYL-2-CHLORACETAMIDE N-butyl-2-chloro-ethanamide Acetamide, N-butyl-2-chloro- 5349-24-6