1-Amino-3,6,9-trioxaundecanyl-11-ol
- CAS No.
- 86770-74-3
- Chemical Name:
- 1-Amino-3,6,9-trioxaundecanyl-11-ol
- Synonyms
- NH2-PEG4-OH;NH2-PEG4;2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethanol;H2N-PEG4-OH;Amino-PEG4-alcohol;Amino-dPEG(R)4-OH;Tetraethylene Glycol MonoaMine;t4egma;H2N-dPEG4)-OH;Amino-PEG3-ol
- CBNumber:
- CB1472260
- Molecular Formula:
- C8H19NO4
- Molecular Weight:
- 193.24
- MDL Number:
- MFCD01752874
- MOL File:
- 86770-74-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 301.6±27.0 °C(Predicted) |
|---|---|
| Density | 1.068±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 14.36±0.10(Predicted) |
| form | solid or viscous liquid |
| color | Colourless to Dark Brown |
| Appearance | colorless to yellowish oil |
| Water Solubility | Water: 50 mg/mL (258.75 mM) |
| InChI | InChI=1S/C8H19NO4/c9-1-3-11-5-7-13-8-6-12-4-2-10/h10H,1-9H2 |
| InChIKey | ANOJXMUSDYSKET-UHFFFAOYSA-N |
| SMILES | C(O)COCCOCCOCCN |
| CAS DataBase Reference | 86770-74-3 |
| EPA Substance Registry System | Ethanol, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]- (86770-74-3) |
| UNSPSC Code | 51171641 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | WGK 3 |
| TSCA | TSCA listed |
| HS Code | 2922190090 |
| Storage Class | 11 - Combustible Solids |
1-Amino-3,6,9-trioxaundecanyl-11-ol price More Price(104)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | QBD10249 | Amino-dPEG®4-OH | 86770-74-3 | 100MG | $157 | 2026-04-30 | Buy |
| Sigma-Aldrich | QBD10249 | Amino-dPEG®4-OH | 86770-74-3 | 1000MG | $315 | 2026-04-30 | Buy |
| Sigma-Aldrich | CDS020855 | 2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethanol | 86770-74-3 | 50 mg | $45.5 | 2026-04-30 | Buy |
| Usbiological | A1381-58 | 1-Amino-3,6,9-trioxaundecanyl-11-ol | 100mg | $333 | 2026-06-03 | Buy | |
| Usbiological | 516839 | Amino-PEG4-Alcohol (Tetraethylene glycol monoamine) ≥95% | 86770-74-3 | 25g | $1168 | 2026-06-03 | Buy |
1-Amino-3,6,9-trioxaundecanyl-11-ol Chemical Properties,Uses,Production
Description
Amino-PEG4-alcohol is a very popular PEG reagent containing an amino group (NH2) with a hydroxyl group (OH). The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Chemical Properties
Pale Yellow Oil
Uses
1-Amino-3,6,9-trioxaundecanyl-11-ol can be used in a test kit to detect progesterone.
reaction suitability
reagent type: cross-linking reagent
reactivity: carboxyl reactive
Synthesis
86770-67-4
86770-74-3
General procedure for the synthesis of 1-amino-3,6,9-trioxa-11-undecanol from 11-azido-3,6,9-trioxa-11-undecanol: the azide was mixed with Pd/C catalyst (150 mg) in methanol (7.0 mL) and the reaction was stirred for 12 h under hydrogen atmosphere (1 atm). Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration and the filtrate was concentrated to afford the target product 1-amino-3,6,9-trioxa-11-undecanol in quantitative yield (0.520 g, 2.7 mmol). Ref: Xie, H. Z.; Braha, O.; Gu, L. Q.; Cheley, S.; Bayley, H. Chem. Biol. 2005, 12, 109-120.
IC 50
PEGs; Non-cleavable Linker
References
[1] Helvetica Chimica Acta, 1991, vol. 74, # 8, p. 1697 - 1706
[2] Organic Letters, 2009, vol. 11, # 1, p. 193 - 196
[3] Angewandte Chemie - International Edition, 2015, vol. 54, # 35, p. 10327 - 10330
[4] Angew. Chem., 2015, vol. 35, # 37, p. 10467 - 10471,5
[5] Chemistry - A European Journal, 2018, vol. 24, # 4, p. 813 - 817
1-Amino-3,6,9-trioxaundecanyl-11-ol Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
| Shanghai Huici Pharmaceutical Technology Co., LTD | 133-31922809 19372841038 | lixing@pharmahuici.com | China | 853 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 043180534350 19917294565 | et@chemextension.com | China | 4446 | 58 |
| Shanghai Yanfen Biochemical Technology Co.,LTD | 13611955358 15002190549 | yanfen2023@126.com | China | 2573 | 58 |
| Chemyouth Life Science(Suzhou)Co.,Ltd | 18605123100 | kaiyuezhang@chemyouth.com | China | 153 | 58 |
| Yangzhou Jide Kangrui Biotechnology Co., Ltd. | 15029750239 | 1002921772@qq.com | China | 1009 | 58 |
| Shandong Mingde Biotechnology Co., Ltd. | 18560864701 | 2037956468@qq.com | China | 831 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
View Lastest Price from 1-Amino-3,6,9-trioxaundecanyl-11-ol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-25 | Amino-PEG4-alcohol
86770-74-3
|
$2.00-6.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
![]() |
2026-07-24 | 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethanol
86770-74-3
|
1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. | ||
![]() |
2026-07-24 | NH2-PEG4-OH
86770-74-3
|
1g | 98% | 1g/bottle, 10g/bottle, 100g/bottle | XIAMEN SINOPEG BIOTECH CO., LTD. |
-

- Amino-PEG4-alcohol
86770-74-3
- $2.00-6.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethanol
86770-74-3
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
-

- NH2-PEG4-OH
86770-74-3
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
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